Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ras-responsive element-binding protein 1

Gene

RREB1

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri47 – 69C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri78 – 100C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri106 – 128C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri189 – 211C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 239C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri297 – 319C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri622 – 644C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri650 – 672C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri732 – 754C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri763 – 788C2H2-type 10PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri1170 – 1192C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1298 – 1320C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1419 – 1441C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1447 – 1469C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-responsive element-binding protein 1
Short name:
RREB-1
Gene namesi
Name:RREB1
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002951561 – 1615Ras-responsive element-binding protein 1Add BLAST1615

Proteomic databases

PaxDbiO57415
PRIDEiO57415

Expressioni

Tissue specificityi

Broadly expressed, except in brain.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000020854

Structurei

3D structure databases

ProteinModelPortaliO57415
SMRiO57415
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi463 – 528Pro-richAdd BLAST66

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri47 – 69C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri78 – 100C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri106 – 128C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri189 – 211C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 239C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri297 – 319C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri622 – 644C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri650 – 672C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri732 – 754C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri763 – 788C2H2-type 10PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri1170 – 1192C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1298 – 1320C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1419 – 1441C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri1447 – 1469C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000154195
HOVERGENiHBG108418
InParanoidiO57415
KOiK20210
PhylomeDBiO57415

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits

Sequencei

Sequence statusi: Complete.

O57415-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSAVMNVGK IAENGGTSQT VKSPSKSPAP NRIGRRNQET KEEKSSYTCP
60 70 80 90 100
LCEKICTTQH QLTMHIRQHN TDTGGTDHSC SICGKSLSSA SSLDRHMLVH
110 120 130 140 150
SGERPYKCSV CGQSFTTNGN MHRHMKIHEK DPNSTASTTP PSPLKAKRLS
160 170 180 190 200
SKRKFSQDAE MDREERTPAK KVVEDGQYGE GDRKEDDAYH CPVCFKDFFC
210 220 230 240 250
KYALESHMET HPDNSLRCDI CCITFRTHRG LLRHNAVIHK QLPRDPTGKP
260 270 280 290 300
FIQNNPSIPA GFHDLGFTDF SCRKFPRISQ VWCETNLRRC ISEFHRFICE
310 320 330 340 350
TCNKAFPMLL ALKLHTETHV MDQGRDKHKL QSTSLPSENP DQKAFMASLG
360 370 380 390 400
LQYTKDIKPV KQEDDTQDEV QEMRLRALKS NLPQEPGSTG LLSLSPLEAA
410 420 430 440 450
TMGGPFSVLP PTKENIKLLS LQPFQKGFII QPDSSIVVKP ISNESAIELA
460 470 480 490 500
DIQQILKMAS SAPPQISLPP LSKAPSVPVQ SIFKHMPPLK PKPLVTPRTV
510 520 530 540 550
VATSTPPPLI SAQQASPGCI SPSLPPPPLR LIKNSVETSS NSHLSQPGAK
560 570 580 590 600
SSPSSQLLLQ PKVEPLTQHE MKTQLEQDSI IEALLPLNME AKIKQEVTEG
610 620 630 640 650
DLKAIIAGAA NKKAPTMRKV LYPCRFCDQV FAFSGVLRAH IRSHLGISPY
660 670 680 690 700
QCNICDYIAA DKAALIRHLR THSGERPYIC KICHYPGTVK ANCERHLRKK
710 720 730 740 750
HLKVTRKDIE KNIEYVTSNA AEMVDAFCSP DTVCKLCGED LKHYRALRIH
760 770 780 790 800
MRTHSGCQKK KPFECKECGT AFSAKRNCIH HILKQHLHVQ EREIENYILV
810 820 830 840 850
VDCSAQESHT DAPLLEDSTY MDCKPITPFL EPQNGFLLGT SSHVPIKLEP
860 870 880 890 900
MGNFPMDFDE PLDFSQKSKN LSAVQVKQEN LLVSSPLSFY DCSMEPIDLS
910 920 930 940 950
IPKVLKRDND IPGEARNQEL ASSVITDNAY NWQQCPLGFG ANGNSEKNRA
960 970 980 990 1000
VGHPQPLKGS LHLTVPIISP ALLGNSALLR PLRPKPPPQP LLPKPPVTKE
1010 1020 1030 1040 1050
LPPLASIAQI ISSVSSAPAL LKTEAADASP KAASSSTGCD KSGNAKAKMT
1060 1070 1080 1090 1100
IVTAIQRDSN LPSDLTQACD PEPSPIADTG LTKKRGRKKG TKNKPKLSSG
1110 1120 1130 1140 1150
VDLESSGEFA SIEKMLATTD TNKFSPFLQS TDNFKEESGQ NGTSEDEKET
1160 1170 1180 1190 1200
PEDKLLRGKR NTYSDCPQKI TCPYCPRVFS WASSLQRHML THTDSQADTE
1210 1220 1230 1240 1250
APATGGEVLD LTSCEKEQPE EVSELPGSEC SPQEEQKADS PPAEEDAEEK
1260 1270 1280 1290 1300
ADEYEEGPEE DSVSNKSLDL NFASKLMDFK LAESDQSAGS SSQTERKHAC
1310 1320 1330 1340 1350
DVCGKTFKFA GALSRHKKAH IREDRKDERS SEDESKSIQD DAGAPSMQDS
1360 1370 1380 1390 1400
GLEQEESPMD LKVVESPLDC EATGKENEES ESISEGEGTE RKSTEKSSDD
1410 1420 1430 1440 1450
KIPKTDEAKS TAKADKRKKV CTVCNKRFWS LQDLTRHMRS HTGERPYKCQ
1460 1470 1480 1490 1500
TCERTFTLKH SLVRHQRIHQ KVKNTRNHGK ESDKEETQSR CGEDSENESS
1510 1520 1530 1540 1550
HSGTNPISEN ECDFAGVVGS HPSGTRSRKE SLVGAAKDVP CEEERPSGQG
1560 1570 1580 1590 1600
ATADLVEPAK STQKQPAKDQ EPRGSSELER PSGFIQDLLE MHNKKSPMNH
1610
ILASADSTPQ LLGVE
Length:1,615
Mass (Da):178,389
Last modified:July 10, 2007 - v2
Checksum:i4D22E8480E55874B
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti837L → S in strain: Leghorn. 1 Publication1
Natural varianti932W → C in strain: Leghorn. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF013754 mRNA Translation: AAB96584.1
AF221559 mRNA Translation: AAF71241.1
AF221560 mRNA Translation: AAF71242.1
PIRiJC6510
RefSeqiNP_990380.1, NM_205049.1
UniGeneiGga.1491

Genome annotation databases

GeneIDi395920
KEGGigga:395920

Similar proteinsi

Entry informationi

Entry nameiRREB1_CHICK
AccessioniPrimary (citable) accession number: O57415
Secondary accession number(s): Q9I861
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: March 28, 2018
This is version 109 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health