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O55748 (RNC_IIV6) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
ORF Names:IIV6-142R
OrganismInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus) [Reference proteome]
Taxonomic identifier176652 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA By similarity.

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester.

Sequence similarities

Belongs to the IIV-6 142R family.

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processRNA processing

Inferred from electronic annotation. Source: InterPro

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

ribonuclease III activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Putative ribonuclease 3
PRO_0000376954

Regions

Domain32 – 158127RNase III
Domain204 – 27673DRBM

Sequences

Sequence LengthMass (Da)Tools
O55748 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: AEFBC85399291FC3

FASTA29233,664
        10         20         30         40         50         60 
MENNIENFDP SLVYFGDRGQ DFKKMIRSIL SLGMSDEYIP YLTTPESLNT YNTAFTSRGA 

        70         80         90        100        110        120 
DDKNNYEMFE QLGDVSVNKF IVNYMYKRFP QLRNPNGVDV VAKLKIKYAS KNQLQMLSES 

       130        140        150        160        170        180 
LDMWRFITAT YDERTNKKKP LLEDTFESFF GATEWLIDSF IEDIALKQGN NNTYVGVGYN 

       190        200        210        220        230        240 
IINGILTTLF DRINISLKYE NLVDAKTRFN EVIAEQKSII GDVKYEDEYK NGKHTSKIYR 

       250        260        270        280        290 
YPPNSNLKEL LGIGTGTLKR DAQEQAASRA LETLALKHNI IKEAPDRFKA FM 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
Jakob N.J., Mueller K., Bahr U., Darai G.
Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF303741 Genomic DNA. Translation: AAB94459.1.
PIRT03085.
RefSeqNP_149605.1. NC_003038.1.

3D structure databases

ProteinModelPortalO55748.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1733045.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
InterProIPR014720. dsRNA-bd_dom.
IPR000999. RNase_III_dom.
[Graphical view]
PfamPF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_IIV6
AccessionPrimary (citable) accession number: O55748
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: June 1, 1998
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families