Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Divalent-cation tolerance protein CutA

Gene

cutA

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in resistance toward heavy metals.

Cofactori

Cu cationCuratedNote: Binds 1 copper ion in the interface between two trimers.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi48Copper1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCopper, Metal-binding

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-967-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Divalent-cation tolerance protein CutA
Gene namesi
Name:cutA
Ordered Locus Names:PH0992
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001571291 – 102Divalent-cation tolerance protein CutAAdd BLAST102

Interactioni

Subunit structurei

Homotrimer. The binding of the copper ion probably leads to oligomerization.

Protein-protein interaction databases

STRINGi70601.PH0992

Structurei

Secondary structure

1102
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 10Combined sources9
Helixi11 – 23Combined sources13
Beta strandi28 – 41Combined sources14
Beta strandi44 – 57Combined sources14
Helixi59 – 61Combined sources3
Helixi62 – 72Combined sources11
Beta strandi74 – 77Combined sources4
Beta strandi81 – 84Combined sources4
Beta strandi86 – 88Combined sources3
Helixi90 – 99Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1J2VX-ray2.00A1-102[»]
1UKUX-ray1.45A1-102[»]
1UMJX-ray1.60A/B1-102[»]
2E66X-ray2.00A/B/C1-102[»]
4NYOX-ray1.80A/B/C/D/E/F1-102[»]
4NYPX-ray2.00A/B/C/D/E/F1-102[»]
ProteinModelPortaliO58720
SMRiO58720
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO58720

Family & Domainsi

Sequence similaritiesi

Belongs to the CutA family.Curated

Phylogenomic databases

eggNOGiarCOG04231 Archaea
COG1324 LUCA
HOGENOMiHOG000222826
KOiK03926
OMAiSVYRWQG
OrthoDBiPOG093Z0L3R

Family and domain databases

Gene3Di3.30.70.120, 1 hit
InterProiView protein in InterPro
IPR004323 Ion_tolerance_CutA
IPR011322 N-reg_PII-like_a/b
IPR015867 N-reg_PII/ATP_PRibTrfase_C
PANTHERiPTHR23419 PTHR23419, 1 hit
PfamiView protein in Pfam
PF03091 CutA1, 1 hit
SUPFAMiSSF54913 SSF54913, 1 hit

Sequencei

Sequence statusi: Complete.

O58720-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIVYTTFPD WESAEKVVKT LLKERLIACA NLREHRAFYW WEGKIEEDKE
60 70 80 90 100
VGAILKTRED LWEELKERIK ELHPYDVPAI IRIDVDDVNE DYLKWLIEET

KK
Length:102
Mass (Da):12,348
Last modified:August 1, 1998 - v1
Checksum:iDC17341ECFDD8401
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30089.1
PIRiC71091
RefSeqiWP_010885081.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA30089; BAA30089; BAA30089
GeneIDi1443316
KEGGipho:PH0992

Similar proteinsi

Entry informationi

Entry nameiCUTA_PYRHO
AccessioniPrimary (citable) accession number: O58720
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health