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Protein
Submitted name:

Paired box 3a

Gene

pax3a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi220 – 279HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

  • developmental pigmentation Source: ZFIN
  • enteric nervous system development Source: ZFIN
  • neural crest cell migration Source: ZFIN
  • regulation of transcription, DNA-templated Source: UniProtKB-UniRule
  • transcription, DNA-templated Source: UniProtKB-UniRule
  • xanthophore differentiation Source: ZFIN

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-3214847 HATs acetylate histones

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box 3aImported
Submitted name:
Transcription factor PAX3Imported
Gene namesi
Name:pax3aImported
Synonyms:pax3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-980526-52 pax3a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000010192

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000037761

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 161PairedInterPro annotationAdd BLAST128
Domaini218 – 278HomeoboxInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotation, Paired boxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0849 Eukaryota
ENOG410XS01 LUCA
GeneTreeiENSGT00680000099553
HOGENOMiHOG000230939
HOVERGENiHBG009115
KOiK09381
OrthoDBiEOG091G0S4E
TreeFamiTF351610

Family and domain databases

CDDicd00086 homeodomain, 1 hit
cd00131 PAX, 1 hit
Gene3Di1.10.10.10, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR001523 Paired_dom
IPR022106 Pax7_C
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00292 PAX, 1 hit
PF12360 Pax7, 1 hit
PRINTSiPR00027 PAIREDBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00351 PAX, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00034 PAIRED_1, 1 hit
PS51057 PAIRED_2, 1 hit

Sequencei

Sequence statusi: Complete.

O57416-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTALAGGISR MMRPTPPQNY PRGGYSLEVS TPLGQGRVNQ LGGVFINGRP
60 70 80 90 100
LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA
110 120 130 140 150
IGGSKPKQST TPDVEKKIEE YKRENPGMFS WEIRDKLLKD GICDRNNVPS
160 170 180 190 200
VSSISRMLRC KFGGNGDEDE DDDEVEKREI EENERRAKHS IDGILGDRSS
210 220 230 240 250
HSDEGSDVDS EPGLPLKRKQ RRSRTTFTAE QLEELERAFE RTHYPDIYTR
260 270 280 290 300
EELAQRAKLT EARVQVWFSN RRARWRKQAG ANQLMAFNHL IPGGFPPSAM
310 320 330 340 350
SSLQPYQLAD SPYPPSSISQ VSEQPSTVHR PQPLPPTSVH QSGLGSGPGA
360 370 380 390 400
QEGSSAYCLS SGRHGFSGYS DGYVAAPGHA NPVNPSISNG LPSQVMGLLN
410 420 430 440 450
PGAVPHQPQS DFALSPLTGG LEPSTGMPAS CHSSQRLEAL PGLPSMPALP
460 470 480 490 500
SSQSYCPSSY SSPGYSVDHV ASYQYSQYGQ SKVNTSTVTT VERLSRVYPL

KRASFGLVE
Length:509
Mass (Da):55,671
Last modified:June 1, 1998 - v1
Checksum:i44F67FC287617F1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX085193 Genomic DNA No translation available.
AF014366 mRNA Translation: AAC41253.1
RefSeqiNP_571352.1, NM_131277.1
UniGeneiDr.75806

Genome annotation databases

EnsembliENSDART00000038828; ENSDARP00000037761; ENSDARG00000010192
GeneIDi30532
KEGGidre:30532

Similar proteinsi

Entry informationi

Entry nameiO57416_DANRE
AccessioniPrimary (citable) accession number: O57416
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: June 20, 2018
This is version 156 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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