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Protein
Submitted name:

373aa long hypothetical sugar-binding transport ATP-binding protein

Gene

PH0022

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei22 – 221ATPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi46 – 538ATPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationCombined sourcesImported, Nucleotide-binding

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-24-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
373aa long hypothetical sugar-binding transport ATP-binding proteinImported
Gene namesi
Ordered Locus Names:PH0022Imported
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)Imported
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi70601.PH0022.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1V43X-ray2.20A2-373[»]
1VCIX-ray2.90A1-373[»]
ProteinModelPortaliO57758.
SMRiO57758. Positions 7-373.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO57758.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 243231ABC transporterInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00175. Archaea.
COG3839. LUCA.
KOiK10112.
OMAiAPELTIH.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR013611. Transp-assoc_OB_typ2.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08402. TOBE_2. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O57758-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNNIEVIKM VEVKLENLTK RFGNFTAVNK LNLTIKDGEF LVLLGPSGCG
60 70 80 90 100
KTTTLRMIAG LEEPTEGRIY FGDRDVTYLP PKDRNISMVF QSYAVWPHMT
110 120 130 140 150
VYENIAFPLK IKKFPKDEID KRVRWAAELL QIEELLNRYP AQLSGGQRQR
160 170 180 190 200
VAVARAIVVE PDVLLMDEPL SNLDAKLRVA MRAEIKKLQQ KLKVTTIYVT
210 220 230 240 250
HDQVEAMTMG DRIAVMNRGQ LLQIGSPTEV YLRPNSVFVA TFIGAPEMNI
260 270 280 290 300
LEVSVGDGYL EGRGFRIELP QDLMDLLKDY VGKTVLFGIR PEHMTVEGVS
310 320 330 340 350
ELAHMKRTAR LIGKVDFVEA LGTDTILHVK FGDELVKVKL PGHIPIEPGR
360 370
EVKVIMDLDM IHVFDKDTEK AIV
Length:373
Mass (Da):42,071
Last modified:August 1, 1998 - v1
Checksum:i583DFDCF3B5764BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29090.1.
PIRiC71220.

Genome annotation databases

EnsemblBacteriaiBAA29090; BAA29090; BAA29090.
KEGGipho:PH0022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA29090.1.
PIRiC71220.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1V43X-ray2.20A2-373[»]
1VCIX-ray2.90A1-373[»]
ProteinModelPortaliO57758.
SMRiO57758. Positions 7-373.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH0022.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA29090; BAA29090; BAA29090.
KEGGipho:PH0022.

Phylogenomic databases

eggNOGiarCOG00175. Archaea.
COG3839. LUCA.
KOiK10112.
OMAiAPELTIH.

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-24-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO57758.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR013611. Transp-assoc_OB_typ2.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08402. TOBE_2. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3Imported.
  2. "Crystal structure of the ATP-binding cassette of multisugar transporter from Pyrococcus horikoshii OT3."
    Ose T., Fujie T., Yao M., Watanabe N., Tanaka I.
    Proteins 57:635-638(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 2-373 IN COMPLEX WITH ATP.

Entry informationi

Entry nameiO57758_PYRHO
AccessioniPrimary (citable) accession number: O57758
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: April 13, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.