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Protein
Submitted name:

Kallikrein 6, isoform CRA_a

Gene

Klk6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • peptidase activity Source: RGD
  • serine-type endopeptidase activity Source: Ensembl

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPSiS01.236

Names & Taxonomyi

Protein namesi
Submitted name:
Kallikrein 6, isoform CRA_aImported
Submitted name:
Myelencephalon specific proteaseImported
Submitted name:
Prostatic glandular kallikrein-6Imported
Gene namesi
Name:Klk6Imported
ORF Names:rCG_54275Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi3419 Klk6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501410204924 – 251Sequence analysisAdd BLAST228

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000031927

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060676

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 249Peptidase S1InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118862
HOGENOMiHOG000251820
HOVERGENiHBG013304
KOiK08667
OMAiAWAEEQN
OrthoDBiEOG091G0G5F

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

O54854-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTKMLTVKT LALCLILAKS AWSEDQDKVV HGGPCLKNSH PFQAALYTSG
60 70 80 90 100
HLLCGGVLVG PQWVLTAAHC KKPNLEVYLG KHNLRQTETF QRQISVDRTI
110 120 130 140 150
VHPRYNPQTH DNDIMMVHLK RPVKFSQRIQ PLPLKKDCSE KNPDCQILGW
160 170 180 190 200
GKMENGEFPD TIQCADVQLV SREECERAYP GKITRSMVCA GDKREGNDSC
210 220 230 240 250
QGDSGGPLVC GGHLRGIVSW GDMPCGSKEK PGVYTDVCTH IRWIQNIIRN

K
Length:251
Mass (Da):28,014
Last modified:June 1, 1998 - v1
Checksum:iE21967EF06CEBBF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07003236 Genomic DNA No translation available.
AF016269 mRNA Translation: AAC02300.1
CH473979 Genomic DNA Translation: EDM07531.1
CH473979 Genomic DNA Translation: EDM07532.1
RefSeqiNP_062048.1, NM_019175.1
XP_006229044.1, XM_006228982.3
UniGeneiRn.10732

Genome annotation databases

EnsembliENSRNOT00000065876; ENSRNOP00000060676; ENSRNOG00000031927
GeneIDi29245
KEGGirno:29245
UCSCiRGD:3419 rat

Similar proteinsi

Entry informationi

Entry nameiO54854_RAT
AccessioniPrimary (citable) accession number: O54854
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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