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Protein
Submitted name:

Melanocortin 2 receptor (Adrenocorticotropic hormone)

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Melanocortin 2 receptor (Adrenocorticotropic hormone)Imported
Submitted name:
Melanocortin 2-receptorImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei45 – 6521HelicalSequence analysisAdd
BLAST
Transmembranei72 – 9120HelicalSequence analysisAdd
BLAST
Transmembranei125 – 15127HelicalSequence analysisAdd
BLAST
Transmembranei163 – 18422HelicalSequence analysisAdd
BLAST
Transmembranei190 – 21526HelicalSequence analysisAdd
BLAST
Transmembranei236 – 25823HelicalSequence analysisAdd
BLAST
Transmembranei278 – 29922HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000022481.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 297242G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000246927.
HOVERGENiHBG108148.
KOiK04200.
PhylomeDBiO57317.

Family and domain databases

InterProiIPR001168. ACTH_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001671. Melcrt_ACTH_rcpt.
[Graphical view]
PANTHERiPTHR22750:SF3. PTHR22750:SF3. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00520. ACTROPHINR.
PR00237. GPCRRHODOPSN.
PR00534. MCRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O57317-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTEKPFNLI LSAHAGQTSI PSLENITDFS LNITDCNQVV VPEEVFFTVA
60 70 80 90 100
AAGILENLLV LVAVIRNKNL HLPMYFFICS LAISDMLGSL YKTLENIFII
110 120 130 140 150
LCKMGYLTRR GDFEKKLDDA MDSMFILSLL GSIFSLLAIA ADRYITIFYA
160 170 180 190 200
LRYHNIMTLQ RALVILAIIW TFCAGSSIAI ALFSHEVATV IPFTILFPLM
210 220 230 240 250
MIFILCLYIH MFLLARSHAK KIASLPTSAV HQRTNMKGAI TLTIFLGVFL
260 270 280 290 300
CCWAPFVLHI LLARFCPHNP YCACYMSIFH VNGTLIMCNA IIDPMIFAFR
310 320 330 340 350
SPELRSTFKK MFCCARYNWN WWKLNEGEYY RSTPMQHHFA ELKILTQNDT

TLAGNCR
Length:357
Mass (Da):40,615
Last modified:June 1, 1998 - v1
Checksum:i055F7242CB7360E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC874995 mRNA. Translation: AGR42637.1.
AB009605 Genomic DNA. Translation: BAA24002.1.
RefSeqiNP_001026686.1. NM_001031515.1.
UniGeneiGga.32095.

Genome annotation databases

GeneIDi428516.
KEGGigga:428516.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC874995 mRNA. Translation: AGR42637.1.
AB009605 Genomic DNA. Translation: BAA24002.1.
RefSeqiNP_001026686.1. NM_001031515.1.
UniGeneiGga.32095.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000022481.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi428516.
KEGGigga:428516.

Organism-specific databases

CTDi4158.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000246927.
HOVERGENiHBG108148.
KOiK04200.
PhylomeDBiO57317.

Family and domain databases

InterProiIPR001168. ACTH_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001671. Melcrt_ACTH_rcpt.
[Graphical view]
PANTHERiPTHR22750:SF3. PTHR22750:SF3. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00520. ACTROPHINR.
PR00237. GPCRRHODOPSN.
PR00534. MCRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning of the chicken melanocortin 2 (ACTH)-receptor gene."
    Takeuchi S., Kudo T., Takahashi S.
    Biochim. Biophys. Acta 1403:102-108(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White LeghoneImported.
  2. Peng K., Ruan L., Liang Y., Liang R.
    Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO57317_CHICK
AccessioniPrimary (citable) accession number: O57317
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.