Reviewed, UniProtKB/Swiss-Prot O58496 (IORB_PYRHO)

Names and origin

Protein names

Recommended name:
    Indolepyruvate oxidoreductase subunit iorB
      Short name=IOR
    EC=1.2.7.8
Alternative name(s):
    Indolepyruvate ferredoxin oxidoreductase subunit beta

Gene names

Name:	iorB
Ordered Locus Names:	PH0764

Organism

Pyrococcus horikoshii [Complete proteome] [HAMAP]

Taxonomic identifier

53953 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates By similarity.
Catalytic activity	(Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+.
Subunit structure	Heterodimer of the iorA and iorB subunits.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro indolepyruvate ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 202	202	Indolepyruvate oxidoreductase subunit iorB		PRO_0000099935

Sequences

	Sequence		Length	Mass (Da)
	O58496-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: E430872F6F4FF9EE	FASTA	202	21,810
	10 20 30 40 50 60 MKEYNIVITG VGGQGILTAA NLLGWAALKA GYKVRVGEVH GMSQRFGSVI AYVRFGDDVY 70 80 90 100 110 120 GAMVPEGKAD VILSFEPVEA LRYINYLKKG GLVFTNARPI PPVQVSMGLA TYPSLEEIKR 130 140 150 160 170 180 IVEEEFNGKF LAFDAEKLAI EAGNVITTNV VLIGALTQTP GFPLSAEHVK EVIRLSVPPK 190 200 AVDVNMKAFD LGVKAAKEML NL

References

[1]

"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3." Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H. DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OT3.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000001 Genomic DNA. Translation: BAA29855.1.
PIR	E71124.
RefSeq	NP_142701.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1443090.
GenomeReviews	Gene locus PH0764 in contig BA000001_GR.
KEGG	pho:PH0764.
NMPDR	fig|70601.1.peg.743.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O58496.
OMA	O58496. ALRYINY.
Enzyme and pathway databases
BRENDA	1.2.7.8. 74679.
Family and domain databases
InterPro	IPR017719. Indolepyruvate_Fd_OxRdtase_bsu. IPR019752. Pyrv/ketoisovalerate_OxRed. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
Pfam	PF01558. POR. 1 hit. [Graphical view]
TIGRFAMs	TIGR03334. IOR_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IORB_PYRHO

Accession

Primary (citable) accession number: O58496

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)