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Reviewed, UniProtKB/Swiss-Prot O54068 (UDG_RHIME)

Last modified November 25, 2008. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    UDP-glucose 6-dehydrogenase
      Short name=UDP-Glc dehydrogenase
      Short name=UDP-GlcDH
      Short name=UDPGDH
    EC=1.1.1.22
Gene names
Name: rkpK
Ordered Locus Names: R01082
ORF Names: SMc02641
OrganismRhizobium meliloti (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier382 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Ontologies

Keywords

   Biological processCapsule biogenesis/degradation
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionNAD binding

Inferred from electronic annotation. Source: InterPro

UDP-glucose 6-dehydrogenase activity

Inferred from electronic annotation. Source: EC

electron carrier activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 437437UDP-glucose 6-dehydrogenase
PRO_0000074050

Sites

Active site2651 By similarity

Experimental info

Sequence conflict1091A → S in CAA10918. Ref.1
Sequence conflict1421A → V in CAA10918. Ref.1
Sequence conflict3181I → Y in CAA10918. Ref.1
Sequence conflict3351S → T in CAA10918. Ref.1

Sequences

Sequence LengthMass (Da)Tools
O54068-1 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: 2D458D39A1D8EEC1

FASTA43747,122
        10         20         30         40         50         60 
MKITMIGAGY VGLVSGVCFA DFGHDVVCVD KDEGKISALK KGQIPIFEPG LDHLVASNVA 

        70         80         90        100        110        120 
SGRLNFTDDL KTAVAASDVV FIAVGTPSRR GDGHADLSYV YAAAREIAAN LQGFTVVVTK 

       130        140        150        160        170        180 
STVPVGTGDE VERIIRETNP AADVTVVSNP EFLREGAAIE DFKRPDRIVI GVDGSDGRAR 

       190        200        210        220        230        240 
EVMTEVYRPL YLNQSPLVFT TRRTSELIKY AGNAFLAMKI TFINEIADLC EKVGANVQDV 

       250        260        270        280        290        300 
ARGIGLDGRI GSKFLHAGPG YGGSCFPKDT LALVKTAQDH DTPVRLVETT VAVNDNRKRA 

       310        320        330        340        350        360 
MGRKVIAAAG GDIRGSKIAV LGLTFKPNTD DMRDSPAIAV VQALQDAGAR VTGYDPEGME 

       370        380        390        400        410        420 
NARKLIEGLD CARDPYEAAA EADALVIITE WNEFRALDFD RLKSTMKTPL LVDLRNIYRK 

       430 
DEVAKHGFRY ASIGRPD 

« Hide

References

« Hide 'large scale' references
[1]"Novel rkp gene clusters of Sinorhizobium meliloti involved in capsular polysaccharide production and invasion of the symbiotic nodule: the rkpK gene encodes a UDP-glucose dehydrogenase."
Kereszt A., Kiss E., Reuhs B.L., Carlson R.W., Kondorosi A., Putnoky P.
J. Bacteriol. 180:5426-5431(1998) [PubMed: 9765575] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 41.
[2]"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021."
Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. expand/collapse author list , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.
Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed: 11481430] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1021.

Cross-references

Sequence databases

AJ222661 Genomic DNA. Translation: CAA10918.1.
AL591688 Genomic DNA. Translation: CAC45661.1.
PIRT46573.
RefSeqNP_385188.1.

3D structure databases

HSSPHSSP built from PDB template 1MV8 based on UniProtKB P11759.
ModBaseSearch...

Genome annotation databases

GeneID1232726.
GenomeReviewsGene locus R01082 in contig AL591688_GR.
KEGGsme:SMc02641.
NMPDRfig|266834.1.peg.2376.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMO54068.

Enzyme and pathway databases

BioCycSMEL266834:SMC02641-MON.

Family and domain databases

InterProIPR013328. DHase_multihelical.
IPR016040. NAD(P)-bd.
IPR017476. Nucleotide_sugar_DH.
IPR001100. Pyr_nuc-diS_OxRdtase.
IPR014027. UDP-Glc/GDP-Man_DHase_C.
IPR014026. UDP-Glc/GDP-Man_DHase_dimer.
IPR014028. UDP-Glc/GDP-Man_DHase_dimer-bd.
IPR001732. UDP-Glc/GDP-Man_DHase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
G3DSA:3.40.50.1870. UDP-Glc/GDP-Man_DH_C. 1 hit.
PANTHERPTHR11374. UDPG_MGDP_DH_Creg. 1 hit.
PfamPF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view]
PRINTSPR00411. PNDRDTASEI.
ProtoNetSearch...

Entry information

Entry nameUDG_RHIME
AccessionPrimary (citable) accession number: O54068
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: November 25, 2008
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents