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Protein

Growth arrest-specific protein 7

Gene

Gas7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Neurogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Growth arrest-specific protein 7
Short name:
GAS-7
Gene namesi
Name:Gas7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621550 Gas7

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000760591 – 422Growth arrest-specific protein 7Add BLAST422

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei62PhosphoserineBy similarity1
Modified residuei108PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO55148
PRIDEiO55148

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064359

Structurei

3D structure databases

ProteinModelPortaliO55148
SMRiO55148
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 55WWPROSITE-ProRule annotationAdd BLAST34
Domaini141 – 402F-BARPROSITE-ProRule annotationAdd BLAST262

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili254 – 329Sequence analysisAdd BLAST76

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0940 Eukaryota
KOG2398 Eukaryota
ENOG410Z5NV LUCA
HOGENOMiHOG000294146
HOVERGENiHBG001320
InParanoidiO55148
PhylomeDBiO55148

Family and domain databases

CDDicd07649 F-BAR_GAS7, 1 hit
Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR001060 FCH_dom
IPR037957 GAS7_F-BAR
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF00611 FCH, 1 hit
PF00397 WW, 1 hit
SMARTiView protein in SMART
SM00055 FCH, 1 hit
SM00456 WW, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF51045 SSF51045, 1 hit
PROSITEiView protein in PROSITE
PS51741 F_BAR, 1 hit
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

O55148-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATALQKPGM VPPPPGEESQ TVILPPGWHS YLSPQGRRYY VNTTTNETTW
60 70 80 90 100
ERPSSSPGIS ASPGPHRSSL PTTVNGYHAS GTPAHPPETA HMSLRKSTGD
110 120 130 140 150
SQNLGSSSPG RKQSKENTIT INCVTFPHPD TMPEQQLLKP TEWSYCDYFW
160 170 180 190 200
ADKKDPQGNG TVAGFELLLQ KQLKGKQMQK EMSEFIRERI KIEEEYAKNL
210 220 230 240 250
AKLSQNSLAA QEEGSLGEAW AQVKKSLADE AEVHLKFSAK LHSEVEKPLM
260 270 280 290 300
NFRENFKKDM KKCDHHIADL RKQLGESRYA SVEKARKALT ERQKDLEMKT
310 320 330 340 350
QQLEIKLSNK TEEDIKKARR KSTQAGDDLM RCVDLYNQAQ SKWFEEMVTT
360 370 380 390 400
TLELERLEVE RVEMIRQHLC QYTQLRHETD MFNQSTVEPV DQLLRKVDPA
410 420
KDRELWVREH KTGNIRPVDM EI
Length:422
Mass (Da):48,275
Last modified:January 11, 2001 - v2
Checksum:iFD14E4CB4DFB01F9
GO

Sequence cautioni

The sequence CAA05907 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAA10525 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ003148 mRNA Translation: CAA05907.1 Different initiation.
AJ131902 mRNA Translation: CAA10525.1 Different initiation.
UniGeneiRn.17160

Genome annotation databases

UCSCiRGD:621550 rat

Similar proteinsi

Entry informationi

Entry nameiGAS7_RAT
AccessioniPrimary (citable) accession number: O55148
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: January 11, 2001
Last modified: May 23, 2018
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health