Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Thioredoxin reductase

Gene

trxB

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Thioredoxin + NADP+ = thioredoxin disulfide + NADPH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandFADUniRule annotation, Flavoprotein, NADPUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin reductaseUniRule annotation (EC:1.8.1.9UniRule annotation)
Gene namesi
Name:trxBImported
Synonyms:trxB_1Imported, trxB_2Imported
ORF Names:AYM28_04140Imported, AYM37_04140Imported, BN1321_180007Imported, BO217_1188Imported, ERS072738_00208Imported, ERS073071_00665Imported, ERS073583_00469Imported, ERS074020_00203Imported, HMPREF3211_01109Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000071995 Componenti: Unassembled WGS sequence
  • UP000070177 Componenti: Unassembled WGS sequence
  • UP000188815 Componenti: Chromosome
  • UP000187274 Componenti: Unassembled WGS sequence
  • UP000072664 Componenti: Unassembled WGS sequence
  • UP000039437 Componenti: Unassembled WGS sequence
  • UP000187819 Componenti: Unassembled WGS sequence
  • UP000189034 Componenti: Chromosome
  • UP000187748 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 293FAD/NAD-binding_domInterPro annotationAdd BLAST288

Sequence similaritiesi

Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3M. Bacteria.
COG0492. LUCA.
KOiK00384.

Family and domain databases

Gene3Di3.50.50.60. 3 hits.
InterProiView protein in InterPro
IPR023753. FAD/NAD-binding_dom.
IPR008255. Pyr_nucl-diS_OxRdtase_2_AS.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
IPR005982. Thioredox_Rdtase.
PfamiView protein in Pfam
PF07992. Pyr_redox_2. 1 hit.
PRINTSiPR00469. PNDRDTASEII.
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01292. TRX_reduct. 1 hit.
PROSITEiView protein in PROSITE
PS00573. PYRIDINE_REDOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O54079-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEIDFDIAI IGAGPAGMTA AVYASRANLK TVMIERGIPG GQMANTEEVE
60 70 80 90 100
NFPGFEMITG PDLSTKMFEH AKKFGAVYQY GDIKSVEDKG EYKVINFGNK
110 120 130 140 150
ELTAKAVIIA TGAEYKKIGV PGEQELGGRG VSYCAVCDGA FFKNKRLFVI
160 170 180 190 200
GGGDSAVEEG TFLTKFADKV TIVHRRDELR AQRILQDRAF KNDKIDFIWS
210 220 230 240 250
HTLKSINEKD GKVGSVTLTS TKDGSEETHE ADGVFIYIGM KPLTAPFKDL
260 270 280 290 300
GITNDVGYIV TKDDMTTSVP GIFAAGDVRD KGLRQIVTAT GDGSIAAQSA
310
AEYIEHLNDQ A
Length:311
Mass (Da):33,616
Last modified:October 1, 2003 - v4
Checksum:i1A337DE3736C9265
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei311Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP014415 Genomic DNA. Translation: AQR24490.1.
CP014444 Genomic DNA. Translation: AQR51009.1.
AJ223781 Genomic DNA. Translation: CAA11546.2.
Y18636 Genomic DNA. Translation: CAB60740.1.
CVOQ01000010 Genomic DNA. Translation: CRI08321.1.
FFPZ01000001 Genomic DNA. Translation: CXE21571.1.
FGBR01000001 Genomic DNA. Translation: CXL50386.1.
FGJX01000003 Genomic DNA. Translation: CXR51438.1.
FGWW01000002 Genomic DNA. Translation: CYA17896.1.
LRQH01000096 Genomic DNA. Translation: KXA36788.1.
MPPH01000014 Genomic DNA. Translation: OMK04803.1.
RefSeqiWP_000134963.1. NZ_NBZY01000005.1.

Genome annotation databases

EnsemblBacteriaiAOO97999; AOO97999; FORC27_0761.
CRI08321; CRI08321; BN1321_180007.
CXE21571; CXE21571; ERS074020_00203.
CXL50386; CXL50386; ERS072738_00208.
CXS74939; CXS74939; ERS073147_00364.
CYC84453; CYC84453; ERS073767_00250.
CZQ26001; CZQ26001; ERS1058648_00332.
KXA36788; KXA36788; HMPREF3211_01109.
OAP80329; OAP80329; A4U86_00395.
SCR51762; SCR51762; SAMEA2298760_01966.
KEGGisaud:CH52_01945.
sauf:X998_0811.
PATRICifig|1280.10341.peg.762.

Similar proteinsi

Entry informationi

Entry nameiO54079_STAAU
AccessioniPrimary (citable) accession number: O54079
Secondary accession number(s): Q9RL89
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 1, 2003
Last modified: August 30, 2017
This is version 109 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported