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O54845 (O54845_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Hnf4a MGI 109128
Synonyms:Hnf4 MGI 109128, HNF4alpha EMBL AAC02906.1
OrganismMus musculus (Mouse) EMBL AAC02906.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length100 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains nuclear receptor DNA-binding domain. SAAS SAAS001628

Ontologies

Keywords
   Biological processTranscription
Transcription regulation SAAS SAAS001628
   Cellular componentNucleus SAAS SAAS001628
   DomainZinc-finger SAAS SAAS001628
   LigandDNA-binding SAAS SAAS001628
Metal-binding
Zinc
Gene Ontology (GO)
   Biological_processSMAD protein signal transduction

Inferred from direct assay PubMed 9420335. Source: MGI

lipid metabolic process

Inferred from mutant phenotype PubMed 16498401. Source: MGI

positive regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 10859308PubMed 15581617PubMed 16527247PubMed 17636037. Source: MGI

positive regulation of transcription, DNA-templated

Inferred from direct assay PubMed 9408084Ref.1. Source: MGI

regulation of gastrulation

Inferred from mutant phenotype PubMed 7958910. Source: MGI

regulation of transcription, DNA-templated

Inferred from mutant phenotype PubMed 9053305. Source: MGI

sex differentiation

Inferred from mutant phenotype PubMed 17412818. Source: MGI

signal transduction involved in regulation of gene expression

Inferred from direct assay PubMed 18462699. Source: MGI

transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 10859308. Source: GOC

   Cellular_componentnucleus

Inferred from direct assay PubMed 15767668PubMed 16537911PubMed 17021047PubMed 8306889PubMed 9408084Ref.1. Source: MGI

   Molecular_functionDNA binding

Inferred from direct assay PubMed 15014077PubMed 15581617PubMed 16912278. Source: MGI

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

Inferred from direct assay PubMed 10859308. Source: MGI

sequence-specific DNA binding

Inferred from direct assay PubMed 8306889. Source: MGI

sequence-specific DNA binding transcription factor activity

Inferred from direct assay PubMed 16498401. Source: MGI

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue1001 EMBL AAC02906.1

Sequences

Sequence LengthMass (Da)Tools
O54845 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: F70CC0C1E8D3C7E3

FASTA10010,964
        10         20         30         40         50         60 
MVSVNAPLGA PVASPYDTSP SEGANLNSSN SLGVSALCAI CGDRATAKHY GASSCDGCKG 

        70         80         90        100 
FFRRSVRKNH MYSCRFSRQC VVDKDKRNQC RYCRLKKCFR 

« Hide

References

[1]"An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell types."
Nakhei H., Lingott A., Lemm I., Ryffel G.U.
Nucleic Acids Res. 26:497-504(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF015275 mRNA. Translation: AAC02906.1.
UniGeneMm.202383.

3D structure databases

ProteinModelPortalO54845.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:109128. Hnf4a.

Phylogenomic databases

HOVERGENHBG082808.

Gene expression databases

GenevestigatorO54845.

Family and domain databases

Gene3D3.30.50.10. 1 hit.
InterProIPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSPR00047. STROIDFINGER.
SMARTSM00399. ZnF_C4. 1 hit.
[Graphical view]
PROSITEPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSHNF4A. mouse.
SOURCESearch...

Entry information

Entry nameO54845_MOUSE
AccessionPrimary (citable) accession number: O54845
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: April 16, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)