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Protein

Iron-sulfur cluster carrier protein

Gene

PH0949

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi38 – 45ATPUniRule annotation8

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Iron, Iron-sulfur, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-945-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Iron-sulfur cluster carrier proteinUniRule annotation
Gene namesi
Ordered Locus Names:PH0949
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001849561 – 295Iron-sulfur cluster carrier proteinAdd BLAST295

Proteomic databases

PRIDEiO58667.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi70601.PH0949.

Structurei

3D structure databases

ProteinModelPortaliO58667.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Mrp/NBP35 ATP-binding proteins family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00585. Archaea.
COG0489. LUCA.
HOGENOMiHOG000079916.
KOiK03593.
OMAiATDCKLI.

Family and domain databases

CDDicd02037. MRP-like. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_02040. Mrp_NBP35. 1 hit.
InterProiIPR019591. Mrp/NBP35_ATP-bd.
IPR000808. Mrp_CS.
IPR027417. P-loop_NTPase.
IPR033756. YlxH/NBP35.
[Graphical view]
PANTHERiPTHR23264. PTHR23264. 1 hit.
PfamiPF10609. ParA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS01215. MRP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O58667-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIKTPTVKV PGLGTDPLEQ RIKEKEKKWK YKIAVLSGKG GVGKSTVAVN
60 70 80 90 100
LTAALAKMGY FVGILDADIH GPNVAKMLGV DKEEVYAEKF DDGHFEMIPP
110 120 130 140 150
TTDFMGQVTP IKVMSMGMMV PEDQPVIWRG PLVTKAIKQL LGDVKWGSLD
160 170 180 190 200
FMIIDFPPGT GDEILTVVQS IKLDAAIIVT TPQEVALLDT GKAVNMMKKM
210 220 230 240 250
EVPYVAVVEN MSYLICPHCG NKIDIFGEGG GEKLAQKEGV DFLGKIPIDL
260 270 280 290
KAREASDLGI PIVLYEDTPA AKAFMELAEK LVNKLKEIKG DGGKE
Length:295
Mass (Da):32,033
Last modified:August 1, 1998 - v1
Checksum:iECB9CC105ADE84A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30046.1.
PIRiH71085.
RefSeqiWP_010885042.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA30046; BAA30046; BAA30046.
GeneIDi1443277.
KEGGipho:PH0949.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30046.1.
PIRiH71085.
RefSeqiWP_010885042.1. NC_000961.1.

3D structure databases

ProteinModelPortaliO58667.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH0949.

Proteomic databases

PRIDEiO58667.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA30046; BAA30046; BAA30046.
GeneIDi1443277.
KEGGipho:PH0949.

Phylogenomic databases

eggNOGiarCOG00585. Archaea.
COG0489. LUCA.
HOGENOMiHOG000079916.
KOiK03593.
OMAiATDCKLI.

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-945-MONOMER.

Family and domain databases

CDDicd02037. MRP-like. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_02040. Mrp_NBP35. 1 hit.
InterProiIPR019591. Mrp/NBP35_ATP-bd.
IPR000808. Mrp_CS.
IPR027417. P-loop_NTPase.
IPR033756. YlxH/NBP35.
[Graphical view]
PANTHERiPTHR23264. PTHR23264. 1 hit.
PfamiPF10609. ParA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS01215. MRP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAPBC_PYRHO
AccessioniPrimary (citable) accession number: O58667
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.