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Protein

Probable GTP-binding protein EngB

Gene

engB

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Necessary for normal cell division and for the maintenance of normal septation.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi41MagnesiumUniRule annotation1
Metal bindingi61MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi34 – 41GTPUniRule annotation8
Nucleotide bindingi59 – 63GTPUniRule annotation5
Nucleotide bindingi76 – 79GTPUniRule annotation4
Nucleotide bindingi156 – 159GTPUniRule annotation4
Nucleotide bindingi189 – 191GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Septation

Keywords - Ligandi

GTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable GTP-binding protein EngBUniRule annotation
Gene namesi
Name:engBUniRule annotation
Ordered Locus Names:PH0200
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001578141 – 216Probable GTP-binding protein EngBAdd BLAST216

Interactioni

Protein-protein interaction databases

STRINGi70601.PH0200.

Structurei

Secondary structure

1216
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi29 – 35Combined sources7
Helixi40 – 48Combined sources9
Beta strandi53 – 57Combined sources5
Beta strandi65 – 69Combined sources5
Beta strandi72 – 76Combined sources5
Helixi88 – 105Combined sources18
Helixi106 – 108Combined sources3
Beta strandi111 – 117Combined sources7
Helixi120 – 130Combined sources11
Helixi136 – 146Combined sources11
Beta strandi151 – 156Combined sources6
Helixi158 – 160Combined sources3
Helixi164 – 175Combined sources12
Helixi179 – 181Combined sources3
Helixi182 – 185Combined sources4
Beta strandi186 – 188Combined sources3
Turni191 – 193Combined sources3
Helixi197 – 210Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CXXX-ray1.70A/B/C27-216[»]
ProteinModelPortaliO57939.
SMRiO57939.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO57939.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 210EngB-type GUniRule annotationAdd BLAST185

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.UniRule annotation
Contains 1 EngB-type G (guanine nucleotide-binding) domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00355. Archaea.
COG0218. LUCA.
HOGENOMiHOG000227132.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00321. GTPase_EngB. 1 hit.
InterProiIPR030393. G_ENGB_dom.
IPR019987. GTP-bd_ribosome_bio_YsxC.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PfamiPF01926. MMR_HSR1. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51706. G_ENGB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O57939-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSTADSIF FFLPYEFINP IILLIPMATI IFAGRSNVGK STLIYRLTGK
60 70 80 90 100
KVRRGKRPGV TRKIIEIEWK NHKIIDMPGF GFMMGLPKEV QERIKDEIVH
110 120 130 140 150
FIEDNAKNID VAVLVVDGKA APEIIKRWEK RGEIPIDVEF YQFLRELDIP
160 170 180 190 200
TIVAVNKLDK IKNVQEVINF LAEKFEVPLS EIDKVFIPIS AKFGDNIERL
210
KNRIFEVIRE RQGRRV
Length:216
Mass (Da):25,051
Last modified:February 21, 2001 - v2
Checksum:i33B80F8B1A0E92E7
GO

Sequence cautioni

The sequence BAA29269 differs from that shown. Reason: Frameshift at several positions.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29269.1. Frameshift.
PIRiF71242.

Genome annotation databases

EnsemblBacteriaiBAA29269; BAA29269; BAA29269.
KEGGipho:PH0200.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29269.1. Frameshift.
PIRiF71242.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CXXX-ray1.70A/B/C27-216[»]
ProteinModelPortaliO57939.
SMRiO57939.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH0200.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA29269; BAA29269; BAA29269.
KEGGipho:PH0200.

Phylogenomic databases

eggNOGiarCOG00355. Archaea.
COG0218. LUCA.
HOGENOMiHOG000227132.

Miscellaneous databases

EvolutionaryTraceiO57939.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00321. GTPase_EngB. 1 hit.
InterProiIPR030393. G_ENGB_dom.
IPR019987. GTP-bd_ribosome_bio_YsxC.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PfamiPF01926. MMR_HSR1. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51706. G_ENGB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiENGB_PYRHO
AccessioniPrimary (citable) accession number: O57939
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: February 21, 2001
Last modified: November 30, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.