O55761 (165R_IIV6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative metalloproteinase 165R
EC=3.4.24.-

Gene names

ORF Names:

IIV6-165R

Organism

Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) [Reference proteome]

Taxonomic identifier

176652 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Iridovirus

Virus host

Acheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 zinc ion per subunit By similarity.
Sequence similarities	Belongs to the peptidase M10A family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Hydrolase Metalloprotease Protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular_function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	Putative metalloproteinase 165R		PRO_0000377912
Regions
	Compositional bias	145 – 234	90	Pro-rich
Sites
	Active site	94	1	By similarity
	Metal binding	93	1	Zinc; catalytic By similarity
	Metal binding	97	1	Zinc; catalytic By similarity
	Metal binding	103	1	Zinc; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	O55761 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 8886A8896F8D3AFE	FASTA	264	30,080
	10 20 30 40 50 60 MKINTTDVRT AIYHSLQQWQ SVSLLTFKEE YYDENADIKV SFVKGKHNDG WDFDGKGRIL 70 80 90 100 110 120 AHAFFPSGSM RGVVHLDYDE DWDFASLKQV LLHELGHTFG LGHSSDNKSI MFPWNSSSVD 130 140 150 160 170 180 NVNQDDKNGI EWLYGLKNKW AKLSPPVTKP PVTKPPVTKP ILTTVPRFPV PTTQVPIIQP 190 200 210 220 230 240 RFGNPTTHSP TTRHPLQKIP IQPRFGHSNP PIRYNPPIRY NPKHPLSPPF KSIPNSLLNV 250 260 VNSSITNLYV YFPNTWNSSI IKFN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus." Jakob N.J., Mueller K., Bahr U., Darai G. Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes." Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R. Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF303741 Genomic DNA. Translation: AAB94472.1.
PIR	T03174.
RefSeq	NP_149628.1. NC_003038.1.
3D structure databases
HSSP	HSSP built from PDB template 1CGL based on UniProtKB P03956.
ProteinModelPortal	O55761.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1733354.
Family and domain databases
Gene3D	3.40.390.10. 1 hit.
InterPro	IPR024079. MetalloPept_cat_dom. IPR001818. Pept_M10_metallopeptidase. IPR021190. Pept_M10A. IPR006026. Peptidase_Metallo. [Graphical view]
Pfam	PF00413. Peptidase_M10. 1 hit. [Graphical view]
PRINTS	PR00138. MATRIXIN.
SMART	SM00235. ZnMc. 1 hit. [Graphical view]
PROSITE	PS00142. ZINC_PROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

165R_IIV6

Accession

Primary (citable) accession number: O55761

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2009
Last sequence update:	June 1, 1998
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program