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O57706

- DCD_PYRHO

UniProt

O57706 - DCD_PYRHO

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Protein

Probable deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1999-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:PH1997
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000752: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 156156Probable deoxycytidine triphosphate deaminasePRO_0000156037Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1997.

Structurei

3D structure databases

ProteinModelPortaliO57706.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.Curated

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228601.
KOiK01494.
OMAiGSFAWVD.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

O57706-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLPDWKIRK EILIEPFSEE SLQPAGYDLR VGREAFVSGK LIDVEKEGKV
60 70 80 90 100
VIPPREYALI LTLERVKLPD DVMGDMKIRS SLAREGILGS FAWVDPGWDG
110 120 130 140 150
NLTLMLYNAS NEPVELKYGE RFVQIVFIRL EDPPRNPYSG NYQGSTRLVF

SKRKKL
Length:156
Mass (Da):17,871
Last modified:August 1, 1998 - v1
Checksum:i96B2C2C50393A985
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA31124.1.
PIRiE71216.
RefSeqiNP_143819.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA31124; BAA31124; BAA31124.
GeneIDi1442840.
KEGGipho:PH1997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA31124.1 .
PIRi E71216.
RefSeqi NP_143819.1. NC_000961.1.

3D structure databases

ProteinModelPortali O57706.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 70601.PH1997.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA31124 ; BAA31124 ; BAA31124 .
GeneIDi 1442840.
KEGGi pho:PH1997.

Phylogenomic databases

eggNOGi COG0717.
HOGENOMi HOG000228601.
KOi K01494.
OMAi GSFAWVD.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci PHOR70601:GJWR-1999-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

Entry informationi

Entry nameiDCD_PYRHO
AccessioniPrimary (citable) accession number: O57706
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: November 26, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3