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O57706

- DCD_PYRHO

UniProt

O57706 - DCD_PYRHO

Protein

Probable deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Aug 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    dCTP + H2O = dUTP + NH3.

    Pathwayi

    GO - Molecular functioni

    1. dCTP deaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. dUMP biosynthetic process Source: UniProtKB-UniPathway
    2. dUTP biosynthetic process Source: InterPro
    3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Nucleotide metabolism

    Enzyme and pathway databases

    BioCyciPHOR70601:GJWR-1999-MONOMER.
    UniPathwayiUPA00610; UER00665.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable deoxycytidine triphosphate deaminase (EC:3.5.4.13)
    Short name:
    dCTP deaminase
    Gene namesi
    Name:dcd
    Ordered Locus Names:PH1997
    OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
    Taxonomic identifieri70601 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
    ProteomesiUP000000752: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 156156Probable deoxycytidine triphosphate deaminasePRO_0000156037Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi70601.PH1997.

    Structurei

    3D structure databases

    ProteinModelPortaliO57706.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the dCTP deaminase family.Curated

    Phylogenomic databases

    eggNOGiCOG0717.
    HOGENOMiHOG000228601.
    KOiK01494.
    OMAiGSFAWVD.

    Family and domain databases

    Gene3Di2.70.40.10. 1 hit.
    HAMAPiMF_00146. dCTP_deaminase.
    InterProiIPR011962. dCTP_deam.
    IPR029054. dUTPase-like.
    IPR008180. dUTPase/dCTP_deaminase.
    [Graphical view]
    PfamiPF00692. dUTPase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51283. SSF51283. 1 hit.
    TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O57706-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLPDWKIRK EILIEPFSEE SLQPAGYDLR VGREAFVSGK LIDVEKEGKV    50
    VIPPREYALI LTLERVKLPD DVMGDMKIRS SLAREGILGS FAWVDPGWDG 100
    NLTLMLYNAS NEPVELKYGE RFVQIVFIRL EDPPRNPYSG NYQGSTRLVF 150
    SKRKKL 156
    Length:156
    Mass (Da):17,871
    Last modified:August 1, 1998 - v1
    Checksum:i96B2C2C50393A985
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000001 Genomic DNA. Translation: BAA31124.1.
    PIRiE71216.
    RefSeqiNP_143819.1. NC_000961.1.
    WP_010886058.1. NC_000961.1.

    Genome annotation databases

    EnsemblBacteriaiBAA31124; BAA31124; BAA31124.
    GeneIDi1442840.
    KEGGipho:PH1997.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000001 Genomic DNA. Translation: BAA31124.1 .
    PIRi E71216.
    RefSeqi NP_143819.1. NC_000961.1.
    WP_010886058.1. NC_000961.1.

    3D structure databases

    ProteinModelPortali O57706.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 70601.PH1997.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA31124 ; BAA31124 ; BAA31124 .
    GeneIDi 1442840.
    KEGGi pho:PH1997.

    Phylogenomic databases

    eggNOGi COG0717.
    HOGENOMi HOG000228601.
    KOi K01494.
    OMAi GSFAWVD.

    Enzyme and pathway databases

    UniPathwayi UPA00610 ; UER00665 .
    BioCyci PHOR70601:GJWR-1999-MONOMER.

    Family and domain databases

    Gene3Di 2.70.40.10. 1 hit.
    HAMAPi MF_00146. dCTP_deaminase.
    InterProi IPR011962. dCTP_deam.
    IPR029054. dUTPase-like.
    IPR008180. dUTPase/dCTP_deaminase.
    [Graphical view ]
    Pfami PF00692. dUTPase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51283. SSF51283. 1 hit.
    TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

    Entry informationi

    Entry nameiDCD_PYRHO
    AccessioniPrimary (citable) accession number: O57706
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: August 1, 1998
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3