Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Rattus norvegicus utrophin

Gene

Utrn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • actin filament binding Source: RGD
  • zinc ion binding Source: InterPro

GO - Biological processi

  • neuromuscular junction development Source: RGD
Complete GO annotation...

Keywords - Ligandi

Actin-bindingSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Rattus norvegicus utrophinImported
Gene namesi
Name:UtrnImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3947. Utrn.

Subcellular locationi

GO - Cellular componenti

  • cortical actin cytoskeleton Source: RGD
  • growth cone Source: RGD
  • neuromuscular junction Source: RGD
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO55147.
PRIDEiO55147.

PTM databases

iPTMnetiO55147.
PhosphoSitePlusiO55147.

Expressioni

Gene expression databases

GenevisibleiO55147. RN.

Interactioni

GO - Molecular functioni

  • actin filament binding Source: RGD

Protein-protein interaction databases

IntActiO55147. 2 interactors.
STRINGi10116.ENSRNOP00000016273.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3UULX-ray1.95A/B308-425[»]
3UUMX-ray2.00A/B308-430[»]
ProteinModelPortaliO55147.
SMRiO55147.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 135Actin-bindingInterPro annotationAdd BLAST105
Domaini150 – 252Actin-bindingInterPro annotationAdd BLAST103
Domaini2799 – 2832WWInterPro annotationAdd BLAST34
Domaini3051 – 3098ZZ-typeInterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili453 – 476Sequence analysisAdd BLAST24
Coiled coili879 – 906Sequence analysisAdd BLAST28
Coiled coili1099 – 1147Sequence analysisAdd BLAST49
Coiled coili2538 – 2572Sequence analysisAdd BLAST35
Coiled coili3240 – 3277Sequence analysisAdd BLAST38
Coiled coili3312 – 3342Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG4286. Eukaryota.
COG5069. LUCA.
HOGENOMiHOG000231173.
HOVERGENiHBG005495.

Family and domain databases

CDDicd00014. CH. 2 hits.
Gene3Di1.10.238.10. 2 hits.
1.10.418.10. 2 hits.
InterProiIPR001589. Actinin_actin-bd_CS.
IPR001715. CH-domain.
IPR011992. EF-hand-dom_pair.
IPR015153. EF-hand_dom_typ1.
IPR015154. EF-hand_dom_typ2.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
IPR001202. WW_dom.
IPR000433. Znf_ZZ.
[Graphical view]
PfamiPF00307. CH. 2 hits.
PF09068. EF-hand_2. 1 hit.
PF09069. EF-hand_3. 1 hit.
PF00435. Spectrin. 8 hits.
PF00569. ZZ. 1 hit.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
SM00150. SPEC. 19 hits.
SM00456. WW. 1 hit.
SM00291. ZnF_ZZ. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 2 hits.
SSF47576. SSF47576. 1 hit.
SSF51045. SSF51045. 1 hit.
PROSITEiPS00019. ACTININ_1. 1 hit.
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O55147-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKYGHLEAS PDDGQNQFSD IIKSRSDEHN DVQKKTFTKW INARFSKSGK
60 70 80 90 100
PPINDMFSDL KDGRKLLDLL EGLTGTSLPK ERGSTRVHAL NNVNRVLQVL
110 120 130 140 150
HQNNVELVNI GGTDIVDGNP KLTLGLLWSI ILHWQVKDVM KDIMSDLQQT
160 170 180 190 200
NSEKILLSWV RQTTRPYSQV NVLNFTTSWT DGLAFNAVLH RHKPDLFSWD
210 220 230 240 250
RVVKMSPTER LEHAFSKAHT YLGIEKLLDP EDVAVQLPDK KSIIMYLTSL
260 270 280 290 300
FEVLPQQVTI DAIREVETLP RKYKKECEGE EINIQSAVLT EEGQSPRAET
310 320 330 340 350
PSTVTEVDMD LDSYQIALEE VLTWLLSAED TFQEQDDISD DVEDVKEQFA
360 370 380 390 400
THETFMMELS AHQSSVGSVL QAGNQLMTQG TLSDEEEFEI QEQMTLLNAR
410 420 430 440 450
WEALRVESME RQSRLHDALM ELQKKQLQQL SGWLTLTEER IQKMESLPVG
460 470 480 490 500
DDLPSLQNLL EEHKSLQSDL EAEQVKVNSL THMVVIVDEN SGESATAVLE
510 520 530 540 550
DQLQKLGERW TAVCRWTEER WNRLQEINIL WQELLEEQCL LEAWLTEKEE
560 570 580 590 600
ALNKVQTGNF KDQKELGVSV RRLAILKEDM EMKRQTLDQL SEIGQDVGQL
610 620 630 640 650
LSNPKASEKM NSDSEELTQR WDSLVQRLED SSNQVTQAVA KLGMSQIPQK
660 670 680 690 700
DLLETVHVRE QGMIKKPKQE LPPPPPPKKR QIHVDVEAKK KFDATSAELQ
710 720 730 740 750
SWILRSKAAL QNTEMNEYKK SQETSGVRKK WKGLEKEQKE KIPQLDELNQ
760 770 780 790 800
TGQILQEQMG KEGLLAEEIN DVLERVLLEW KMISQQLEDL GRKIQLQEDI
810 820 830 840 850
NAYFRQLDAL EKTIRAKEEW LRDASFSESP QRSLPSLKDS CQRELTDLLG
860 870 880 890 900
LHPRIEILCA SCSALRSQPS VPGFVQQGFD DLRRHYQAVQ KALEEYQQQL
910 920 930 940 950
ENELKSQPEP AYLDTLNTLK KMLSESEKAA QASLSALNDP SAVEQALQEK
960 970 980 990 1000
KALDETLENQ KPTLHKLSEE TKALEKNMLP DVGKTYRQEF DDAQGKWNKV
1010 1020 1030 1040 1050
KTKVSRDLRS LEEIIPRLRD FKADSEVIEK WTNGVKDFLM KEQAAQGDTT
1060 1070 1080 1090 1100
ALQRQLDQCT TFANEIETIE SSLKNLRDIE TSLQRCPVTG VKTWVQTRLA
1110 1120 1130 1140 1150
DYQSQLEKFS QEIDIQKSRL SDSQEKAMNL KKDLAEMQEW MAQAEEDYLE
1160 1170 1180 1190 1200
RDFEYKSPEE LESAVEEMKR AKEDVLQKEV RVKILKDSIK LVAARVPSGG
1210 1220 1230 1240 1250
QELTSEFNEV LESYQLLCNR IRGKCHTLEE VWSCWVELLH YLDLETAWLN
1260 1270 1280 1290 1300
TLEERMQSTE ALPERAEAVH DALESLESVL RHPADNRTQI RELGQTLIDG
1310 1320 1330 1340 1350
GILDDIISEK LEAFNSRYEE LSHLAESKQI SLEKQLQVLR ETDHMLQVLK
1360 1370 1380 1390 1400
ESLGELDKQL TTYLTDRIDA FQLPQEAQKI QAEISAHELT LEELKKNVRP
1410 1420 1430 1440 1450
QPPTSPEGRT TRGGSQMDLL QRKLREVSTK FQLFQKPANF EQRMLDCKRV
1460 1470 1480 1490 1500
LDGVKAELHV LSVKDVDPDV IQTHLDKCMK LYKTLSEVKL EVETVIKTGR
1510 1520 1530 1540 1550
HIVQKQQTDN PKGMDEQLTS LKVLYNDLGA QVTEGKQDLE RASQLSRKLK
1560 1570 1580 1590 1600
KEAAILSEWL STTEAELVQK SASEGVIGDL DTEISWAKNI LKDLEKRKVD
1610 1620 1630 1640 1650
LNTITESSAA LQHLVVGSES VLEDTLCVLN AGWSRVRTWT EDWRNTLLNH
1660 1670 1680 1690 1700
QNQLEVFDGH VAHISTCLYQ AEALLDEIEK KPASKQEEIV KRLLSELSDA
1710 1720 1730 1740 1750
SIQVENVREQ AIVLVNARGS SSRELVEPKL AELGKNFEKV SQHINSAQML
1760 1770 1780 1790 1800
IGQDPAGTVE AVGPFSDLES LESDIENMLK VVEKHLDPSN DEKMDEERAQ
1810 1820 1830 1840 1850
IEEVLQRGEH LLHEPMEDSK KEKIRLQLLL LHTRYNKIKA IPQRKTIPLS
1860 1870 1880 1890 1900
SGIMSSALPA DYLVEINKIL LTLDDIELSL NIPELNTTVY EDFSFQEDSL
1910 1920 1930 1940 1950
KRIKDQLDRL GEQLAAVHEK QPDVILEASG PEAIQIRDML SQLNAKWDRV
1960 1970 1980 1990 2000
NRLYSDRRGS FARAVEEWKQ FHCDLDDLTQ WLSEAEDLLV GTCAPDGSLD
2010 2020 2030 2040 2050
LEKARTHQLE LEDGLSSHQP CLIDVNQKGE DIVQRLRPSD ASFLKDKLAS
2060 2070 2080 2090 2100
LNQRWSALVA EVKDLQPRLK GESKQVSGYR KRLDEVVCWL TKVENSVQKR
2110 2120 2130 2140 2150
STPDPEENPW ELTDLAQEMD AQAENIKWLN RAELEMLSDK NLSLCERDNL
2160 2170 2180 2190 2200
SESLRNVNTM WTKICREVPS LLKTRTQDPC SAPQTRIAAH PNVQKVALVS
2210 2220 2230 2240 2250
SASDAPLRGP EISVPADLDK TITELADWLV LIDQMLKSNI VTVGDVKEIN
2260 2270 2280 2290 2300
KTVSRMKITK ADLEQRHPQL DFVFTLAQNL KNKASSSDLR TAITGKLEKL
2310 2320 2330 2340 2350
KTQWESTQHG VELRRQQLED MVVDSLQWDD HREETEELMR KHEARFYMLQ
2360 2370 2380 2390 2400
QARRDPLSKQ VSDNQLLLQE LGSGDGVIMA FDNVLQKLLE EYSSDDTRNV
2410 2420 2430 2440 2450
EETTEYLKTS WINLKQSIAD RQSALEAELR TVQTSRRDLE NFVKWLQEAE
2460 2470 2480 2490 2500
TTANVLADAS QRENALQDSV LARQLRQQML DIQAEIDAHN DIFKSIDGNR
2510 2520 2530 2540 2550
QKMVKALGNS EEATMLQHRL DDMNQRWNDL KAKSASIRAH LEASAEKWNR
2560 2570 2580 2590 2600
LLASLEELIK WLNMKDEELK KQMPIGGDVP ALQLQYDHCK VLRRELKEKE
2610 2620 2630 2640 2650
YSVLNAVDQA RVFLADQPIE APEEPRRNPQ SKTELTPEER AQKIAKAMRK
2660 2670 2680 2690 2700
QSSEVREKWE SLNAVTSTWQ KQVGKALEKL RDLQGAVDDL DADMKEVEAV
2710 2720 2730 2740 2750
RNGWKPVGDL LIDSLQDHIE KTLAFREEIA PINLKVKTMN DLSSQLSPLD
2760 2770 2780 2790 2800
LHPSPKMSRQ LDDLNMRWKL LQVSVEDRLK QLQEAHRDFG PCSQHFLSTS
2810 2820 2830 2840 2850
VQLPWQRSIS HNKVPYYINH QTQTTCWDHP KMTELFQSLG DLNNVRFSAY
2860 2870 2880 2890 2900
RTAIKIRRLQ KALCLDLLEL NTTNEVFKQH KLNQNDQLLS VPDVINCLTT
2910 2920 2930 2940 2950
TYDGLEQLHK DLVNVPLCVD MCLNWLLNVY DTGRTGKIRV QSLKIGLMSL
2960 2970 2980 2990 3000
SKGLLEEKYR CLFKEVAGPT EMCDQRQLGL LLHDAIQIPR QLGEVAAFGG
3010 3020 3030 3040 3050
SNIEPSVRSC FQQNNNKPEI SVKEFIDWMR LEPQSMVWLP VLHRVAAAET
3060 3070 3080 3090 3100
AKHQAKCNIC KECPIVGFRY RSLKHFNYDV CQSCFFSGRT AKGHKLHYPM
3110 3120 3130 3140 3150
VEYCIPTTSG EDVRDFTKVL KNKFRSKKYF AKHPRLGYLP VQTVLEGDNL
3160 3170 3180 3190 3200
ETPITLISMW PEHYDPSQSP QLFHDDTHSR IEQYATRLAQ MERTNGSFLT
3210 3220 3230 3240 3250
DSSSTTGSVE DEHALIQQYC QTLGGESPVS QPQSPAQILK SVEKEERGEL
3260 3270 3280 3290 3300
ERIIADLEEE QRNLQVEYEQ LKEQHLRRGL PLGSPPDSIV SPHHTSEDSE
3310 3320 3330 3340 3350
LIAEAKLLRQ HKGRLEARMQ ILEDHNKQLE SQLHRLRQLL EQPDSDSRIN
3360 3370 3380 3390 3400
GVSPWASPQH PSLSYSLDPD PGPQSHQAAS EDLLAPPHDT STDLTDVMEQ
3410
LNSTFPSCSP NVPSRPQAI
Length:3,419
Mass (Da):391,075
Last modified:June 1, 1998 - v1
Checksum:i74CF4ECC19EC5E63
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002967 mRNA. Translation: CAA05775.1.
RefSeqiNP_037202.1. NM_013070.1.
UniGeneiRn.9901.

Genome annotation databases

GeneIDi25600.
KEGGirno:25600.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002967 mRNA. Translation: CAA05775.1.
RefSeqiNP_037202.1. NM_013070.1.
UniGeneiRn.9901.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3UULX-ray1.95A/B308-425[»]
3UUMX-ray2.00A/B308-430[»]
ProteinModelPortaliO55147.
SMRiO55147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO55147. 2 interactors.
STRINGi10116.ENSRNOP00000016273.

PTM databases

iPTMnetiO55147.
PhosphoSitePlusiO55147.

Proteomic databases

PaxDbiO55147.
PRIDEiO55147.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi25600.
KEGGirno:25600.

Organism-specific databases

CTDi7402.
RGDi3947. Utrn.

Phylogenomic databases

eggNOGiKOG4286. Eukaryota.
COG5069. LUCA.
HOGENOMiHOG000231173.
HOVERGENiHBG005495.

Gene expression databases

GenevisibleiO55147. RN.

Family and domain databases

CDDicd00014. CH. 2 hits.
Gene3Di1.10.238.10. 2 hits.
1.10.418.10. 2 hits.
InterProiIPR001589. Actinin_actin-bd_CS.
IPR001715. CH-domain.
IPR011992. EF-hand-dom_pair.
IPR015153. EF-hand_dom_typ1.
IPR015154. EF-hand_dom_typ2.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
IPR001202. WW_dom.
IPR000433. Znf_ZZ.
[Graphical view]
PfamiPF00307. CH. 2 hits.
PF09068. EF-hand_2. 1 hit.
PF09069. EF-hand_3. 1 hit.
PF00435. Spectrin. 8 hits.
PF00569. ZZ. 1 hit.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
SM00150. SPEC. 19 hits.
SM00456. WW. 1 hit.
SM00291. ZnF_ZZ. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 2 hits.
SSF47576. SSF47576. 1 hit.
SSF51045. SSF51045. 1 hit.
PROSITEiPS00019. ACTININ_1. 1 hit.
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO55147_RAT
AccessioniPrimary (citable) accession number: O55147
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.