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Protein

Genome polyprotein

Gene
N/A
Organism
Peanut mottle virus (strain M)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Protein inferred from homologyi

Functioni

Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
Nuclear inclusion protein B: an RNA-dependent RNA polymerase that plays an essential role in the virus replication.
Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity).By similarity
Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication.
Both 6K peptides are indispensable for virus replication.By similarity
Nuclear inclusion protein A: has RNA-binding and proteolytic activities.

Catalytic activityi

Hydrolyzes glutaminyl bonds, and activity is further restricted by preferences for the amino acids in P6 - P1' that vary with the species of potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-|-(Ser or Gly) for the enzyme from tobacco etch virus. The natural substrate is the viral polyprotein, but other proteins and oligopeptides containing the appropriate consensus sequence are also cleaved.
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation
Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in the sequence -Tyr-Xaa-Val-Gly-|-Gly, in the processing of the potyviral polyprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei665 – 6651For helper component proteinase activityPROSITE-ProRule annotation
Active sitei738 – 7381For helper component proteinase activityPROSITE-ProRule annotation
Active sitei2103 – 21031For nuclear inclusion protein A activityPROSITE-ProRule annotation
Active sitei2138 – 21381For nuclear inclusion protein A activityPROSITE-ProRule annotation
Active sitei2208 – 22081For nuclear inclusion protein A activityPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi1265 – 12728ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Suppressor of RNA silencing, Thiol protease, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

MEROPSiC06.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyprotein
Cleaved into the following 10 chains:
Alternative name(s):
N-terminal protein
Helper component proteinase (EC:3.4.22.45)
Short name:
HC-pro
6 kDa protein 1
Short name:
6K1
6 kDa protein 2
Short name:
6K2
Alternative name(s):
VPg
Nuclear inclusion protein A (EC:3.4.22.44)
Short name:
NI-a
Short name:
NIa
Alternative name(s):
49 kDa proteinase
Short name:
49 kDa-Pro
NIa-pro
Nuclear inclusion protein B (EC:2.7.7.48)
Short name:
NI-b
Short name:
NIb
Alternative name(s):
RNA-directed RNA polymerase
Capsid protein
Short name:
CP
Alternative name(s):
Coat protein
OrganismiPeanut mottle virus (strain M)
Taxonomic identifieri103926 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stagePotyviridaePotyvirus
Virus hostiArachis hypogaea (Peanut) [TaxID: 3818]
Arachis pintoi [TaxID: 108216]
Cassia [TaxID: 53851]
Glycine max (Soybean) (Glycine hispida) [TaxID: 3847]
Phaseolus vulgaris (Kidney bean) (French bean) [TaxID: 3885]
Pisum sativum (Garden pea) [TaxID: 3888]
Stylosanthes [TaxID: 35627]
Proteomesi
  • UP000000471 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 30993099Genome polyproteinPRO_0000420004Add
BLAST
Chaini1 – 322322P1 proteinaseSequence analysisPRO_0000040305Add
BLAST
Chaini323 – 779457Helper component proteinaseSequence analysisPRO_0000040306Add
BLAST
Chaini780 – 1128349Protein P3By similarityPRO_0000040307Add
BLAST
Chaini1129 – 1180526 kDa protein 1By similarityPRO_0000040308Add
BLAST
Chaini1181 – 1814634Cytoplasmic inclusion proteinBy similarityPRO_0000040309Add
BLAST
Chaini1815 – 1867536 kDa protein 2By similarityPRO_0000040310Add
BLAST
Chaini1868 – 2057190Viral genome-linked proteinBy similarityPRO_0000040311Add
BLAST
Chaini2058 – 2303246Nuclear inclusion protein ABy similarityPRO_0000040312Add
BLAST
Chaini2304 – 2821518Nuclear inclusion protein BBy similarityPRO_0000040313Add
BLAST
Chaini2822 – 3099278Capsid proteinBy similarityPRO_0000040314Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1930 – 19301O-(5'-phospho-RNA)-tyrosineBy similarity

Post-translational modificationi

VPg is uridylylated by the polymerase and is covalently attached to the 5'-end of the genomic RNA. This uridylylated form acts as a nucleotide-peptide primer for the polymerase (By similarity).By similarity
Potyviral RNA is expressed as two polyproteins which undergo post-translational proteolytic processing. Genome polyprotein is processed by NIa-pro, P1 and HC-pro proteinases resulting in the production of at least ten individual proteins. P3N-PIPO polyprotein is cleaved by P1 and HC-pro proteinases resulting in the production of three individual proteins. The P1 proteinase and the HC-pro cleave only their respective C-termini autocatalytically. 6K1 is essential for proper proteolytic separation of P3 from CI (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei322 – 3232Cleavage; by P1 proteinaseSequence analysis
Sitei779 – 7802Cleavage; by autolysisPROSITE-ProRule annotation
Sitei1128 – 11292Cleavage; by NIa-proBy similarity
Sitei1180 – 11812Cleavage; by NIa-proBy similarity
Sitei1814 – 18152Cleavage; by NIa-proBy similarity
Sitei1867 – 18682Cleavage; by NIa-proBy similarity
Sitei2057 – 20582Cleavage; by NIa-proBy similarity
Sitei2303 – 23042Cleavage; by NIa-proBy similarity
Sitei2821 – 28222Cleavage; by NIa-proBy similarity

Keywords - PTMi

Covalent protein-RNA linkage, Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliO56075.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini657 – 779123Peptidase C6PROSITE-ProRule annotationAdd
BLAST
Domaini1252 – 1404153Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1423 – 1582160Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST
Domaini2058 – 2276219Peptidase C4PROSITE-ProRule annotationAdd
BLAST
Domaini2545 – 2669125RdRp catalyticPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi374 – 3774Involved in interaction with stylet and aphid transmissionBy similarity
Motifi631 – 6333Involved in virions binding and aphid transmissionBy similarity
Motifi1354 – 13574DESH box
Motifi1906 – 191510Nuclear localization signalSequence analysis

Domaini

The N-terminus of helper component proteinase is involved in interaction with stylets. The central part is involved in interaction with virions and the C-terminus is involved in cell-to cell movement of the virus.

Sequence similaritiesi

Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation
Contains 1 peptidase C4 domain.PROSITE-ProRule annotation
Contains 1 peptidase C6 domain.PROSITE-ProRule annotationCurated
Contains 1 peptidase S30 domain.Curated
Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform Genome polyprotein (identifier: O56075-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASITFGNAC TVVFGQVRKE EVTAGPVAVN LNEGTRMVVV PTAAQMATPT
60 70 80 90 100
PSVSIKIINR WSNKAVSSYE RQVEDVFANF FAKKERSDEL LTRYYGKVVQ
110 120 130 140 150
KGNKLMVKRA PLHVARVLEK QRLQDIEDEK AFLQYRDAGV HVAGSVKFTD
160 170 180 190 200
TRSRGQTVSF RTEHYKPTGK IVQKKKAQKQ RANADVDHLI DEVMKICSAD
210 220 230 240 250
CKQVEFISMG KRRLTAKFKL FGKSVIPCIH LAHEQGRRLR RELDPRIHEQ
260 270 280 290 300
VIAHLVTGRK VRELIKDDMV TYGWSGAILN KNLFKRTPFR WDEVVIRGRL
310 320 330 340 350
YGKLVDARSK LSECSKDKIH QYSSFEAQFW KGWKNKFDTL HPHNKDHICE
360 370 380 390 400
PTINNEKCGE IVATIFQAIH PVIKVSCSTC RERLTKASNE ELNEYLATNL
410 420 430 440 450
ACHKATFDDM RQQHATVNTV LNKIEQTSLA NPNLKDSMEI VRLLQNLNQT
460 470 480 490 500
QARQLMKVNN TLLKGNVATS EEFSDATTQL LEVTRWYAKH LSLVDEGSIS
510 520 530 540 550
SFRNKATSKS LINPSLLCDN QLDRNGNFVW GERGRHSKRF FENFFEEVVP
560 570 580 590 600
GGGYKKYQIR NSPNCTRKLA IGNLIVPMSL ERARNALIGE SVERLPVTEA
610 620 630 640 650
CVSRVNGAFM HVASCVTSDN GSAHFSPLYS PTKRHLVVGT TGDSKYIDLP
660 670 680 690 700
ATESDKMYVA KEGYCYINIF LAMLVNVNED SAKDFTKMIR DTIVPMLGTW
710 720 730 740 750
PSMMDVATAC YILTVFHPET KSAELPRILV DHTNKTMHVI DSFGSISTGY
760 770 780 790 800
HILKAGTVSQ LIHFASNELV SEMKHYVVGG EAPHARRMRM EKALIQGIFK
810 820 830 840 850
PKQLVYLIEE DPYILMMSLV SPTLLINLFN VGGLEVAMKH WIKKEMNIGL
860 870 880 890 900
IFSMLSSLAQ KVSRADLVNE QITMIDANAA QFIETLAGID VENPMRNELV
910 920 930 940 950
SALTMMLARS DVDSTLNKTG FTGFSDTLLE MREKIIGDEL NKVWSELSWW
960 970 980 990 1000
EKFSSIIFSR RARKHIMAPL PNTKLHAIDD RYAISCTWLH GKIKARFNGA
1010 1020 1030 1040 1050
KSATLEVCKK VTSILKRNTV DSILYICRKC YSDIFYFVNV MLISSMILSV
1060 1070 1080 1090 1100
IYTMHKMVIE SRAHKQAMVI MKMREDELVV KQMYDQYCKL ANETPTKEEF
1110 1120 1130 1140 1150
FQYVCKMNKE LGERIAPEFE EGSLVVYQAK TETELGLEKV VAYLALIAMI
1160 1170 1180 1190 1200
FDGERSDAVF RALSKLKTVF GTLGETVRYQ SLDEIESVAD EKKMTIDFEL
1210 1220 1230 1240 1250
EGSEASSSTV MSAKFSDWWY KQLETNRVVP HYRIGGEFVE FTRKTAAEVV
1260 1270 1280 1290 1300
NNMRASNASE FLVRGAVGSG KSTGLPHLLA QKGRVLLLEP TRPLAENVCK
1310 1320 1330 1340 1350
QLRQAPFQQN PTLRMRGLTT FGSSNIVIMT SGFALHYYAN NPTKLQEYDF
1360 1370 1380 1390 1400
VMIDESHTMD ASAMAFYCLV REYNFQGKII KVSATPPGKE CEFKTQFDVA
1410 1420 1430 1440 1450
LLIEEDLSFQ QFAQSQGQGG NADMTKHGDN ILVYVASYND VDQLAELLIR
1460 1470 1480 1490 1500
GNHFVTKVDG RTMKMGSTEI VSKGTASKKH YIIATNIIEN GVTLDVDVVV
1510 1520 1530 1540 1550
DFGQKVVAEL DGDSRCMRYR KVAVSYGERI QRLGRVGRVK KGTALRIGHT
1560 1570 1580 1590 1600
EHGISEIPAS ISTEAAFLCF AYGLPVITHN VTVSILANCT VQQARTMMLF
1610 1620 1630 1640 1650
ELSPFFLADL VKYNGSMHPE VHKLLKPYKL RDSEIELCKL AIPNSSIGRW
1660 1670 1680 1690 1700
LSVHEYAKLG IKIHAVDSVR IPFAGRGIPD KLYSELWHII QEHKHEAGFG
1710 1720 1730 1740 1750
RLTSASASTI AYTLSTDPEA IPRTIALLDN LIAEEMQKKA HFEALNSTLC
1760 1770 1780 1790 1800
SQRFTLKNIV DTVRQRYMKD HSKHNIEVLQ SARSQILEFN SATHDFKKVA
1810 1820 1830 1840 1850
SLLGYGFLDT VQYQSKNELS KRLGLKGRWN KSLVTNDLLV CGMVLFGGVW
1860 1870 1880 1890 1900
MVWEYAKSAM NEPVRYQGKR QNQKLKFRDA RDRKVGREVY GDDGTIEHFF
1910 1920 1930 1940 1950
GEAYTKKGKS KGNHTVKGMG RKTRRFIHMY GFDPTEYSFV RFVDPLTGYA
1960 1970 1980 1990 2000
IDENITCDIS LVQDEVAEVR KQFINEDEIS AQSIAENPGI IAYYMSRNAD
2010 2020 2030 2040 2050
KALKIDLTPH NPLAVGRGGS SIAGFPEREY ELRQTGKPLE VKKSEVPPVS
2060 2070 2080 2090 2100
KDVVATEGKS MCRGLRNYNP IATSICKLVN ESDGHSETIH GIGFGPVIIT
2110 2120 2130 2140 2150
NSHLFRRNNG TLQIQTHHGV FRVKNSTQLQ VSHMAKKDMI IIKMPCDVPP
2160 2170 2180 2190 2200
FPSKLRFRQP EQGEKAVLVG SLFQQKSITS SVSESTMVMP VNDSGYWRHW
2210 2220 2230 2240 2250
VSTKDGDCGL PLVSTVDGAI LGLHGLTSTK SDRNYFVPFD EQFERDILAN
2260 2270 2280 2290 2300
LEKLDWKRHW LHSSDLIAWG GMSLKENHPH DCFRTSKLVT DLLGLTKDSV
2310 2320 2330 2340 2350
EYQSGQDKWV LAGLENNLKA VAQSESQLVT KHVVKGQCMY FQEYLATHST
2360 2370 2380 2390 2400
AEKFFKPLMG AYQPSKLNKE AFTKDLYKYQ NEIIVGEVDK DAFDNAVEAV
2410 2420 2430 2440 2450
IYLLDDLGFG ECAYVTDEEA ILDSLNMKAA VGALYKGKKK EYFESLSEPE
2460 2470 2480 2490 2500
KHHIVQASCE RLFYGEMGVW NGSLKAELRP KEKVALNKTR TFTAAPIDTL
2510 2520 2530 2540 2550
LGGKCCVDDF NNRFYSLNIE GPWTVGMTKF YGGWDKLMRK LPDGWRYCHA
2560 2570 2580 2590 2600
DGSQFDSSLT PFLLNAVLAV RLMFMEDWWV GEQMLRNFYT EIIYTPILTP
2610 2620 2630 2640 2650
DGTIVKKFKG NNSGQPSTVV DNTLMVMIAM FYGMKKLNWT DEQIKERIVF
2660 2670 2680 2690 2700
FAXGDDLIIA VQPEHEGILD TLQRSLGELG LKYDFSERCD DRQELWFMSH
2710 2720 2730 2740 2750
QGHLVDGMYI PKLEQERIVS ILEWDRSTVI EHRAEAICAA MIEAWGYPEL
2760 2770 2780 2790 2800
LKQIRLFYAW ILDHDMFKSL VAEGKLPYIA ETALRKLYTD ADATDVELEE
2810 2820 2830 2840 2850
YILRFTEVDE DEDHNDEVRY QSGENKSKVE VDAAAAKLKE KEKEKHKKTE
2860 2870 2880 2890 2900
EGTSEGTSQT KEPDVDTGSQ GIVYVPKLAK ITKKMRMPMV GGQVILHIPH
2910 2920 2930 2940 2950
LLDYKPEQVD LSNTRSSQQQ FTAWYNGLKE AYEITDDTSM SVLMNGLMVW
2960 2970 2980 2990 3000
CIENGTSPNI NGNWTMMDGH EQNEYPLKPV IENAKPTFRQ IMHHFSDAAE
3010 3020 3030 3040 3050
AYIEMRNAEK PYMPRYGLQR NLRDFSYARI AFDFYEITSR TSAKAREIHM
3060 3070 3080 3090
QMKAAALNNV AIKTFGLDGN VGTQDEDTER HTANDVNRNM HSLLGMRQM
Note: Produced by conventional translation.
Length:3,099
Mass (Da):351,038
Last modified:June 1, 1998 - v1
Checksum:i0D8E9FC7603F0A4B
GO
Isoform P3N-PIPO polyprotein (identifier: P0CK00-1) [UniParc]FASTAAdd to basket

The sequence of this isoform can be found in the external entry P0CK00.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by -1 ribosomal frameshifting in P3 ORF.
Length:1,008
Mass (Da):114,275
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF023848 Genomic RNA. Translation: AAB94595.1.
RefSeqiNP_068348.2. NC_002600.1.

Genome annotation databases

GeneIDi912241.
KEGGivg:912241.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF023848 Genomic RNA. Translation: AAB94595.1.
RefSeqiNP_068348.2. NC_002600.1.

3D structure databases

ProteinModelPortaliO56075.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiC06.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi912241.
KEGGivg:912241.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete nucleotide sequence of peanut mottle virus (M strain) genomic RNA."
    Flasinski S., Gonzales R.A., Cassidy B.G.
    Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. Cited for: REVIEW.

Entry informationi

Entry nameiPOLG_PEMVM
AccessioniPrimary (citable) accession number: O56075
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: June 1, 1998
Last modified: December 9, 2015
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.