ID   O58234_PYRHO            Unreviewed;       379 AA.
AC   O58234;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   RecName: Full=ATP-dependent DNA ligase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=PH0498 {ECO:0000313|EMBL:BAA29586.1};
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601 {ECO:0000313|EMBL:BAA29586.1, ECO:0000313|Proteomes:UP000000752};
RN   [1] {ECO:0000313|EMBL:BAA29586.1, ECO:0000313|Proteomes:UP000000752}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3
RC   {ECO:0000313|Proteomes:UP000000752};
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Nakamura Y.,
RA   Robb T.F., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
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DR   EMBL; BA000001; BAA29586.1; -; Genomic_DNA.
DR   PIR; E71162; E71162.
DR   RefSeq; WP_010884602.1; NC_000961.1.
DR   AlphaFoldDB; O58234; -.
DR   SMR; O58234; -.
DR   STRING; 70601.gene:9377432; -.
DR   EnsemblBacteria; BAA29586; BAA29586; BAA29586.
DR   GeneID; 1444389; -.
DR   KEGG; pho:PH0498; -.
DR   eggNOG; arCOG04218; Archaea.
DR   OrthoDB; 14524at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   CDD; cd07894; Adenylation_RNA_ligase; 1.
DR   Gene3D; 1.20.58.2250; -; 1.
DR   Gene3D; 3.10.450.740; -; 1.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.70.3360; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   InterPro; IPR041596; Lig_Pab1020_C.
DR   InterPro; IPR021122; RNA_ligase_dom_REL/Rnl2.
DR   InterPro; IPR001072; RNA_ligase_Pab1020.
DR   NCBIfam; TIGR01209; RNA ligase; 1.
DR   Pfam; PF18330; Lig_C; 1.
DR   Pfam; PF09414; RNA_ligase; 1.
DR   PRINTS; PR01048; Y414FAMILY.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
PE   4: Predicted;
FT   DOMAIN          86..240
FT                   /note="RNA ligase"
FT                   /evidence="ECO:0000259|Pfam:PF09414"
FT   DOMAIN          253..374
FT                   /note="RNA ligase Pab1020 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18330"
SQ   SEQUENCE   379 AA;  43959 MW;  195422B4A5641E29 CRC64;
     MVSSKFKDIL YRLGIPEGKV EDLEARGGLV EDKFDDIKYL RIRNSVGKLR RGTVVLNDKF
     IILGFPHIKR IVNLKNGIKR TFKRGEFYVE EKVDGYNVRV VKFRGKILGI TRGGFICPFT
     TERISDFIPE EFFKDHPNLI LVGEMAGPES PYLVEGPPYV KEDIQFFLFD IQELGTGRSL
     PVEERLKIAE EYGISHVEVF GKFTYKDLEE IYEIVERLSR EGREGIVMKS PDMRKMVKYV
     TPYANINDIK IGARVFYELP PGYFTSRISR LAFYIAEKRL RGENFEELAK ELGKALLQPL
     VESIHDVEQE DEIAEVFKVR VKKIETAYKM VTHFEKLGLR IEIVDIEEMK GGWRITFKRL
     YPDATEEIRE LIGGKSFVD
//