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Protein

POU domain protein

Gene

Pit1W*

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Pit1W*Imported
Synonyms:Pit-1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000024943.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini159 – 23375POU-specificInterPro annotationAdd
BLAST
Domaini247 – 30761Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
HOGENOMiHOG000116302.
HOVERGENiHBG053120.
KOiK09363.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR015586. Pit_1.
IPR013847. POU.
IPR000327. POU_dom.
[Graphical view]
PANTHERiPTHR11636:SF84. PTHR11636:SF84. 1 hit.
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O57599-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLESSCIFL PVPSVLSLIQ TPKCSHLHFA MMTSGNVSAG LHYSVPSCHY
60 70 80 90 100
GNQASTYGVM AGIKPATPEM LSASLSQSRI LQTCSMPHPN VVNGVSTLQS
110 120 130 140 150
SLTPCLYKFP EHALSASSCA LGHSFTPMHQ TLLSDDPTAS DFKQEFRRKS
160 170 180 190 200
KSVEEPVDMD SPEIRELEKF ANEFKLRRIK LGYTQTNVGE ALAAVHGSEF
210 220 230 240 250
SQTTICRFEN LQLSFKNACK LKSILSKWLE EAEQVGALYN EKVGVNERKR
260 270 280 290 300
KRRTTISISA KEALERHFGE QSKPSSQEIM RMAEGLNLEK EVVRVWFCNR
310 320
RQREKRVKTS LHQNAFSSII KEHHECR
Length:327
Mass (Da):36,802
Last modified:May 1, 1999 - v3
Checksum:iB3997E017BD1C3D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF029892 mRNA. Translation: AAD01888.1.
AJ222692 mRNA. Translation: CAA10947.2.
RefSeqiNP_989650.1. NM_204319.1.
UniGeneiGga.213.
Gga.56300.
Gga.56304.

Genome annotation databases

GeneIDi374215.
KEGGigga:374215.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF029892 mRNA. Translation: AAD01888.1.
AJ222692 mRNA. Translation: CAA10947.2.
RefSeqiNP_989650.1. NM_204319.1.
UniGeneiGga.213.
Gga.56300.
Gga.56304.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000024943.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi374215.
KEGGigga:374215.

Organism-specific databases

CTDi5449.

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
HOGENOMiHOG000116302.
HOVERGENiHBG053120.
KOiK09363.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR015586. Pit_1.
IPR013847. POU.
IPR000327. POU_dom.
[Graphical view]
PANTHERiPTHR11636:SF84. PTHR11636:SF84. 1 hit.
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Tanaka M., Yamamoto I., Ohkubo T., Wakita M., Hoshino S., Nakashima K.
    Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White LeghornImported.
  2. Van As P.
    Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: RossImported.
    Tissue: PituitaryImported.
  3. "Complementary DNA cloning and ontogenic expression of pituitary-specific transcription factor of chickens (Gallus domesticus) from the pituitary gland."
    Van As P., Buys N., Onagbesan O.M., Decuypere E.
    Gen. Comp. Endocrinol. 120:127-136(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: RossImported.
    Tissue: PituitaryImported.
  4. "A new single nucleotide polymorphism in the chicken pituitary-specific transcription factor (POU1F1) gene associated with growth rate."
    Jiang R., Li J., Qu L., Li H., Yang N.
    Anim. Genet. 35:344-346(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White LeghornImported.

Entry informationi

Entry nameiO57599_CHICK
AccessioniPrimary (citable) accession number: O57599
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: May 1, 1999
Last modified: July 6, 2016
This is version 119 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.