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Protein
Submitted name:

180aa long hypothetical pyrazinamidase/nicotinamidase

Gene

PH0999

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei10Proton donor/acceptorCombined sources1
Metal bindingi52ZincCombined sources1
Metal bindingi54Zinc; via tele nitrogenCombined sources1
Metal bindingi71Zinc; via tele nitrogenCombined sources1
Sitei94Important for catalytic activityCombined sources1
Binding sitei129Substrate; via amide nitrogenCombined sources1
Active sitei133NucleophileCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-bindingCombined sources, ZincCombined sources

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-990-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
180aa long hypothetical pyrazinamidase/nicotinamidaseImported
Gene namesi
Ordered Locus Names:PH0999Imported
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)Imported
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi70601.PH0999.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ILWX-ray2.05A1-180[»]
1IM5X-ray1.65A1-180[»]
ProteinModelPortaliO58727.
SMRiO58727.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO58727.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 177IsochorismataseInterPro annotationAdd BLAST173

Phylogenomic databases

eggNOGiarCOG01943. Archaea.
COG1335. LUCA.
HOGENOMiHOG000078666.
KOiK08281.
OMAiICGTLAN.
OrthoDBiPOG093Z0BK6.

Family and domain databases

InterProiView protein in InterPro
IPR000868. Isochorismatase-like.
PfamiView protein in Pfam
PF00857. Isochorismatase. 1 hit.
SUPFAMiSSF52499. SSF52499. 1 hit.

Sequencei

Sequence statusi: Complete.

O58727-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEEALIVVD MQRDFMPGGA LPVPEGDKII PKVNEYIRKF KEKGALIVAT
60 70 80 90 100
RDWHPENHIS FRERGGPWPR HCVQNTPGAE FVVDLPEDAV IISKATEPDK
110 120 130 140 150
EAYSGFEGTD LAKILRGNGV KRVYICGVAT EYCVRATALD ALKHGFEVYL
160 170 180
LRDAVKGIKP EDEERALEEM KSRGIKIVQF
Length:180
Mass (Da):20,192
Last modified:August 1, 1998 - v1
Checksum:i7FFEE8E90C0EE89C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30096.1.
PIRiB71092.
RefSeqiWP_010885086.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA30096; BAA30096; BAA30096.
GeneIDi1443321.
KEGGipho:PH0999.

Similar proteinsi

Entry informationi

Entry nameiO58727_PYRHO
AccessioniPrimary (citable) accession number: O58727
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: August 30, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported