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Protein
Submitted name:

NCAM-140

Gene
N/A
Organism
Cynops pyrrhogaster (Japanese fire-bellied newt)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NCAM-140Imported
OrganismiCynops pyrrhogaster (Japanese fire-bellied newt)Imported
Taxonomic identifieri8330 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaCaudataSalamandroideaSalamandridaePleurodelinaeCynops

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei711 – 73424HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 846827Sequence analysisPRO_5004159091Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO57577.
SMRiO57577. Positions 20-304.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 11293Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini115 – 19985Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini211 – 29686Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini305 – 40096Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini403 – 49290Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini496 – 595100Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini598 – 69598Fibronectin type-IIIInterPro annotationAdd
BLAST

Keywords - Domaini

Immunoglobulin domainUniRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG052579.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013151. Immunoglobulin.
IPR033019. Ncam1.
IPR009138. Neural_cell_adh.
[Graphical view]
PANTHERiPTHR10489:SF34. PTHR10489:SF34. 1 hit.
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 3 hits.
PF00047. ig. 1 hit.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O57577-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQTQELIWT WLLLGTAVCI QVTVVPSQVD VDVGESKFFS CQVTGGEAKD
60 70 80 90 100
IFWFSPSGEK ISANQQEISI VRNDEVSSTL SIYNVDIDDA GIYKCVVTTE
110 120 130 140 150
GEGEMEATVN VQIYQKMVFR NAPSPQEFTE GEDAVVVCDV VSVQTPSVMW
160 170 180 190 200
KHKGRDVVLK KDVRFVVLAN NYLQIRGIKK TDEGMYRCEG RIQARGEIAF
210 220 230 240 250
KDIQVVVNVA PSVRARQTTV NATANLGEAA VLACDADGFP DPEISWTKDG
260 270 280 290 300
EMIEDDSDKY KFTEDGSEMT IFNIDKSDEG DYTCIAENKA GEQEASILLK
310 320 330 340 350
VYAKPKITYV ENKTAMELEE QITLTCEASG DPTPSITWRM ATRNISSDEK
360 370 380 390 400
TLDGRIVVSS HARVSSLTLN DIQYTDAGEY LCIGSNTIGQ DSQAMYLEVQ
410 420 430 440 450
YAPKLQGPVA VYTWEGNAVN ITCEVFAYPS AVVSWFRDGQ ALPSSNYSNI
460 470 480 490 500
KIYSTPSASF LEVVPDSEND FGNYNCTAVN RIGQESSEFI LVPADTPSSP
510 520 530 540 550
SILKLEPYSS SAKMEFDEPD ATGGVPILKY RAEWKVLGEG EWSSRMYDAK
560 570 580 590 600
EASIENAITI VGLKPETVYA VRLSAINGKG LGEYSPVSEF KTEPVQGEPS
610 620 630 640 650
APKLDGQIGE DGKSIRINLI KQDDGGSPIR HYLYTYRAKN ALEWSPETRV
660 670 680 690 700
PSVSNHFTLK SLAWNAEYEV SVIAENLQGK SKPARFTFKT LFEPTAIPAG
710 720 730 740 750
PSSGSGLGTG AIVGILIIVF VILLVVVDVT CYFLNKCGLL MCIAVNLCGK
760 770 780 790 800
SGPGAKGKDI EEGKAAFSKD ESKEPIVEVR TEEERTPNHD GGNQTEPNET
810 820 830 840
TPLTEPEKAP VEENSKPEDT EAKTTAPEVK TIPNNATQTN ENESKA
Length:846
Mass (Da):92,545
Last modified:June 1, 1998 - v1
Checksum:i59D599C035A1DDB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85084 mRNA. Translation: BAA24033.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85084 mRNA. Translation: BAA24033.1.

3D structure databases

ProteinModelPortaliO57577.
SMRiO57577. Positions 20-304.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG052579.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013151. Immunoglobulin.
IPR033019. Ncam1.
IPR009138. Neural_cell_adh.
[Graphical view]
PANTHERiPTHR10489:SF34. PTHR10489:SF34. 1 hit.
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 3 hits.
PF00047. ig. 1 hit.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "pax-6 gene expression in newt eye development."
    Mizuno M., Takabatake T., Takahashi T.C., Takeshima K.
    Dev. Genes Evol. 207:167-176(1997)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiO57577_CYNPY
AccessioniPrimary (citable) accession number: O57577
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: July 6, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.