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Protein
Submitted name:

M-protein

Gene

Myom2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • structural constituent of cytoskeleton Source: MGI

GO - Biological processi

  • muscle contraction Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
M-proteinImported
Gene namesi
Name:Myom2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1328358. Myom2.

Subcellular locationi

GO - Cellular componenti

  • cytoskeleton Source: MGI
  • M band Source: MGI
  • mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO55124.
PRIDEiO55124.

Expressioni

Gene expression databases

GenevisibleiO55124. MM.

Interactioni

Protein-protein interaction databases

IntActiO55124. 1 interaction.
MINTiMINT-4105158.
STRINGi10090.ENSMUSP00000033842.

Structurei

3D structure databases

ProteinModelPortaliO55124.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini154 – 24592Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini266 – 35489Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini385 – 48096Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini513 – 60896Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini614 – 70794Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini710 – 812103Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini815 – 91298Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini904 – 100299Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini1130 – 121182Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini1358 – 143477Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili101 – 12828Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IJ5G. Eukaryota.
ENOG410ZSRR. LUCA.
HOGENOMiHOG000293283.
HOVERGENiHBG004977.

Family and domain databases

Gene3Di2.60.40.10. 12 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF00041. fn3. 5 hits.
PF07679. I-set. 3 hits.
[Graphical view]
SMARTiSM00060. FN3. 5 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 3 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 6 hits.
SSF49265. SSF49265. 3 hits.
PROSITEiPS50853. FN3. 5 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O55124-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLVAVPFYQ KRHKHFDQSY RNIQTRYLLD QYALKKQATT QSSSQRSLTE
60 70 80 90 100
RSSSKRASSQ SSAGAMTCRL CAKRVSASEE EEVENENRYR SQAASYGEAK
110 120 130 140 150
RQRFLSELAQ LEENVHLARS QARDKLDKYF LEQTVEDNLA WERHSFEDRM
160 170 180 190 200
SRAPEILVRL RSHTIWERMS VRLCFTVQGF PTPVVQWYKD GSLICQAGEP
210 220 230 240 250
GKYRIKSRYG VHTLEINRAN FEDTATYSAV ATNSHEQVST NAAVVVRRYR
260 270 280 290 300
GEEEPFHSVG LPIGLPLSSV IPYTHFDVQI FGVFGVTFGG EGETVTLKCT
310 320 330 340 350
LLVTPDLRRV QPRAEWYRDD VLLKESKWTK MFFGEGQASL SFSHLNKDDE
360 370 380 390 400
GLYTLRIVSR GGVSDHSAFM FVRDADPLVT GAPGAPMDLQ CHDANRDYVI
410 420 430 440 450
VTWKPPNTTT ESPVIGYFID KCEVGTNNWV QCNDAPVKIC KYPVTGLFEG
460 470 480 490 500
RSYVFRVRAV NNAGISRPSR ISDAVAALDP VDLRRLQAIH LEGEKEIVIY
510 520 530 540 550
QDDLEGDVQI PGPPTNVQAS EVSRNYVVLS WDPPSPRGKD PLMYFIEKSA
560 570 580 590 600
VGSGSWQRVN AQTAVRSPRY AVFDLAEGKS YVFRVLSANK HGLSDPSEIT
610 620 630 640 650
PPIQAQDMIV VPSAPGRVLA SRNTKTSVVV QWDRPKHEED LLGYYVDCCV
660 670 680 690 700
AGTNMWEPCN HKPIGYNRFV VHGLTTGEQY IFRVKAVNAV GTSENSQESE
710 720 730 740 750
VIKVQAALTV PSHPYGITLL NCDGHSMTLG WKVPKFSGGS AIIGYYLDKR
760 770 780 790 800
EVHHKNWHEV NSSPVKERIL TVEGLTEGSL YEFKIAATNL AGIGQPSDPS
810 820 830 840 850
EHFKCEAWTD PEPGPAYDLT FCEVRDTSLV ILWKAPVYSG SSPVSGYFVD
860 870 880 890 900
FKEEDSGEWK TTSEAATPNR YLKVCDLQQG KTYVFRIRAV NASGPGKPSD
910 920 930 940 950
TSEPVLVEAR PGTKEISAGV DEEGNIYLGF DCQEMTDASQ FTWCKAYEEI
960 970 980 990 1000
ADEERFEVHT EGDHSKLYFK NPDKEDIGTY SVSVSDTDGV SSSFVLDEEE
1010 1020 1030 1040 1050
LERLMALSNE IKNPTIPLKS ELAYEIFDKG QVRFWLQAEH LSPDASFRFI
1060 1070 1080 1090 1100
INDREVSDSD THRIKCDRST GMIEMVMDRF TIENEGTYTV QIQDGKAKNQ
1110 1120 1130 1140 1150
SSLVLIGDAF KAVLEEAEFQ RKEFLRKQGP HFAEYLHWDV TEECEVRLVC
1160 1170 1180 1190 1200
KVANTKRETV FKWLKDDVLY ETETPPDLEK GVCELLIPKL SKKDHGEYKA
1210 1220 1230 1240 1250
TLKDDRGQDV SVLEVGGKVY EDMILAMSRV CGASASPLKV LCTPEGIRLQ
1260 1270 1280 1290 1300
CFMKYFTEEM KVSWYHKEAK ISSSEHMRIG GSEEMAWLQI CEPTEKDKGK
1310 1320 1330 1340 1350
YTFEIFDGKD SHQRSLDLSG QAFDEAYAEF QQLKAAAFAE KNRGKVIGGL
1360 1370 1380 1390 1400
PDVVTIMEGK TLNLTCTVFG NPDPEVVWFK NDKDIELSEH FLVKMEQSKY
1410 1420 1430 1440 1450
VSLTIQGVTA EDSGKYSINV KNKYGGEKID VTVSVYKHGE KIPDISPPQQ
1460
AKPKLIPAST SSD
Length:1,463
Mass (Da):164,519
Last modified:June 1, 1998 - v1
Checksum:i8C6551ED90F0B288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001038 mRNA. Translation: CAA04492.1.
RefSeqiNP_032690.2. NM_008664.2.
UniGeneiMm.272115.

Genome annotation databases

GeneIDi17930.
KEGGimmu:17930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001038 mRNA. Translation: CAA04492.1.
RefSeqiNP_032690.2. NM_008664.2.
UniGeneiMm.272115.

3D structure databases

ProteinModelPortaliO55124.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO55124. 1 interaction.
MINTiMINT-4105158.
STRINGi10090.ENSMUSP00000033842.

Proteomic databases

PaxDbiO55124.
PRIDEiO55124.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17930.
KEGGimmu:17930.

Organism-specific databases

CTDi9172.
MGIiMGI:1328358. Myom2.

Phylogenomic databases

eggNOGiENOG410IJ5G. Eukaryota.
ENOG410ZSRR. LUCA.
HOGENOMiHOG000293283.
HOVERGENiHBG004977.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevisibleiO55124. MM.

Family and domain databases

Gene3Di2.60.40.10. 12 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF00041. fn3. 5 hits.
PF07679. I-set. 3 hits.
[Graphical view]
SMARTiSM00060. FN3. 5 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 3 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 6 hits.
SSF49265. SSF49265. 3 hits.
PROSITEiPS50853. FN3. 5 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structure and expression of the gene encoding murine M-protein, a sarcomere-specific member of the immunoglobulin superfamily."
    Steiner F., Weber K., Fuerst D.O.
    Genomics 49:83-95(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO55124_MOUSE
AccessioniPrimary (citable) accession number: O55124
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.