Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative 1-aminocyclopropane-1-carboxylate deaminase

Gene

PH0054

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3.

Cofactori

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-52-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative 1-aminocyclopropane-1-carboxylate deaminase (EC:3.5.99.7)
Short name:
ACC deaminase
Gene namesi
Ordered Locus Names:PH0054
ORF Names:PHBE027
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 325325Putative 1-aminocyclopropane-1-carboxylate deaminasePRO_0000184523Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei54 – 541N6-(pyridoxal phosphate)lysineBy similarity

Interactioni

Protein-protein interaction databases

STRINGi70601.PH0054.

Structurei

Secondary structure

1
325
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 97Combined sources
Beta strandi24 – 263Combined sources
Helixi28 – 347Combined sources
Beta strandi36 – 427Combined sources
Helixi43 – 453Combined sources
Beta strandi46 – 483Combined sources
Helixi54 – 6714Combined sources
Beta strandi71 – 766Combined sources
Helixi82 – 9312Combined sources
Beta strandi97 – 1048Combined sources
Helixi110 – 1178Combined sources
Beta strandi121 – 1266Combined sources
Turni130 – 1323Combined sources
Helixi133 – 14412Combined sources
Beta strandi151 – 1544Combined sources
Helixi156 – 1583Combined sources
Helixi161 – 1644Combined sources
Helixi166 – 17712Combined sources
Beta strandi183 – 19210Combined sources
Helixi193 – 20412Combined sources
Beta strandi210 – 2156Combined sources
Beta strandi220 – 2223Combined sources
Helixi223 – 23715Combined sources
Beta strandi247 – 2504Combined sources
Helixi261 – 27414Combined sources
Turni280 – 2823Combined sources
Helixi283 – 29513Combined sources
Turni296 – 2994Combined sources
Beta strandi301 – 3077Combined sources
Helixi311 – 3166Combined sources
Helixi318 – 3225Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J0AX-ray2.50A/B/C1-325[»]
1J0BX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-325[»]
ProteinModelPortaliO57809.
SMRiO57809. Positions 1-325.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO57809.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG01435. Archaea.
COG2515. LUCA.
HOGENOMiHOG000022459.
KOiK01505.
OMAiTLWDDYF.

Family and domain databases

InterProiIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01275. ACC_deam_rel. 1 hit.

Sequencei

Sequence statusi: Complete.

O57809-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPKIFALLA KFPRVELIPW ETPIQYLPNI SREIGADVYI KRDDLTGLGI
60 70 80 90 100
GGNKIRKLEY LLGDALSKGA DVVITVGAVH SNHAFVTGLA AKKLGLDAIL
110 120 130 140 150
VLRGKEELKG NYLLDKIMGI ETRVYDAKDS FELMKYAEEI AEELKREGRK
160 170 180 190 200
PYVIPPGGAS PIGTLGYVRA VGEIATQSEV KFDSIVVAAG SGGTLAGLSL
210 220 230 240 250
GLSILNEDIR PVGIAVGRFG EVMTSKLDNL IKEAAELLGV KVEVRPELYD
260 270 280 290 300
YSFGEYGKIT GEVAQIIRKV GTREGIILDP VYTGKAFYGL VDLARKGELG
310 320
EKILFIHTGG ISGTFHYGDK LLSLL
Length:325
Mass (Da):35,188
Last modified:May 30, 2000 - v2
Checksum:i60AE1B7A37CDF231
GO

Sequence cautioni

The sequence BAA29122 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29122.1. Different initiation.
PIRiC71224.
RefSeqiWP_010884169.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA29122; BAA29122; BAA29122.
GeneIDi1443951.
KEGGipho:PH0054.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29122.1. Different initiation.
PIRiC71224.
RefSeqiWP_010884169.1. NC_000961.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J0AX-ray2.50A/B/C1-325[»]
1J0BX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-325[»]
ProteinModelPortaliO57809.
SMRiO57809. Positions 1-325.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH0054.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA29122; BAA29122; BAA29122.
GeneIDi1443951.
KEGGipho:PH0054.

Phylogenomic databases

eggNOGiarCOG01435. Archaea.
COG2515. LUCA.
HOGENOMiHOG000022459.
KOiK01505.
OMAiTLWDDYF.

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-52-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO57809.

Family and domain databases

InterProiIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01275. ACC_deam_rel. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry namei1A1D_PYRHO
AccessioniPrimary (citable) accession number: O57809
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: May 30, 2000
Last modified: November 11, 2015
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.