Reviewed, UniProtKB/Swiss-Prot O58417 (PORB_PYRHO)

Names and origin

Protein names

Recommended name:
    Pyruvate synthase subunit porB
    EC=1.2.7.1
Alternative name(s):
    Pyruvate oxidoreductase beta chain
      Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit beta

Gene names

Name:	porB
Ordered Locus Names:	PH0685

Organism

Pyrococcus horikoshii [Complete proteome] [HAMAP]

Taxonomic identifier

53953 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain By similarity.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	pyruvate synthase activity Inferred from electronic annotation. Source: EC thiamin pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 331	330	Pyruvate synthase subunit porB		PRO_0000099908

Sequences

	Sequence		Length	Mass (Da)
	O58417-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 2E5FDCE5B6791C25	FASTA	331	36,119
	10 20 30 40 50 60 MAVRKPPITT REYWAPGHAA CAGCGCAIAL KLATKAFSEA MEEKYGDPNA FAIAQATGCM 70 80 90 100 110 120 EVVSAVFPYT AWKVPWIHVA FENAAAAASG VEAAWKKLGI KGKILAIGGD GGTADIGLQA 130 140 150 160 170 180 LSGMLERGHN VVYLMYDNEA YMNTGIQRSS STPYGAWTTT SPPGKYSIGE DRPKKWVALI 190 200 210 220 230 240 AAAHQIPYAA TASIGNPFDL VKKVKKAAKV DGPAFIQVHC TCPTGWRTPL EKGVEIARLA 250 260 270 280 290 300 IETGMWPLFE IENGDIWNIK IQPPGGGAKV YKEGGRVVRI EFKKPIEEYL KYQGRFKHLF 310 320 330 KRPEAIEELR NQIKAMWKVL GVEAILPRPE E

References

[1]

"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3." Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H. DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OT3.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000001 Genomic DNA. Translation: BAA29776.1. Different initiation.
PIR	F71114.
RefSeq	NP_142634.1.
3D structure databases
HSSP	HSSP built from PDB template 1KEK based on UniProtKB P94692.
ModBase	Search...
Genome annotation databases
GeneID	1443012.
GenomeReviews	Gene locus PH0685 in contig BA000001_GR.
KEGG	pho:PH0685.
NMPDR	fig|70601.1.peg.665.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O58417.
OMA	YICLDNE.
Enzyme and pathway databases
BRENDA	1.2.7.1. 74679.
Family and domain databases
InterPro	IPR011766. TPP_enzyme_bd_C. [Graphical view]
Pfam	PF02775. TPP_enzyme_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PORB_PYRHO

Accession

Primary (citable) accession number: O58417

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 23, 2007
Last modified:	November 3, 2009
This is version 47 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)