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O55761

- 165R_IIV6

UniProt

O55761 - 165R_IIV6

Protein

Putative metalloproteinase 165R

Gene

IIV6-165R

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Jun 1998)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 zinc ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi93 – 931Zinc; catalyticPROSITE-ProRule annotation
    Active sitei94 – 941PROSITE-ProRule annotation
    Metal bindingi97 – 971Zinc; catalyticPROSITE-ProRule annotation
    Metal bindingi103 – 1031Zinc; catalyticPROSITE-ProRule annotation

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro
    2. zinc ion binding Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Metalloprotease, Protease

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative metalloproteinase 165R (EC:3.4.24.-)
    Gene namesi
    ORF Names:IIV6-165R
    OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
    Taxonomic identifieri176652 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
    Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
    Chilo suppressalis (striped riceborer) [TaxID: 168631]
    Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
    Gryllus campestris [TaxID: 58607]
    Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
    ProteomesiUP000001359: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular matrix Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 264264Putative metalloproteinase 165RPRO_0000377912Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO55761.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi145 – 23490Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the peptidase M10A family.Curated

    Family and domain databases

    Gene3Di3.40.390.10. 1 hit.
    InterProiIPR024079. MetalloPept_cat_dom.
    IPR001818. Pept_M10_metallopeptidase.
    IPR021190. Pept_M10A.
    IPR006026. Peptidase_Metallo.
    [Graphical view]
    PfamiPF00413. Peptidase_M10. 1 hit.
    [Graphical view]
    PRINTSiPR00138. MATRIXIN.
    SMARTiSM00235. ZnMc. 1 hit.
    [Graphical view]
    PROSITEiPS00142. ZINC_PROTEASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O55761-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKINTTDVRT AIYHSLQQWQ SVSLLTFKEE YYDENADIKV SFVKGKHNDG    50
    WDFDGKGRIL AHAFFPSGSM RGVVHLDYDE DWDFASLKQV LLHELGHTFG 100
    LGHSSDNKSI MFPWNSSSVD NVNQDDKNGI EWLYGLKNKW AKLSPPVTKP 150
    PVTKPPVTKP ILTTVPRFPV PTTQVPIIQP RFGNPTTHSP TTRHPLQKIP 200
    IQPRFGHSNP PIRYNPPIRY NPKHPLSPPF KSIPNSLLNV VNSSITNLYV 250
    YFPNTWNSSI IKFN 264
    Length:264
    Mass (Da):30,080
    Last modified:June 1, 1998 - v1
    Checksum:i8886A8896F8D3AFE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAB94472.1.
    PIRiT03174.
    RefSeqiNP_149628.1. NC_003038.1.

    Genome annotation databases

    GeneIDi1733354.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAB94472.1 .
    PIRi T03174.
    RefSeqi NP_149628.1. NC_003038.1.

    3D structure databases

    ProteinModelPortali O55761.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1733354.

    Family and domain databases

    Gene3Di 3.40.390.10. 1 hit.
    InterProi IPR024079. MetalloPept_cat_dom.
    IPR001818. Pept_M10_metallopeptidase.
    IPR021190. Pept_M10A.
    IPR006026. Peptidase_Metallo.
    [Graphical view ]
    Pfami PF00413. Peptidase_M10. 1 hit.
    [Graphical view ]
    PRINTSi PR00138. MATRIXIN.
    SMARTi SM00235. ZnMc. 1 hit.
    [Graphical view ]
    PROSITEi PS00142. ZINC_PROTEASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
      Jakob N.J., Mueller K., Bahr U., Darai G.
      Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
      Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
      Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.

    Entry informationi

    Entry namei165R_IIV6
    AccessioniPrimary (citable) accession number: O55761
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3