Reviewed, UniProtKB/Swiss-Prot O54161 (ABFB_STRCO)

Names and origin

Protein names

Recommended name:
    Alpha-L-arabinofuranosidase
      Short name=Arabinosidase
    EC=3.2.1.55

Gene names

Name:	abfB
Ordered Locus Names:	SCO5932
ORF Names:	SC7H1.02

Organism

Streptomyces coelicolor [Complete proteome] [HAMAP]

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted.
Sequence similarities	Belongs to the glycosyl hydrolase 62 family. Contains 1 ricin B-type lectin domain.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Ligand	Lectin
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose metabolic process Inferred from electronic annotation. Source: InterPro xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	alpha-N-arabinofuranosidase activity Inferred from electronic annotation. Source: EC sugar binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 37	37	Potential
	Chain	38 – 475	438	Alpha-L-arabinofuranosidase		PRO_0000008036
Regions
	Domain	39 – 166	128	Ricin B-type lectin

Sequences

	Sequence		Length	Mass (Da)
	O54161-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 47E707FE543CA60D	FASTA	475	50,046
	10 20 30 40 50 60 MHRGSLSRGH TSAVLAAVVA ALAALAALLV ATTPAQAAGS GALRGAGSNR CLDVLGGSQD 70 80 90 100 110 120 DGALLQLYDC WGGTNQQWTS TDTGRLTVYG DKCLDVPGHA TAPGTRVQIW SCSGGANQQW 130 140 150 160 170 180 RVNSDGTVVG VESGLCLEAA GAGTANGTAV QLWTCNGGGN QKWTGLTGTP PTDGTCALPS 190 200 210 220 230 240 TYRWSSTGVL AQPKSGWVAL KDFTTVTHNG RHLVYGSTSS GSSYGSMVFS PFTNWSDMAS 250 260 270 280 290 300 AGQNAMNQAA VAPTLFYFAP KNIWVLAYQW GSWPFIYRTS SDPTDPNGWS APQPLFTGSI 310 320 330 340 350 360 SGSDTGPIDQ TLIADGQNMY LFFAGDNGKI YRASMPIGNF PGNFGSSYTT IMSDTKANLF 370 380 390 400 410 420 EGVQVYKVQG QNQYLMIVEA MGANGRYFRS FTASSLSGSW TPQAASEGNP FAGKANSGAT 430 440 450 460 470 WTNDISHGDL VRDNPDQTMT VDPCNLQFLY QGKSPNAGGD YNSLPWRPGV LTLRR

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL939125 Genomic DNA. Translation: CAA16189.1.
PIR	T35697.
RefSeq	NP_630049.1.
3D structure databases
HSSP	HSSP built from PDB template 1KNL based on UniProtKB P26514.
ModBase	Search...
Protein family/group databases
CAZy	CBM13. Carbohydrate-Binding Module Family 13. GH62. Glycoside Hydrolase Family 62.
Genome annotation databases
GeneID	1101374.
GenomeReviews	Gene locus SCO5932 in contig AL645882_GR.
KEGG	sco:SCO5932.
NMPDR	fig|100226.1.peg.5879.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O54161.
OMA	O54161. GRYFRSF.
Enzyme and pathway databases
BioCyc	SCOE100226:SCO5932-MON.
BRENDA	3.2.1.55. 1084.
Family and domain databases
InterPro	IPR005193. GH62_arabinosidase. IPR000772. Ricin_B_lectin. [Graphical view]
Pfam	PF03664. Glyco_hydro_62. 1 hit. PF00652. Ricin_B_lectin. 1 hit. [Graphical view]
SMART	SM00458. RICIN. 1 hit. [Graphical view]
PROSITE	PS50231. RICIN_B_LECTIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABFB_STRCO

Accession

Primary (citable) accession number: O54161

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	June 1, 1998
Last modified:	June 16, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)