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O55259

- O55259_HHV1

UniProt

O55259 - O55259_HHV1

Protein
Submitted name:

Thymidine kinase

Gene

UL23

Organism
Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 2 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. thymidine kinase activity Source: InterPro

    GO - Biological processi

    1. TMP biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Thymidine kinaseImported
    Gene namesi
    Name:UL23Imported
    OrganismiHuman herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)Imported
    Taxonomic identifieri10298 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]

    Structurei

    3D structure databases

    ProteinModelPortaliO55259.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR001889. Herpes_TK.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00693. Herpes_TK. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O55259-1 [UniParc]FASTAAdd to Basket

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    MASYPCHQHA SAFDQAARSR GHSNRRTALR PRRQQEATEV RPEQKMPTLL    50
    RVYIDGPHGM GKTTTTQLLV ALGSRDDIVY VPEPMTYWRV LGASETIANI 100
    YTTQHRLDQG EISAGDAAVV MTSAQITMGM PYAVTDAVLA PHIGGEAGSS 150
    HAPPPALTLI FDRHPIAALL CYPAARYLMG SMTPQAVLAF VALIPPTLPG 200
    TNIVLGALPE DRHIDRLAKR QRPGERLDLA MLAAIRRVYG LLANTVRYLQ 250
    CGGSWREDWG QLSGTALTPQ GAEPQSNAGP RPHIGETLFT LFRAPELLAP 300
    NGDLYNVFAW ALDVLAKRLR PMHVFILDYD QSPAGCRDAL LQLTSGMVQT 350
    HVTTPGSIPT ICDLARTFAR EMGEAH 376
    Length:376
    Mass (Da):41,010
    Last modified:October 1, 2001 - v2
    Checksum:i9CCFAB1D218030BF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JQ895546 Genomic DNA. Translation: AFU56940.1.
    AB009254 Genomic DNA. Translation: BAA23729.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JQ895546 Genomic DNA. Translation: AFU56940.1 .
    AB009254 Genomic DNA. Translation: BAA23729.2 .

    3D structure databases

    ProteinModelPortali O55259.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR001889. Herpes_TK.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00693. Herpes_TK. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the relationship between cellular thymidine kinase activity and virulence of thymidine kinase-negative herpes simplex virus types 1 and 2."
      Suzutani T., Koyano S., Takada M., Yoshida I., Azuma M.
      Microbiol. Immunol. 39:787-794(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: VR-3Imported.
    2. Suzutani T.
      Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: VR-3Imported.
    3. "Longitudinal study on oral shedding of herpes simplex virus 1 and varicella-zoster virus in individuals infected with HIV."
      van Velzen M., Ouwendijk W.J., Selke S., Pas S.D., van Loenen F.B., Osterhaus A.D., Wald A., Verjans G.M.
      J. Med. Virol. 85:1669-1677(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 5Imported.

    Entry informationi

    Entry nameiO55259_HHV1
    AccessioniPrimary (citable) accession number: O55259
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 1998
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 43 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)