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Protein

POU domain protein

Gene

Pit1W*

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi249 – 308HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Pit1W*Imported
Synonyms:Pit-1Imported, POU1F1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000015495.
ExpressionAtlasiO57599. baseline.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 233POU-specificInterPro annotationAdd BLAST75
Domaini247 – 307HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.
HOGENOMiHOG000116302.
HOVERGENiHBG053120.
OrthoDBiEOG091G0U0S.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom_sf.
IPR015586. Pit_1.
IPR013847. POU.
IPR000327. POU_dom.
PANTHERiPTHR11636:SF84. PTHR11636:SF84. 1 hit.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

O57599-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLESSCIFL PVPSVLSLIQ TPKCSHLHFA MMTSGNVSAG LHYSVPSCHY
60 70 80 90 100
GNQASTYGVM AGIKPATPEM LSASLSQSRI LQTCSMPHPN VVNGVSTLQS
110 120 130 140 150
SLTPCLYKFP EHALSASSCA LGHSFTPMHQ TLLSDDPTAS DFKQEFRRKS
160 170 180 190 200
KSVEEPVDMD SPEIRELEKF ANEFKLRRIK LGYTQTNVGE ALAAVHGSEF
210 220 230 240 250
SQTTICRFEN LQLSFKNACK LKSILSKWLE EAEQVGALYN EKVGVNERKR
260 270 280 290 300
KRRTTISISA KEALERHFGE QSKPSSQEIM RMAEGLNLEK EVVRVWFCNR
310 320
RQREKRVKTS LHQNAFSSII KEHHECR
Length:327
Mass (Da):36,802
Last modified:May 1, 1999 - v3
Checksum:iB3997E017BD1C3D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000152 Genomic DNA. No translation available.
AF029892 mRNA. Translation: AAD01888.1.
AJ222692 mRNA. Translation: CAA10947.2.
RefSeqiNP_989650.1. NM_204319.1.
UniGeneiGga.213.
Gga.56300.
Gga.56304.

Genome annotation databases

EnsembliENSGALT00000036836; ENSGALP00000036048; ENSGALG00000015495.
GeneIDi374215.

Similar proteinsi

Entry informationi

Entry nameiO57599_CHICK
AccessioniPrimary (citable) accession number: O57599
Secondary accession number(s): F1NRJ0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: May 1, 1999
Last modified: November 22, 2017
This is version 134 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported