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Protein

Putative ribonuclease 3

Gene

IIV6-142R

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Digests double-stranded RNA.By similarity

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.

GO - Molecular functioni

  1. ribonuclease III activity Source: UniProtKB-EC
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ribonuclease 3 (EC:3.1.26.3)
Alternative name(s):
Ribonuclease III
Short name:
RNase III
Gene namesi
ORF Names:IIV6-142R
OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Taxonomic identifieri176652 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
ProteomesiUP000001359: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 292292Putative ribonuclease 3PRO_0000376954Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO55748.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 158127RNase IIIPROSITE-ProRule annotationAdd
BLAST
Domaini204 – 27673DRBMPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the IIV-6 142R family.Curated
Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation
Contains 1 RNase III domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.1520.10. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000999. RNase_III_dom.
[Graphical view]
PfamiPF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTiSM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMiSSF69065. SSF69065. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O55748-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENNIENFDP SLVYFGDRGQ DFKKMIRSIL SLGMSDEYIP YLTTPESLNT
60 70 80 90 100
YNTAFTSRGA DDKNNYEMFE QLGDVSVNKF IVNYMYKRFP QLRNPNGVDV
110 120 130 140 150
VAKLKIKYAS KNQLQMLSES LDMWRFITAT YDERTNKKKP LLEDTFESFF
160 170 180 190 200
GATEWLIDSF IEDIALKQGN NNTYVGVGYN IINGILTTLF DRINISLKYE
210 220 230 240 250
NLVDAKTRFN EVIAEQKSII GDVKYEDEYK NGKHTSKIYR YPPNSNLKEL
260 270 280 290
LGIGTGTLKR DAQEQAASRA LETLALKHNI IKEAPDRFKA FM
Length:292
Mass (Da):33,664
Last modified:June 1, 1998 - v1
Checksum:iAEFBC85399291FC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAB94459.1.
PIRiT03085.
RefSeqiNP_149605.1. NC_003038.1.

Genome annotation databases

GeneIDi1733045.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAB94459.1.
PIRiT03085.
RefSeqiNP_149605.1. NC_003038.1.

3D structure databases

ProteinModelPortaliO55748.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1733045.

Family and domain databases

Gene3Di1.10.1520.10. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000999. RNase_III_dom.
[Graphical view]
PfamiPF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTiSM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMiSSF69065. SSF69065. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
    Jakob N.J., Mueller K., Bahr U., Darai G.
    Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
    Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
    Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.

Entry informationi

Entry nameiRNC_IIV6
AccessioniPrimary (citable) accession number: O55748
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: June 1, 1998
Last modified: January 7, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.