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Protein

TATA-box-binding protein

Gene

tbp

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-982-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding protein
Alternative name(s):
Box A-binding protein
Short name:
BAP
TATA sequence-binding protein
Short name:
TBP
TATA-box factor
Gene namesi
Name:tbp
Ordered Locus Names:PH1009
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001540201 – 191TATA-box-binding proteinAdd BLAST191

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1009

Structurei

3D structure databases

ProteinModelPortaliO58737
SMRiO58737
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati11 – 871Add BLAST77
Repeati102 – 1782Add BLAST77

Sequence similaritiesi

Belongs to the TBP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764 Archaea
COG2101 LUCA
HOGENOMiHOG000105163
KOiK03120
OMAiQAFEMIY
OrthoDBiPOG093Z0B8S

Family and domain databases

CDDicd04518 TBP_archaea, 1 hit
Gene3Di3.30.310.10, 2 hits
HAMAPiMF_00408 TATA_bind_prot_arch, 1 hit
InterProiView protein in InterPro
IPR000814 TBP
IPR033711 TBP_archaea
IPR030491 TBP_CS
IPR012295 TBP_dom_sf
PANTHERiPTHR10126 PTHR10126, 1 hit
PfamiView protein in Pfam
PF00352 TBP, 2 hits
PRINTSiPR00686 TIFACTORIID
PROSITEiView protein in PROSITE
PS00351 TFIID, 2 hits

Sequencei

Sequence statusi: Complete.

O58737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDTSNVKLR IENIVASVDL FAQLDLEKVL DICPNSKYNP EEFPGIICRF
60 70 80 90 100
DDPKVALLIF SSGKLVVTGA KSIQDIERAV AKLIQKLKGI GVKFKRAPLI
110 120 130 140 150
DVQNMVFSGD IGREFNLDNV ALTLPNCEYE PEQFPGVIYR VKEPRAVILL
160 170 180 190
FSSGKIVCSG AKSEADAWEA VRKLLRELEK YGLIEEEEEE L
Length:191
Mass (Da):21,373
Last modified:August 1, 1998 - v1
Checksum:i85E8AD2A0FADF589
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30106.1
PIRiD71093
RefSeqiWP_010885095.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA30106; BAA30106; BAA30106
GeneIDi1443330
KEGGipho:PH1009

Similar proteinsi

Entry informationi

Entry nameiTBP_PYRHO
AccessioniPrimary (citable) accession number: O58737
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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