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Protein

Protein C

Gene

P/V/C

Organism
Hendra virus (isolate Horse/Autralia/Hendra/1994)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May counteract the cellular interferon antiviral system.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Interferon antiviral system evasion

Names & Taxonomyi

Protein namesi
Recommended name:
Protein C
Gene namesi
Name:P/V/C
OrganismiHendra virus (isolate Horse/Autralia/Hendra/1994)
Taxonomic identifieri928303 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesMononegaviralesParamyxoviridaeParamyxovirinaeHenipavirus
Virus hostiEquus caballus (Horse) [TaxID: 9796]
Homo sapiens (Human) [TaxID: 9606]
Pteropus alecto (Black flying fox) [TaxID: 9402]
Pteropus poliocephalus (Grey-headed flying fox) [TaxID: 9403]
Pteropus scapulatus (Little red flying fox) [TaxID: 94117]
Proteomesi
  • UP000008771 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 166166Protein CPRO_0000236018Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiO55779. 9 interactions.

Family & Domainsi

Family and domain databases

InterProiIPR031812. C_Hendra.
[Graphical view]
PfamiPF16821. C_Hendra. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O55779-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMASILLTLF RRTKKKYKRH TDDQASNNQV PKTGQEHGRT SCRAPVENMN
60 70 80 90 100
RLRGECLRMM EVLKEEMWRI YPVLLPQMEL LDKECQTPEL GQKTQMTYNW
110 120 130 140 150
TQWLQTLYTM IMEENVPDMD LLQALREGGV ITCQEHTMGM YVLYLIQRCC
160
PMLPKLQFLK KLGKLI
Length:166
Mass (Da):19,646
Last modified:June 1, 1998 - v1
Checksum:i0213AAA3B704DD02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010304 mRNA. Translation: AAC04242.1.
AF017149 Genomic RNA. Translation: AAC83190.1.
PIRiT08208.
RefSeqiNP_047109.1. NC_001906.3.

Genome annotation databases

GeneIDi1446469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010304 mRNA. Translation: AAC04242.1.
AF017149 Genomic RNA. Translation: AAC83190.1.
PIRiT08208.
RefSeqiNP_047109.1. NC_001906.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO55779. 9 interactions.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1446469.

Family and domain databases

InterProiIPR031812. C_Hendra.
[Graphical view]
PfamiPF16821. C_Hendra. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A novel P/V/C gene in a new member of the Paramyxoviridae family, which causes lethal infection in humans, horses, and other animals."
    Wang L.-F., Michalski W.P., Yu M., Pritchard L.I., Crameri G., Shiell B., Eaton B.T.
    J. Virol. 72:1482-1490(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The exceptionally large genome of Hendra virus: support for creation of a new genus within the family Paramyxoviridae."
    Wang L.-F., Yu M., Hansson E., Pritchard L.I., Shiell B., Michalski W.P., Eaton B.T.
    J. Virol. 74:9972-9979(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiC_HENDH
AccessioniPrimary (citable) accession number: O55779
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: June 1, 1998
Last modified: November 11, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

The P/V/C gene has two overlapping open reading frames. One encodes the P/V/W proteins and the other the C protein.

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.