O55764 (172L_IIV6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative helicase 172L
EC=3.6.4.-

Gene names

ORF Names:

IIV6-172L

Organism

Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) [Reference proteome]

Taxonomic identifier

176652 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Iridovirus

Virus host

Acheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]

Protein attributes

Sequence length	606 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the SNF2/RAD54 helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro helicase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 606	606	Putative helicase 172L		PRO_0000378036
Regions
	Domain	59 – 264	206	Helicase ATP-binding
	Domain	437 – 586	150	Helicase C-terminal
	Nucleotide binding	72 – 79	8	ATP By similarity
Natural variations
	Natural variant	128 – 129	2	RD → KS.
	Natural variant	446	1	S → M.

Sequences

	Sequence		Length	Mass (Da)
	O55764 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: CE96322F3801A6F5	FASTA	606	69,658
	10 20 30 40 50 60 MADAMNELCN LTQHLQVDDD QLSNLKLKNG YSLFPHQEKV MLWMKYRENL TKKECRKEGE 70 80 90 100 110 120 KTWGVRGGII SLCMGLGKTL TALAYSFQNK ASFPTLVITS KTVMHEWKTE GVEKFFDSDN 130 140 150 160 170 180 IRVLYLHRDY IKNIDKISRD DIMTYDIVIT TYDVCLFACK KGNYFLQCFE MGEEQSLMKN 190 200 210 220 230 240 KIVAIHTRKR KDANLPNLKG TAVIYGTPWE RVICDESQKF ANPKTMTYKC IMAVYGKYKW 250 260 270 280 290 300 CLTGTPIRNY ETDIWAQLRF CGYKGVERSH DWNRNGQGLI AFKDHNLISA IFTMSYDDAQ 310 320 330 340 350 360 MSLPEKTENN LTVKLEGQHK EIYEGILTET REMYKKMMND LCSFTYVLAM FTRLRQCAIA 370 380 390 400 410 420 PYLITPDAKR NSKEKKNCSE WCLDKFGGAG IKSSKILKIV EIIKSVTLND NPNCNSNPKS 430 440 450 460 470 480 LQLLAKEKAY SCFGSDYIKS SNFEISHPTK IIVFSMFTSC LDLLSEAIKE DYPNFKFVQV 490 500 510 520 530 540 DGDTKNRSEL FDQFKNDINT QGLFLTYKVG SEGLNLTEAT HCICIEPWWT NAVHNQAKAR 550 560 570 580 590 600 LWRTGQTKQV YVHNVIIEGS IEEKIVEICK GKDDMAASYL EGKERIKSPV RAPKLDKFTL GKMLGI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus." Jakob N.J., Mueller K., Bahr U., Darai G. Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Identification of the primary structure and the coding capacity of the genome of insect iridescent virus type 6 between the genome coordinates 0.310 and 0.347 (7990 bp)." Sonntag K.-C., Schnitzler P., Janssen W., Darai G. Intervirology 37:287-297(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes." Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R. Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF303741 Genomic DNA. Translation: AAA62412.2. S75674 Genomic DNA. Translation: AAB33905.1.
PIR	T03177.
RefSeq	NP_149635.1. NC_003038.1.
3D structure databases
ProteinModelPortal	O55764.
ModBase	Search...
Proteomic databases
PRIDE	O55764.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1732980.
Family and domain databases
InterPro	IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR000330. SNF2_N. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. PF00176. SNF2_N. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

172L_IIV6

Accession

Primary (citable) accession number: O55764
Secondary accession number(s): Q89442

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2009
Last sequence update:	June 1, 1998
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program