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Protein
Submitted name:

ArsR family transcriptional regulator

Gene

Rv1674c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-5864-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ArsR family transcriptional regulatorImported
Submitted name:
Probable transcriptional regulatory proteinImported
Gene namesi
Ordered Locus Names:Rv1674cImported
ORF Names:LH57_09125Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1674c.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1674c.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 98HTH arsR-type DNA-bindingInterPro annotationAdd BLAST95
Domaini128 – 217RhodaneseInterPro annotationAdd BLAST90

Sequence similaritiesi

Contains 1 HTH arsR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UM0. Bacteria.
COG0607. LUCA.
COG0640. LUCA.
HOGENOMiHOG000005258.
OMAiAYCRGRY.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.250.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR001763. Rhodanese-like_dom.
IPR001307. Thiosulphate_STrfase_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01022. HTH_5. 1 hit.
PF00581. Rhodanese. 1 hit.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
SM00450. RHOD. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF52821. SSF52821. 1 hit.
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
PS00380. RHODANESE_1. 1 hit.
PS50206. RHODANESE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O53921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGAKKLIFE QFALVGQALS SGHRLELLDL LVQGERSVDA LARASGLTFA
60 70 80 90 100
NASQHLLQLR RAGLVTSRRD GKRVIYALSD PQVWDVVRAV RAVAERNLAS
110 120 130 140 150
VGSLVRQYYT DRDSLEPISR DELQARVAAG SVLVLDVRPA MEYAAGHLPG
160 170 180 190 200
AVSIPLDELA ERLDELPSGI DIVACCRGPY CVYAYDALEL LRPNGFSARR
210
LDGGFSEWLA ADLPVVRT
Length:218
Mass (Da):23,759
Last modified:June 1, 1998 - v1
Checksum:iE62A3A402C405DD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14425.1.
AL123456 Genomic DNA. Translation: CCP44439.1.
RefSeqiNP_216190.1. NC_000962.3.
WP_003408266.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR14425; AIR14425; LH57_09125.
CCP44439; CCP44439; Rv1674c.
GeneIDi885696.
KEGGimtu:Rv1674c.
mtv:RVBD_1674c.
PATRICi18125520. VBIMycTub22151_1874.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14425.1.
AL123456 Genomic DNA. Translation: CCP44439.1.
RefSeqiNP_216190.1. NC_000962.3.
WP_003408266.1. NZ_KK339370.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1674c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR14425; AIR14425; LH57_09125.
CCP44439; CCP44439; Rv1674c.
GeneIDi885696.
KEGGimtu:Rv1674c.
mtv:RVBD_1674c.
PATRICi18125520. VBIMycTub22151_1874.

Organism-specific databases

TubercuListiRv1674c.

Phylogenomic databases

eggNOGiENOG4108UM0. Bacteria.
COG0607. LUCA.
COG0640. LUCA.
HOGENOMiHOG000005258.
OMAiAYCRGRY.

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-5864-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.250.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR001763. Rhodanese-like_dom.
IPR001307. Thiosulphate_STrfase_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01022. HTH_5. 1 hit.
PF00581. Rhodanese. 1 hit.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
SM00450. RHOD. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF52821. SSF52821. 1 hit.
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
PS00380. RHODANESE_1. 1 hit.
PS50206. RHODANESE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO53921_MYCTU
AccessioniPrimary (citable) accession number: O53921
Secondary accession number(s): I6XC39, Q7D865
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.