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O55748

- RNC_IIV6

UniProt

O55748 - RNC_IIV6

Protein

Putative ribonuclease 3

Gene

IIV6-142R

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Jun 1998)
      Previous versions | rss
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    Functioni

    Digests double-stranded RNA.By similarity

    Catalytic activityi

    Endonucleolytic cleavage to 5'-phosphomonoester.

    GO - Molecular functioni

    1. ribonuclease III activity Source: UniProtKB-EC
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative ribonuclease 3 (EC:3.1.26.3)
    Alternative name(s):
    Ribonuclease III
    Short name:
    RNase III
    Gene namesi
    ORF Names:IIV6-142R
    OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
    Taxonomic identifieri176652 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
    Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
    Chilo suppressalis (striped riceborer) [TaxID: 168631]
    Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
    Gryllus campestris [TaxID: 58607]
    Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
    ProteomesiUP000001359: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 292292Putative ribonuclease 3PRO_0000376954Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO55748.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini32 – 158127RNase IIIPROSITE-ProRule annotationAdd
    BLAST
    Domaini204 – 27673DRBMPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the IIV-6 142R family.Curated
    Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation
    Contains 1 RNase III domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di1.10.1520.10. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR000999. RNase_III_dom.
    [Graphical view]
    PfamiPF00636. Ribonuclease_3. 1 hit.
    [Graphical view]
    SMARTiSM00535. RIBOc. 1 hit.
    [Graphical view]
    SUPFAMiSSF69065. SSF69065. 1 hit.
    PROSITEiPS50137. DS_RBD. 1 hit.
    PS50142. RNASE_3_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O55748-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENNIENFDP SLVYFGDRGQ DFKKMIRSIL SLGMSDEYIP YLTTPESLNT    50
    YNTAFTSRGA DDKNNYEMFE QLGDVSVNKF IVNYMYKRFP QLRNPNGVDV 100
    VAKLKIKYAS KNQLQMLSES LDMWRFITAT YDERTNKKKP LLEDTFESFF 150
    GATEWLIDSF IEDIALKQGN NNTYVGVGYN IINGILTTLF DRINISLKYE 200
    NLVDAKTRFN EVIAEQKSII GDVKYEDEYK NGKHTSKIYR YPPNSNLKEL 250
    LGIGTGTLKR DAQEQAASRA LETLALKHNI IKEAPDRFKA FM 292
    Length:292
    Mass (Da):33,664
    Last modified:June 1, 1998 - v1
    Checksum:iAEFBC85399291FC3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAB94459.1.
    PIRiT03085.
    RefSeqiNP_149605.1. NC_003038.1.

    Genome annotation databases

    GeneIDi1733045.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAB94459.1 .
    PIRi T03085.
    RefSeqi NP_149605.1. NC_003038.1.

    3D structure databases

    ProteinModelPortali O55748.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1733045.

    Family and domain databases

    Gene3Di 1.10.1520.10. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR000999. RNase_III_dom.
    [Graphical view ]
    Pfami PF00636. Ribonuclease_3. 1 hit.
    [Graphical view ]
    SMARTi SM00535. RIBOc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69065. SSF69065. 1 hit.
    PROSITEi PS50137. DS_RBD. 1 hit.
    PS50142. RNASE_3_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
      Jakob N.J., Mueller K., Bahr U., Darai G.
      Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
      Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
      Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.

    Entry informationi

    Entry nameiRNC_IIV6
    AccessioniPrimary (citable) accession number: O55748
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3