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Protein

Protein NipSnap homolog 1

Gene

Nipsnap1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • neurotransmitter binding Source: MGI

GO - Biological processi

  • sensory perception of pain Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NipSnap homolog 1
Short name:
NipSnap1
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1278344. Nipsnap1.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: MGI
  • mitochondrial inner membrane Source: MGI
  • mitochondrion Source: UniProtKB
  • synaptic membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002211471 – 284Protein NipSnap homolog 1Add BLAST284

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei65N6-acetyllysineCombined sources1
Modified residuei66N6-acetyllysineCombined sources1
Modified residuei73N6-acetyllysineCombined sources1
Modified residuei80N6-acetyllysineCombined sources1
Modified residuei129PhosphoserineBy similarity1
Modified residuei143N6-acetyllysineCombined sources1
Modified residuei146N6-acetyllysine; alternateCombined sources1
Modified residuei146N6-succinyllysine; alternateCombined sources1
Modified residuei191N6-acetyllysineCombined sources1
Modified residuei193N6-acetyllysine; alternateCombined sources1
Modified residuei193N6-succinyllysine; alternateCombined sources1
Modified residuei279N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiO55125.
PaxDbiO55125.
PeptideAtlasiO55125.
PRIDEiO55125.

PTM databases

iPTMnetiO55125.
PhosphoSitePlusiO55125.
SwissPalmiO55125.

Expressioni

Gene expression databases

BgeeiENSMUSG00000034285.
ExpressionAtlasiO55125. baseline and differential.
GenevisibleiO55125. MM.

Interactioni

Protein-protein interaction databases

BioGridi201774. 1 interactor.
IntActiO55125. 4 interactors.
MINTiMINT-1859805.
STRINGi10090.ENSMUSP00000049338.

Structurei

3D structure databases

ProteinModelPortaliO55125.
SMRiO55125.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NipSnap family.Curated

Phylogenomic databases

eggNOGiKOG2883. Eukaryota.
ENOG410XSWP. LUCA.
GeneTreeiENSGT00730000110910.
HOGENOMiHOG000194298.
HOVERGENiHBG052627.
InParanoidiO55125.
OMAiAFSYWPQ.
OrthoDBiEOG091G0G3J.
PhylomeDBiO55125.
TreeFamiTF314501.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR012577. NIPSNAP.
[Graphical view]
PfamiPF07978. NIPSNAP. 1 hit.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 2 hits.

Sequencei

Sequence statusi: Complete.

O55125-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRLCIISA AARRLFTKPR PRAGDLAAAG AVRFYSKDSE GSWFRSLFVH
60 70 80 90 100
KVDPRKDAHS TLLSKKETSN LYKIQFHNVK PECLDAYNSL TEAVLPKLHL
110 120 130 140 150
DEDYPCSLVG NWNTWYGEQD QAVHLWRFSG GYPALMDCMN KLKNNKEYLE
160 170 180 190 200
FRKERSKMLL SRRNQLLLEF SFWNEPQPRA GPNIYELRTY KLKPGTMIEW
210 220 230 240 250
GNNWARAIKY RQENQEAVGG FFSQIGELYV VHHLWAYKDL QSREETRNAA
260 270 280
WRKRGWDENV YYTVPLVRHM ESRIMIPLKI SPLQ
Length:284
Mass (Da):33,363
Last modified:June 1, 1998 - v1
Checksum:iE96EA869A58BC3F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001260 mRNA. Translation: CAA04634.1.
BC010837 mRNA. Translation: AAH10837.1.
CCDSiCCDS24392.1.
RefSeqiNP_032724.1. NM_008698.2.
UniGeneiMm.293716.

Genome annotation databases

EnsembliENSMUST00000038570; ENSMUSP00000049338; ENSMUSG00000034285.
GeneIDi18082.
KEGGimmu:18082.
UCSCiuc007hvk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001260 mRNA. Translation: CAA04634.1.
BC010837 mRNA. Translation: AAH10837.1.
CCDSiCCDS24392.1.
RefSeqiNP_032724.1. NM_008698.2.
UniGeneiMm.293716.

3D structure databases

ProteinModelPortaliO55125.
SMRiO55125.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi201774. 1 interactor.
IntActiO55125. 4 interactors.
MINTiMINT-1859805.
STRINGi10090.ENSMUSP00000049338.

PTM databases

iPTMnetiO55125.
PhosphoSitePlusiO55125.
SwissPalmiO55125.

Proteomic databases

EPDiO55125.
PaxDbiO55125.
PeptideAtlasiO55125.
PRIDEiO55125.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038570; ENSMUSP00000049338; ENSMUSG00000034285.
GeneIDi18082.
KEGGimmu:18082.
UCSCiuc007hvk.1. mouse.

Organism-specific databases

CTDi8508.
MGIiMGI:1278344. Nipsnap1.

Phylogenomic databases

eggNOGiKOG2883. Eukaryota.
ENOG410XSWP. LUCA.
GeneTreeiENSGT00730000110910.
HOGENOMiHOG000194298.
HOVERGENiHBG052627.
InParanoidiO55125.
OMAiAFSYWPQ.
OrthoDBiEOG091G0G3J.
PhylomeDBiO55125.
TreeFamiTF314501.

Miscellaneous databases

ChiTaRSiNipsnap1. mouse.
PROiO55125.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034285.
ExpressionAtlasiO55125. baseline and differential.
GenevisibleiO55125. MM.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR012577. NIPSNAP.
[Graphical view]
PfamiPF07978. NIPSNAP. 1 hit.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiNIPS1_MOUSE
AccessioniPrimary (citable) accession number: O55125
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.