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O57706

- DCD_PYRHO

UniProt

O57706 - DCD_PYRHO

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Protein
Probable deoxycytidine triphosphate deaminase
Gene
dcd, PH1997
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1999-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:PH1997
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000752: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 156156Probable deoxycytidine triphosphate deaminaseUniRule annotation
PRO_0000156037Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1997.

Structurei

3D structure databases

ProteinModelPortaliO57706.

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228601.
KOiK01494.
OMAiGSFAWVD.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

O57706-1 [UniParc]FASTAAdd to Basket

« Hide

MLLPDWKIRK EILIEPFSEE SLQPAGYDLR VGREAFVSGK LIDVEKEGKV    50
VIPPREYALI LTLERVKLPD DVMGDMKIRS SLAREGILGS FAWVDPGWDG 100
NLTLMLYNAS NEPVELKYGE RFVQIVFIRL EDPPRNPYSG NYQGSTRLVF 150
SKRKKL 156
Length:156
Mass (Da):17,871
Last modified:August 1, 1998 - v1
Checksum:i96B2C2C50393A985
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000001 Genomic DNA. Translation: BAA31124.1.
PIRiE71216.
RefSeqiNP_143819.1. NC_000961.1.
WP_010886058.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA31124; BAA31124; BAA31124.
GeneIDi1442840.
KEGGipho:PH1997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000001 Genomic DNA. Translation: BAA31124.1 .
PIRi E71216.
RefSeqi NP_143819.1. NC_000961.1.
WP_010886058.1. NC_000961.1.

3D structure databases

ProteinModelPortali O57706.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 70601.PH1997.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA31124 ; BAA31124 ; BAA31124 .
GeneIDi 1442840.
KEGGi pho:PH1997.

Phylogenomic databases

eggNOGi COG0717.
HOGENOMi HOG000228601.
KOi K01494.
OMAi GSFAWVD.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci PHOR70601:GJWR-1999-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

Entry informationi

Entry nameiDCD_PYRHO
AccessioniPrimary (citable) accession number: O57706
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: September 3, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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