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Protein

Thioredoxin reductase

Gene

trxB

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thioredoxin + NADP+ = thioredoxin disulfide + NADPH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
LigandFADUniRule annotation, Flavoprotein, NADPUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin reductaseUniRule annotation (EC:1.8.1.9UniRule annotation)
Gene namesi
Name:trxBImported
ORF Names:BN1321_180007Imported, BTN44_08705Imported, EP54_02830Imported, EQ90_03820Imported, HMPREF3211_01109Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000070177 Componenti: Unassembled WGS sequence
  • UP000039437 Componenti: Unassembled WGS sequence
  • UP000236484 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 293FAD/NAD-binding_domInterPro annotationAdd BLAST288

Sequence similaritiesi

Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3M Bacteria
COG0492 LUCA
KOiK00384

Family and domain databases

Gene3Di3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR008255 Pyr_nucl-diS_OxRdtase_2_AS
IPR000103 Pyridine_nuc-diS_OxRdtase_2
IPR005982 Thioredox_Rdtase
PfamiView protein in Pfam
PF07992 Pyr_redox_2, 1 hit
PRINTSiPR00469 PNDRDTASEII
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01292 TRX_reduct, 1 hit
PROSITEiView protein in PROSITE
PS00573 PYRIDINE_REDOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

O54079-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEIDFDIAI IGAGPAGMTA AVYASRANLK TVMIERGIPG GQMANTEEVE
60 70 80 90 100
NFPGFEMITG PDLSTKMFEH AKKFGAVYQY GDIKSVEDKG EYKVINFGNK
110 120 130 140 150
ELTAKAVIIA TGAEYKKIGV PGEQELGGRG VSYCAVCDGA FFKNKRLFVI
160 170 180 190 200
GGGDSAVEEG TFLTKFADKV TIVHRRDELR AQRILQDRAF KNDKIDFIWS
210 220 230 240 250
HTLKSINEKD GKVGSVTLTS TKDGSEETHE ADGVFIYIGM KPLTAPFKDL
260 270 280 290 300
GITNDVGYIV TKDDMTTSVP GIFAAGDVRD KGLRQIVTAT GDGSIAAQSA
310
AEYIEHLNDQ A
Length:311
Mass (Da):33,616
Last modified:October 1, 2003 - v4
Checksum:i1A337DE3736C9265
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei311Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP018629 Genomic DNA Translation: AUS75308.1
AJ223781 Genomic DNA Translation: CAA11546.2
Y18636 Genomic DNA Translation: CAB60740.1
CVOQ01000010 Genomic DNA Translation: CRI08321.1
LALJ01000006 Genomic DNA Translation: KMR37305.1
LALQ01000008 Genomic DNA Translation: KMR58138.1
LRQH01000096 Genomic DNA Translation: KXA36788.1
RefSeqiWP_000134963.1, NZ_PQWV01000003.1

Genome annotation databases

EnsemblBacteriaiAOO97999; AOO97999; FORC27_0761
CRI08321; CRI08321; BN1321_180007
CXE21571; CXE21571; ERS074020_00203
CXL50386; CXL50386; ERS072738_00208
CXS74939; CXS74939; ERS073147_00364
CYC84453; CYC84453; ERS073767_00250
CZQ26001; CZQ26001; ERS1058648_00332
KXA36788; KXA36788; HMPREF3211_01109
OAP80329; OAP80329; A4U86_00395
SCR51762; SCR51762; SAMEA2298760_01966
KEGGisaud:CH52_01945
sauf:X998_0811
PATRICifig|1280.10341.peg.762

Similar proteinsi

Entry informationi

Entry nameiO54079_STAAU
AccessioniPrimary (citable) accession number: O54079
Secondary accession number(s): Q9RL89
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 1, 2003
Last modified: May 23, 2018
This is version 118 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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