ID   PORC_PYRHO              Reviewed;         185 AA.
AC   O58411;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   16-JUN-2009, entry version 48.
DE   RecName: Full=Pyruvate/ketoisovalerate oxidoreductases common subunit gamma;
DE   Includes:
DE     RecName: Full=Pyruvate synthase subunit porC;
DE              EC=1.2.7.1;
DE     AltName: Full=Pyruvate oxidoreductase gamma chain;
DE              Short=POR;
DE     AltName: Full=Pyruvic-ferredoxin oxidoreductase subunit gamma;
DE   Includes:
DE     RecName: Full=Ketoisovalerate oxidoreductase subunit vorC;
DE              Short=VOR;
DE              EC=1.2.7.7;
DE     AltName: Full=2-oxoisovalerate oxidoreductase gamma chain;
DE     AltName: Full=2-oxoisovalerate ferredoxin reductase subunit gamma;
GN   Name=porG; OrderedLocusNames=PH0678;
OS   Pyrococcus horikoshii.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=53953;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OT3;
RX   MEDLINE=98344137; PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y.,
RA   Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y.,
RA   Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K.,
RA   Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin =
CC       acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+).
CC   -!- CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + CoA + 2 oxidized
CC       ferredoxin = S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced
CC       ferredoxin + H(+).
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one
CC       gamma chain.
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DR   EMBL; BA000001; BAA29769.1; -; Genomic_DNA.
DR   PIR; G71113; G71113.
DR   RefSeq; NP_142628.1; -.
DR   GeneID; 1443006; -.
DR   GenomeReviews; BA000001_GR; PH0678.
DR   KEGG; pho:PH0678; -.
DR   NMPDR; fig|70601.1.peg.659; -.
DR   HOGENOM; O58411; -.
DR   OMA; O58411; KEIRIHG.
DR   BRENDA; 1.2.7.1; 74679.
DR   BRENDA; 1.2.7.7; 74679.
DR   GO; GO:0043807; F:3-methyl-2-oxobutanoate dehydrogenase (ferr...; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0019164; F:pyruvate synthase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR011894; PorC_KorC.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed.
DR   Gene3D; G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.
DR   Pfam; PF01558; POR; 1.
DR   TIGRFAMs; TIGR02175; PorC_KorC; 1.
PE   4: Predicted;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    185       Pyruvate/ketoisovalerate oxidoreductases
FT                                common subunit gamma.
FT                                /FTId=PRO_0000099915.
SQ   SEQUENCE   185 AA;  20051 MW;  99F746D9E801D0A6 CRC64;
     MIEIRFHGRG GQGAVTAANI LAEAAFLEGK YVQAFPFFGV ERRGAPVTAF TRIDEKPIRI
     KTQIYEPDIV VVLDPSLLET VDVTAGLKEE GIVIINTEKS KDEILEKLKK KPKKLALVDA
     TTIALETLGL PITNTAILGA VAKATGLVNI ESVEKAIKDT FSGELGEKNA KAAREAFEKT
     EIFEV
//