Unreviewed, UniProtKB/TrEMBL O55168 (O55168_RAT)

Names and origin

Protein names

Submitted name:
    Phosphatidylinositol 3-kinase EMBL BAA24030.1

Gene names

Name:

Pik3r1 RGD 3329

Organism

Rattus norvegicus (Rat) EMBL BAA24030.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	77 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Kinase EMBL BAA24030.1 Transferase
Gene Ontology (GO)
Biological process	B cell differentiation Inferred from electronic annotation. Source: Compara glucose metabolic process Inferred from mutant phenotype. Source: RGD insulin receptor signaling pathway Inferred from mutant phenotype. Source: RGD insulin-like growth factor receptor signaling pathway Inferred from mutant phenotype. Source: RGD negative regulation of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of cell-cell adhesion Inferred from mutant phenotype. Source: RGD negative regulation of cell-matrix adhesion Inferred from electronic annotation. Source: Compara negative regulation of osteoclast differentiation Inferred from electronic annotation. Source: Compara negative regulation of proteolysis Inferred from mutant phenotype. Source: RGD positive regulation of anti-apoptosis Inferred from mutant phenotype. Source: RGD positive regulation of cell migration Inferred from mutant phenotype. Source: RGD positive regulation of myoblast differentiation Inferred from mutant phenotype. Source: RGD protein amino acid phosphorylation Inferred from electronic annotation. Source: Compara response to cAMP Inferred from direct assay. Source: RGD response to estrogen stimulus Inferred from physical interaction. Source: RGD response to glucocorticoid stimulus Inferred from direct assay. Source: RGD
Cellular component	phosphoinositide 3-kinase complex Traceable author statement. Source: RGD plasma membrane Inferred from direct assay. Source: RGD
Molecular function	1-phosphatidylinositol-3-kinase activity Traceable author statement. Source: RGD insulin receptor substrate binding Inferred from physical interaction. Source: RGD phosphoinositide 3-kinase regulator activity Inferred from electronic annotation. Source: InterPro protein C-terminus binding Inferred from direct assay. Source: RGD protein domain specific binding Inferred from physical interaction. Source: RGD protein kinase binding Inferred from physical interaction. Source: RGD receptor binding Inferred from physical interaction. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAA24030.1
	Non-terminal residue	77	1	EMBL BAA24030.1

Sequences

	Sequence		Length	Mass (Da)
	O55168-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: ED78D4543A5F9582	FASTA	77	9,477
	10 20 30 40 50 60 QDQVVKEDNI EAVGKKLHEY NTQFQEKSRE YDRLYEEYTR TSQEIQMKRT AIEAFNETIK 70 IFEEQCQTQE RYSKEYI

References

[1]

"Gene expression of insulin signal-transduction pathway intermediates is lower in rats fed a beef tallow diet than in rats fed a safflower oil diet." Kim Y.-B., Nakajima R., Mastuo T., Inoue T., Sekine T., Komuro M., Tamura T., Tokuyama K., Suzuki M. Metabolism 45:1080-1088(1996) [PubMed: 8781294] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Sprague-Dawley EMBL BAA24030.1. Tissue: Skeletal muscle EMBL BAA24030.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D63325 mRNA. Translation: BAA24030.1.
IPI	IPI00211946.
UniGene	Rn.10599
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O55168.
Genome annotation databases
Ensembl	ENSRNOT00000025687; ENSRNOP00000025687; ENSRNOG00000018903; Rattus norvegicus. [Genome view] ENSRNOT00000065301; ENSRNOP00000060575; ENSRNOG00000018903; Rattus norvegicus. [Genome view]
Phylogenomic databases
HOVERGEN	O55168.
Gene expression databases
ArrayExpress	O55168.
Genevestigator	O55168.
Family and domain databases
InterPro	IPR001720. PI3kinase_P85. [Graphical view]
PANTHER	PTHR10155. PI3kinase_P85. 1 hit.
PRINTS	PR00678. PI3KINASEP85.
ProtoNet	Search...

Entry information

Entry name

O55168_RAT

Accession

Primary (citable) accession number: O55168

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)