Rep 68 protein - Adeno-associated virus 2 (AAV-2)

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Unreviewed, UniProtKB/TrEMBL O56650 (O56650_AAV2)

Last modified January 19, 2010. Version 31. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names	Submitted name: Rep 68 protein EMBL AAC03774.1
Organism	Adeno-associated virus 2 (AAV-2) EMBL AAC03774.1
Taxonomic identifier	10804 [NCBI]
Taxonomic lineage	Viruses › ssDNA viruses › Parvoviridae › Parvovirinae › Dependovirus
Virus host	Mammalia [TaxID: 40674]

Protein attributes

Sequence length	536 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)

Sequence similarities

Contains 1 SF3 helicase domain.

Ontologies

Gene Ontology (GO)
Biological process	viral genome replication Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

O56650-1 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: B44187D4E07703C8
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536

60,826

        10         20         30         40         50         60 
MPGFYEIVIK VPSDLDEHLP GISDSFVNWV AEKEWELPPD SDMDLNLIEQ APLTVAEKLQ 

        70         80         90        100        110        120 
RDFLTEWRRV SKAPEALFFV QFEKGESYFH MHVLVETTGV KSMVLGRFLS QIREKLIQRI 

       130        140        150        160        170        180 
YRGIEPTLPN WFAVTKTRNG AGGGNKVVDE CYIPNYLLPK TQPELQWAWT NMEQYLSACL 

       190        200        210        220        230        240 
NLTERKRLVA QHLTHVSQTQ EQNKENQNPN SDAPVIRSKT SARYMELVGW LVDKGITSEK 

       250        260        270        280        290        300 
QWIQEDQASY ISFNAASNSR SQIKAALDNA GKIMSLTKTA PDYLVGQQPV EDISSNRIYK 

       310        320        330        340        350        360 
ILELNGYDPQ YAASVFLGWA TKKFGKRNTI WLFGPATTGK TNIAEAIAHT VPFYGCVNWT 

       370        380        390        400        410        420 
NENFPFNDCV DKMVIWWEEG KMTAKVVESA KAILGGSKVR VDQKCKSSAQ IDPTPVIVTS 

       430        440        450        460        470        480 
NTNMCAVIDG NSTTFEHQQP LQDRMFKFEL TRRLDHDFGK VTKQEVKDFF RWAKDHVVEV 

       490        500        510        520        530 
EHEFYVKKGG AKKRPAPSDA DISEPKRVRE SVAQPSTSDA EASINYADRL ARGHSL

References

[1]	"Mutations in the carboxy terminus of adeno-associated virus 2 capsid proteins affect viral infectivity: lack of an RGD integrin-binding motif." Ruffing M., Heid H., Kleinschmidt J.A. J. Gen. Virol. 75:0-0(0) [PubMed: 7996133] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Berns K.I., Bohenzky R.A., Cassinotti P., Colvin D., Donahue B.A., Dull T., Horer M., Kleinschmidt J.A., Ruffing M., Snyder R.O., Tratschin J.-D., Weitz M. Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF043303 Genomic DNA. Translation: AAC03774.1.
RefSeq	YP_680422.1.
3D structure databases
HSSP	HSSP built from PDB template 1M55 based on UniProtKB Q9YJC1.
ModBase	Search...
Genome annotation databases
GeneID	4192013.
Family and domain databases
InterPro	IPR014015. Helicase_SF3_DNA-vir. IPR001257. Parvovirus_NS1. IPR014835. Rep_N. [Graphical view]
Pfam	PF01057. Parvo_NS1. 1 hit. PF08724. Rep_N. 1 hit. [Graphical view]
PROSITE	PS51206. SF3_HELICASE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O56650_AAV2

Accession

Primary (citable) accession number: O56650

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	January 19, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information