O55259 (O55259_HHV1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Thymidine kinase EMBL BAA23729.2

Gene names

Name:

UL23 EMBL BAA23729.2

Organism

Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) EMBL BAA23729.2

Taxonomic identifier

10298 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Alphaherpesvirinae › Simplexvirus

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Kinase EMBL BAA23729.2 Transferase
Gene Ontology (GO)
Biological_process	TMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro thymidine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O55259 [UniParc]. Last modified October 1, 2001. Version 2. Checksum: 9CCFAB1D218030BF	FASTA	376	41,010
	10 20 30 40 50 60 MASYPCHQHA SAFDQAARSR GHSNRRTALR PRRQQEATEV RPEQKMPTLL RVYIDGPHGM 70 80 90 100 110 120 GKTTTTQLLV ALGSRDDIVY VPEPMTYWRV LGASETIANI YTTQHRLDQG EISAGDAAVV 130 140 150 160 170 180 MTSAQITMGM PYAVTDAVLA PHIGGEAGSS HAPPPALTLI FDRHPIAALL CYPAARYLMG 190 200 210 220 230 240 SMTPQAVLAF VALIPPTLPG TNIVLGALPE DRHIDRLAKR QRPGERLDLA MLAAIRRVYG 250 260 270 280 290 300 LLANTVRYLQ CGGSWREDWG QLSGTALTPQ GAEPQSNAGP RPHIGETLFT LFRAPELLAP 310 320 330 340 350 360 NGDLYNVFAW ALDVLAKRLR PMHVFILDYD QSPAGCRDAL LQLTSGMVQT HVTTPGSIPT 370 ICDLARTFAR EMGEAH

References

[1]	"Analysis of the relationship between cellular thymidine kinase activity and virulence of thymidine kinase-negative herpes simplex virus types 1 and 2." Suzutani T., Koyano S., Takada M., Yoshida I., Azuma M. Microbiol. Immunol. 39:787-794(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: VR-3 EMBL BAA23729.2.
[2]	Suzutani T. Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: VR-3 EMBL BAA23729.2.
[3]	"HSV-1 TK variant from saliva." van Velzen M. Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 5 EMBL AFU56940.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	JQ895546 Genomic DNA. Translation: AFU56940.1. AB009254 Genomic DNA. Translation: BAA23729.2.
3D structure databases
HSSP	HSSP built from PDB template 1P7C based on UniProtKB P03176.
ProteinModelPortal	O55259.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001889. Herpes_TK. [Graphical view]
Pfam	PF00693. Herpes_TK. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O55259_HHV1

Accession

Primary (citable) accession number: O55259

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	October 1, 2001
Last modified:	April 3, 2013
This is version 37 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)