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Protein

Putative 1-aminocyclopropane-1-carboxylate deaminase

Gene

PH0054

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3.

Cofactori

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-52-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative 1-aminocyclopropane-1-carboxylate deaminase (EC:3.5.99.7)
Short name:
ACC deaminase
Gene namesi
Ordered Locus Names:PH0054
ORF Names:PHBE027
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001845231 – 325Putative 1-aminocyclopropane-1-carboxylate deaminaseAdd BLAST325

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei54N6-(pyridoxal phosphate)lysineBy similarity1

Interactioni

Protein-protein interaction databases

STRINGi70601.PH0054.

Structurei

Secondary structure

1325
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 9Combined sources7
Beta strandi24 – 26Combined sources3
Helixi28 – 34Combined sources7
Beta strandi36 – 42Combined sources7
Helixi43 – 45Combined sources3
Beta strandi46 – 48Combined sources3
Helixi54 – 67Combined sources14
Beta strandi71 – 76Combined sources6
Helixi82 – 93Combined sources12
Beta strandi97 – 104Combined sources8
Helixi110 – 117Combined sources8
Beta strandi121 – 126Combined sources6
Turni130 – 132Combined sources3
Helixi133 – 144Combined sources12
Beta strandi151 – 154Combined sources4
Helixi156 – 158Combined sources3
Helixi161 – 164Combined sources4
Helixi166 – 177Combined sources12
Beta strandi183 – 192Combined sources10
Helixi193 – 204Combined sources12
Beta strandi210 – 215Combined sources6
Beta strandi220 – 222Combined sources3
Helixi223 – 237Combined sources15
Beta strandi247 – 250Combined sources4
Helixi261 – 274Combined sources14
Turni280 – 282Combined sources3
Helixi283 – 295Combined sources13
Turni296 – 299Combined sources4
Beta strandi301 – 307Combined sources7
Helixi311 – 316Combined sources6
Helixi318 – 322Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1J0AX-ray2.50A/B/C1-325[»]
1J0BX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-325[»]
ProteinModelPortaliO57809.
SMRiO57809.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO57809.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG01435. Archaea.
COG2515. LUCA.
HOGENOMiHOG000022459.
KOiK01505.
OMAiTLWDDYF.

Family and domain databases

InterProiIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01275. ACC_deam_rel. 1 hit.

Sequencei

Sequence statusi: Complete.

O57809-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPKIFALLA KFPRVELIPW ETPIQYLPNI SREIGADVYI KRDDLTGLGI
60 70 80 90 100
GGNKIRKLEY LLGDALSKGA DVVITVGAVH SNHAFVTGLA AKKLGLDAIL
110 120 130 140 150
VLRGKEELKG NYLLDKIMGI ETRVYDAKDS FELMKYAEEI AEELKREGRK
160 170 180 190 200
PYVIPPGGAS PIGTLGYVRA VGEIATQSEV KFDSIVVAAG SGGTLAGLSL
210 220 230 240 250
GLSILNEDIR PVGIAVGRFG EVMTSKLDNL IKEAAELLGV KVEVRPELYD
260 270 280 290 300
YSFGEYGKIT GEVAQIIRKV GTREGIILDP VYTGKAFYGL VDLARKGELG
310 320
EKILFIHTGG ISGTFHYGDK LLSLL
Length:325
Mass (Da):35,188
Last modified:May 30, 2000 - v2
Checksum:i60AE1B7A37CDF231
GO

Sequence cautioni

The sequence BAA29122 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29122.1. Different initiation.
PIRiC71224.
RefSeqiWP_010884169.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA29122; BAA29122; BAA29122.
GeneIDi1443951.
KEGGipho:PH0054.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29122.1. Different initiation.
PIRiC71224.
RefSeqiWP_010884169.1. NC_000961.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1J0AX-ray2.50A/B/C1-325[»]
1J0BX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-325[»]
ProteinModelPortaliO57809.
SMRiO57809.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH0054.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA29122; BAA29122; BAA29122.
GeneIDi1443951.
KEGGipho:PH0054.

Phylogenomic databases

eggNOGiarCOG01435. Archaea.
COG2515. LUCA.
HOGENOMiHOG000022459.
KOiK01505.
OMAiTLWDDYF.

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-52-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO57809.

Family and domain databases

InterProiIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01275. ACC_deam_rel. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry namei1A1D_PYRHO
AccessioniPrimary (citable) accession number: O57809
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: May 30, 2000
Last modified: November 2, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.