UniProtKB - O54079 (O54079_STAAU)
(max 400 entries)x
Your basket is currently empty. i
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
Protein
Thioredoxin reductase
Gene
trxB
Organism
Staphylococcus aureus
Status
Functioni
Catalytic activityi
Thioredoxin + NADP+ = thioredoxin disulfide + NADPH.UniRule annotation
Cofactori
FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation
GO - Molecular functioni
- thioredoxin-disulfide reductase activity Source: UniProtKB-EC
GO - Biological processi
- removal of superoxide radicals Source: InterPro
Keywordsi
Molecular function | OxidoreductaseUniRule annotationSAAS annotationImported |
Ligand | FADUniRule annotation, Flavoprotein, NADPUniRule annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:trxBImported Synonyms:trxB_1Imported ORF Names:B9Z08_03180Imported, BN1321_180007Imported, EP54_02830Imported, EQ90_03820Imported, ERS072738_00208Imported, HMPREF3211_01109Imported |
Organismi | Staphylococcus aureusImported |
Taxonomic identifieri | 1280 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus |
Proteomesi |
|
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 293 | FAD/NAD-binding_domInterPro annotationAdd BLAST | 288 |
Sequence similaritiesi
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation
Keywords - Domaini
Redox-active centerUniRule annotationPhylogenomic databases
eggNOGi | ENOG4105C3M. Bacteria. COG0492. LUCA. |
KOi | K00384. |
Family and domain databases
Gene3Di | 3.50.50.60. 3 hits. |
InterProi | View protein in InterPro IPR036188. FAD/NAD-bd_sf. IPR023753. FAD/NAD-binding_dom. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. |
Pfami | View protein in Pfam PF07992. Pyr_redox_2. 1 hit. |
PRINTSi | PR00469. PNDRDTASEII. |
SUPFAMi | SSF51905. SSF51905. 1 hit. |
TIGRFAMsi | TIGR01292. TRX_reduct. 1 hit. |
PROSITEi | View protein in PROSITE PS00573. PYRIDINE_REDOX_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
O54079-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTEIDFDIAI IGAGPAGMTA AVYASRANLK TVMIERGIPG GQMANTEEVE
60 70 80 90 100
NFPGFEMITG PDLSTKMFEH AKKFGAVYQY GDIKSVEDKG EYKVINFGNK
110 120 130 140 150
ELTAKAVIIA TGAEYKKIGV PGEQELGGRG VSYCAVCDGA FFKNKRLFVI
160 170 180 190 200
GGGDSAVEEG TFLTKFADKV TIVHRRDELR AQRILQDRAF KNDKIDFIWS
210 220 230 240 250
HTLKSINEKD GKVGSVTLTS TKDGSEETHE ADGVFIYIGM KPLTAPFKDL
260 270 280 290 300
GITNDVGYIV TKDDMTTSVP GIFAAGDVRD KGLRQIVTAT GDGSIAAQSA
310
AEYIEHLNDQ A
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 311 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ223781 Genomic DNA. Translation: CAA11546.2. Y18636 Genomic DNA. Translation: CAB60740.1. CVOQ01000010 Genomic DNA. Translation: CRI08321.1. FGBR01000001 Genomic DNA. Translation: CXL50386.1. LALJ01000006 Genomic DNA. Translation: KMR37305.1. LALQ01000008 Genomic DNA. Translation: KMR58138.1. LRQH01000096 Genomic DNA. Translation: KXA36788.1. NESW01000002 Genomic DNA. Translation: PHZ48641.1. |
RefSeqi | WP_000134963.1. NZ_PJLW01000054.1. |
Genome annotation databases
EnsemblBacteriai | AOO97999; AOO97999; FORC27_0761. CRI08321; CRI08321; BN1321_180007. CXE21571; CXE21571; ERS074020_00203. CXL50386; CXL50386; ERS072738_00208. CXS74939; CXS74939; ERS073147_00364. CYC84453; CYC84453; ERS073767_00250. CZQ26001; CZQ26001; ERS1058648_00332. KXA36788; KXA36788; HMPREF3211_01109. OAP80329; OAP80329; A4U86_00395. SCR51762; SCR51762; SAMEA2298760_01966. |
KEGGi | saud:CH52_01945. sauf:X998_0811. |
PATRICi | fig|1280.10341.peg.762. |
Similar proteinsi
Entry informationi
Entry namei | O54079_STAAU | |
Accessioni | O54079Primary (citable) accession number: O54079 Secondary accession number(s): Q9RL89 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 1998 |
Last sequence update: | October 1, 2003 | |
Last modified: | March 28, 2018 | |
This is version 116 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |