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O54892

- O54892_RAT

UniProt

O54892 - O54892_RAT

Protein
Submitted name:

Mutant type II hexokinase

Gene

Hk2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Jun 1998)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. hexokinase activity Source: InterPro

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mutant type II hexokinaseImported
    Gene namesi
    Name:Hk2Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi2797. Hk2.

    PTM / Processingi

    Proteomic databases

    PRIDEiO54892.

    Expressioni

    Gene expression databases

    GenevestigatoriO54892.

    Structurei

    3D structure databases

    ProteinModelPortaliO54892.
    SMRiO54892. Positions 17-913.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG005020.
    InParanoidiO54892.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O54892-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIASHMIACL FTELNQNQVQ KVDQFLYHMR LSDETLLEIS RRFRKEMEKG    50
    LGATTHPTAA VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLRVRVTDN 100
    GLQRVEMENQ IYAILEDIMR GSGTQLFDHI AECLANFMDK LQIKEKKLPL 150
    GFTFSFPCHQ TKLDESFLVS WTKGFKSSGV EGRDVVDLIR KVIQRRGDFD 200
    IDIVAVVNDT VGTMMTCGYD DQNCEIGLIV GTGSNACYME EMRHIDMVEG 250
    DEGRMCINME WGAFGDDGTL NDIRTEFDRE IDMGSLNPGK QLFEKMISGM 300
    YMGELVRLIL VKMAKAELLF QGKLSPELLT TGSFETKDVS DIEEDKDGIE 350
    KAYQILMRLG LNPLQEDCVA THRICQIVST RSASLCAATL AAVLWRIKEN 400
    KGEERLRSTI GVDGSVYKKH PHFAKRLHKA VRRLVPDCDV RFLRSEDGSG 450
    KGAAMVTAVA YRLADQHRAR QKTLESLKLS HEQLLEVKRR MKVEMEQGLS 500
    KETHAVAPVK MLPTYVCATP DGTEKGDFLA LDLGGTNFRV LLVRVRNGKR 550
    RGVEMHNKIY SIPQEVMHGT GEELFDHIVQ CIADFLEYMG MKGVSLPLGF 600
    TFSFPCQQNS LDQSILLKWT KGFKASGCEG EDVVTLLKEA IHRREEFDLD 650
    VVAVVNDTVG TMMTCGYEDP HCEVGLIVGT GSNACYMEEM RNVELVDGEE 700
    GRMCVNMEWG AFGDNGCLDD LRTVFDVAVD ELSLNPGKQR FEKMISGMYL 750
    GEIVRNILID FTKRGLLFRG RISERLKTRG ISETKFLSQI ESDCLALLQV 800
    RAILRHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG 850
    LDNPKVTVGV DGTLYKLHPH FAKVMHETVR DLAPKCDVSF LESEDGSGKG 900
    AALITAVACR IREAGQR 917
    Length:917
    Mass (Da):102,512
    Last modified:June 1, 1998 - v1
    Checksum:iC3C2AAB8037CF73E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF027179 mRNA. Translation: AAB91396.1.
    UniGeneiRn.91375.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF027179 mRNA. Translation: AAB91396.1 .
    UniGenei Rn.91375.

    3D structure databases

    ProteinModelPortali O54892.
    SMRi O54892. Positions 17-913.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O54892.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 2797. Hk2.

    Phylogenomic databases

    HOVERGENi HBG005020.
    InParanoidi O54892.

    Gene expression databases

    Genevestigatori O54892.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Type II Hexokinase of Hepatoma AS-30D."
      Mathupala S.P.
      Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiO54892_RAT
    AccessioniPrimary (citable) accession number: O54892
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 1998
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)