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O58411 (PORC_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma

Including the following 2 domains:

  1. Pyruvate synthase subunit porC
    EC=1.2.7.1
    Alternative name(s):
    Pyruvate oxidoreductase gamma chain
    Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit gamma
  2. Ketoisovalerate oxidoreductase subunit vorC
    Short name=VOR
    EC=1.2.7.7
    Alternative name(s):
    2-oxoisovalerate ferredoxin reductase subunit gamma
    2-oxoisovalerate oxidoreductase gamma chain
Gene names
Name:porG
Ordered Locus Names:PH0678
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.

3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.

Subunit structure

Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
PRO_0000099915

Sequences

Sequence LengthMass (Da)Tools
O58411 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 99F746D9E801D0A6

FASTA18520,051
        10         20         30         40         50         60 
MIEIRFHGRG GQGAVTAANI LAEAAFLEGK YVQAFPFFGV ERRGAPVTAF TRIDEKPIRI 

        70         80         90        100        110        120 
KTQIYEPDIV VVLDPSLLET VDVTAGLKEE GIVIINTEKS KDEILEKLKK KPKKLALVDA 

       130        140        150        160        170        180 
TTIALETLGL PITNTAILGA VAKATGLVNI ESVEKAIKDT FSGELGEKNA KAAREAFEKT 


EIFEV

« Hide

References

[1]"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3."
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. expand/collapse author list , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.
DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000001 Genomic DNA. Translation: BAA29769.1.
PIRG71113.
RefSeqNP_142628.1. NC_000961.1.

3D structure databases

ProteinModelPortalO58411.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000001177; EBPYRP00000001177; EBPYRG00000001177.
GeneID1443006.
GenomeReviewsGene locus PH0678 in contig BA000001_GR.
KEGGpho:PH0678.
NMPDRfig|70601.1.peg.659.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000022250.
HOGENOMHBG553299.
OMADYVIVQD.
ProtClustDBPRK14029.

Enzyme and pathway databases

BioCycPHOR70601:PH0678-MONOMER.

Family and domain databases

InterProIPR011894. PorC_KorC.
IPR019752. Pyrv/ketoisovalerate_OxRed_cat.
IPR002869. Pyrv_flavodox_OxRed_cen.
[Graphical view]
Gene3DG3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
KOK00189.
PfamPF01558. POR. 1 hit.
[Graphical view]
SUPFAMSSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
TIGRFAMsTIGR02175. PorC_KorC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePORC_PYRHO
AccessionPrimary (citable) accession number: O58411
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
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