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Protein
Submitted name:

Cis-retinol androgen dehydrogenase 1

Gene

Rdh16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • protein homodimerization activity Source: MGI
  • retinol dehydrogenase activity Source: MGI

GO - Biological processi

  • 9-cis-retinoic acid biosynthetic process Source: MGI

Enzyme and pathway databases

BRENDAi1.1.1.315. 3474.
ReactomeiR-MMU-5365859. RA biosynthesis pathway.

Chemistry databases

SwissLipidsiSLP:000000799.

Names & Taxonomyi

Protein namesi
Submitted name:
Cis-retinol androgen dehydrogenase 1Imported
Submitted name:
MCG17020Imported
Submitted name:
Retinol dehydrogenase 16Imported
Gene namesi
Name:Rdh16Imported
Synonyms:Rdh6Imported
ORF Names:mCG_17020Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1201375. Rdh16.

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum lumen Source: MGI
  • integral component of organelle membrane Source: MGI

Expressioni

Gene expression databases

BgeeiENSMUSG00000069456.

Interactioni

GO - Molecular functioni

  • protein homodimerization activity Source: MGI

Protein-protein interaction databases

MINTiMINT-1862300.
STRINGi10090.ENSMUSP00000071573.

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1610. Eukaryota.
ENOG410Y7FK. LUCA.
GeneTreeiENSGT00890000139345.
HOVERGENiHBG005482.
KOiK11154.
OMAiMPTCVSD.
OrthoDBiEOG091G0LMI.
TreeFamiTF325617.

Family and domain databases

InterProiView protein in InterPro
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
PfamiView protein in Pfam
PF00106. adh_short. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 2 hits.
PROSITEiView protein in PROSITE
PS00061. ADH_SHORT. 1 hit.

Sequencei

Sequence statusi: Complete.

O54909-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLYLVALVG LWTLLRFFRV RQVVSHLQDK YVFITGCDSG FGTLLARQLD
60 70 80 90 100
RRGMRVLAAC LTEKGAEELR NKTSDRLETV ILDVTKTESI VTATQWVKEH
110 120 130 140 150
VGNRGLWGLV NNAGISTPSG PNEWMKKQDF AHVLDVNLLG MIEVTLSMLP
160 170 180 190 200
LVRKARGRVV NVSSVMGRVS LFGGGYCISK YGVEAFSDSL RRELSYFGVK
210 220 230 240 250
VAIIEPGFFL TGVTSSARLC SNTQMLWDQT SSEIREIYGE KYLASYLKRL
260 270 280 290 300
NKLDKRCNKD LSGVTDCMEH ALTACHPRTR YSAGWDAKLF YLPLSYLPTF
310
LVDALLYWTS LKPEKAL
Length:317
Mass (Da):35,744
Last modified:June 1, 1998 - v1
Checksum:iB3D82F3F1D5D57C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131690 Genomic DNA. No translation available.
AF030513 mRNA. Translation: AAB97166.1.
BC089612 mRNA. Translation: AAH89612.1.
CH466578 Genomic DNA. Translation: EDL24525.1.
RefSeqiNP_033066.1. NM_009040.3.
XP_006513452.1. XM_006513389.2.
UniGeneiMm.100276.

Genome annotation databases

EnsembliENSMUST00000071646; ENSMUSP00000071573; ENSMUSG00000069456.
GeneIDi19683.
KEGGimmu:19683.
UCSCiuc007hkq.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiO54909_MOUSE
AccessioniPrimary (citable) accession number: O54909
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: August 30, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported