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Protein
Submitted name:

Brain natriuretic peptide

Gene

BNP

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Keywordsi

Molecular functionVasoactiveUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Brain natriuretic peptideImported
Submitted name:
Natriuretic peptide type BImported
Gene namesi
Name:BNPImported
Synonyms:NppbImported
ORF Names:mCG_11731Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500769697727 – 121Sequence analysisAdd BLAST95

Proteomic databases

PRIDEiO55086.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099521.

Family & Domainsi

Sequence similaritiesi

Belongs to the natriuretic peptide family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J2F8. Eukaryota.
ENOG410ZE1B. LUCA.
HOVERGENiHBG004227.

Family and domain databases

InterProiView protein in InterPro
IPR000663. Natr_peptide.
IPR030480. Natr_peptide_CS.
IPR002408. Natriuretic_peptide_brain.
PfamiView protein in Pfam
PF00212. ANP. 1 hit.
PRINTSiPR00712. BNATPEPTIDE.
SMARTiView protein in SMART
SM00183. NAT_PEP. 1 hit.
PROSITEiView protein in PROSITE
PS00263. NATRIURETIC_PEPTIDE. 1 hit.

Sequencei

Sequence statusi: Complete.

O55086-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLLKVLSQM ILFLLFLYLS PLGGHSHPLG SPSQSPEQFK MQKLLELIRE
60 70 80 90 100
KSEEMAQRQL LKDQGLTKEH PKRVLRSQGS TLRVQQRPQN SKVTHISSCF
110 120
GHKIDRIGSV SRLGCNALKL L
Length:121
Mass (Da):13,730
Last modified:June 1, 1998 - v1
Checksum:i54781D3F445283B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D82049 Genomic DNA. Translation: BAA24159.1.
AB039045 Genomic DNA. Translation: BAB68569.1.
AB039046 Genomic DNA. Translation: BAB68570.1.
AB039048 Genomic DNA. Translation: BAB68572.1.
AB039049 Genomic DNA. Translation: BAB68573.1.
AB039050 Genomic DNA. Translation: BAB68574.1.
CH466594 Genomic DNA. Translation: EDL14790.1.
UniGeneiMm.2740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D82049 Genomic DNA. Translation: BAA24159.1.
AB039045 Genomic DNA. Translation: BAB68569.1.
AB039046 Genomic DNA. Translation: BAB68570.1.
AB039048 Genomic DNA. Translation: BAB68572.1.
AB039049 Genomic DNA. Translation: BAB68573.1.
AB039050 Genomic DNA. Translation: BAB68574.1.
CH466594 Genomic DNA. Translation: EDL14790.1.
UniGeneiMm.2740.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099521.

Proteomic databases

PRIDEiO55086.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410J2F8. Eukaryota.
ENOG410ZE1B. LUCA.
HOVERGENiHBG004227.

Family and domain databases

InterProiView protein in InterPro
IPR000663. Natr_peptide.
IPR030480. Natr_peptide_CS.
IPR002408. Natriuretic_peptide_brain.
PfamiView protein in Pfam
PF00212. ANP. 1 hit.
PRINTSiPR00712. BNATPEPTIDE.
SMARTiView protein in SMART
SM00183. NAT_PEP. 1 hit.
PROSITEiView protein in PROSITE
PS00263. NATRIURETIC_PEPTIDE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO55086_MOUSE
AccessioniPrimary (citable) accession number: O55086
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: October 5, 2016
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.