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Protein
Submitted name:

Clavulanate-9-aldehyde reducatase

Gene

car

Organism
Streptomyces clavuligerus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Clavulanate-9-aldehyde reducataseImported
Gene namesi
Name:carImported
OrganismiStreptomyces clavuligerusImported
Taxonomic identifieri1901 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Interactioni

Protein-protein interaction databases

STRINGi443255.SclaA2_010100020093.

Structurei

3D structure databases

ProteinModelPortaliO54197.
SMRiO54197. Positions 2-247.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QTW. Bacteria.
COG4221. LUCA.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

O54197-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSALQGKVA LITGRELGHR RATARALAPE GAAVAIAARR VEKLRALGDE
60 70 80 90 100
LTAAGAKVHV LELDVADRQG VDAAVASTVE ALGGLDILVN NAGIMLLGPV
110 120 130 140 150
EDADTTDWTR MIDTNLLGLM YMTRAALPHL LRSKGTVVQM SSIAGRVTVR
160 170 180 190 200
NAAVYQATKF GVNAFSETVR QEVTERGVRV VVIEPGTTDT ELRGHITHTA
210 220 230 240
TKEMYEQRIS QIRKLQAQDI AEAVRYAVTA PHHATVHEIF IRPTDQV
Length:247
Mass (Da):26,628
Last modified:June 1, 1998 - v1
Checksum:i251C1E2FC6E75619
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ000671 Genomic DNA. Translation: CAA04227.1.

Genome annotation databases

KEGGiag:CAA04227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ000671 Genomic DNA. Translation: CAA04227.1.

3D structure databases

ProteinModelPortaliO54197.
SMRiO54197. Positions 2-247.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi443255.SclaA2_010100020093.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGiag:CAA04227.

Phylogenomic databases

eggNOGiENOG4107QTW. Bacteria.
COG4221. LUCA.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene."
    Perez-Redondo R., Rodriguez-Garcia A., Martin J.F., Liras P.
    Gene 211:311-321(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 27064Imported.

Entry informationi

Entry nameiO54197_STRCL
AccessioniPrimary (citable) accession number: O54197
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: May 11, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.