Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

DNA helicase Ercc3

Gene

ercc3

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HelicaseImported, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMTBRV:RV0861C-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA helicase Ercc3Imported
Gene namesi
Name:ercc3Imported
Ordered Locus Names:Rv0861cImported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: MTBBASE
  • plasma membrane Source: MTBBASE
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO53873.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0861c.

Structurei

3D structure databases

ProteinModelPortaliO53873.
SMRiO53873. Positions 158-529.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini183 – 337155Helicase ATP-bindingInterPro annotationAdd
BLAST
Domaini392 – 538147Helicase C-terminalInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105DYP. Bacteria.
COG1061. LUCA.
HOGENOMiHOG000239540.
KOiK10843.
OMAiGSFGSRQ.
PhylomeDBiO53873.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR032438. ERCC3_RAD25_C.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR032830. XPB/Ssl2_N.
[Graphical view]
PfamiPF16203. ERCC3_RAD25_C. 1 hit.
PF13625. Helicase_C_3. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O53873-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSDKTVLLE VDHELAGAAR AAIAPFAELE RAPEHVHTYR ITPLALWNAR
60 70 80 90 100
AAGHDAEQVV DALVSYSRYA VPQPLLVDIV DTMARYGRLQ LVKNPAHGLT
110 120 130 140 150
LVSLDRAVLE EVLRNKKIAP MLGARIDDDT VVVHPSERGR VKQLLLKIGW
160 170 180 190 200
PAEDLAGYVD GEAHPISLHQ EGWQLRDYQR LAADSFWAGG SGVVVLPCGA
210 220 230 240 250
GKTLVGAAAM AKAGATTLIL VTNIVAARQW KRELVARTSL TENEIGEFSG
260 270 280 290 300
ERKEIRPVTI STYQMITRRT KGEYRHLELF DSRDWGLIIY DEVHLLPAPV
310 320 330 340 350
FRMTADLQSK RRLGLTATLI REDGREGDVF SLIGPKRYDA PWKDIEAQGW
360 370 380 390 400
IAPAECVEVR VTMTDSERMM YATAEPEERY RICSTVHTKI AVVKSILAKH
410 420 430 440 450
PDEQTLVIGA YLDQLDELGA ELGAPVIQGS TRTSEREALF DAFRRGEVAT
460 470 480 490 500
LVVSKVANFS IDLPEAAVAV QVSGTFGSRQ EEAQRLGRIL RPKADGGGAI
510 520 530 540
FYSVVARDSL DAEYAAHRQR FLAEQGYGYI IRDADDLLGP AI
Length:542
Mass (Da):59,804
Last modified:June 1, 1998 - v1
Checksum:iFC7C1FBA9B34B0B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43609.1.
RefSeqiNP_215376.3. NC_000962.3.
WP_003404428.1. NC_000962.3.

Genome annotation databases

EnsemblBacteriaiCCP43609; CCP43609; Rv0861c.
GeneIDi885425.
KEGGimtu:Rv0861c.
mtv:RVBD_0861c.
PATRICi18150439. VBIMycTub87468_0962.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43609.1.
RefSeqiNP_215376.3. NC_000962.3.
WP_003404428.1. NC_000962.3.

3D structure databases

ProteinModelPortaliO53873.
SMRiO53873. Positions 158-529.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0861c.

Proteomic databases

PaxDbiO53873.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCP43609; CCP43609; Rv0861c.
GeneIDi885425.
KEGGimtu:Rv0861c.
mtv:RVBD_0861c.
PATRICi18150439. VBIMycTub87468_0962.

Phylogenomic databases

eggNOGiENOG4105DYP. Bacteria.
COG1061. LUCA.
HOGENOMiHOG000239540.
KOiK10843.
OMAiGSFGSRQ.
PhylomeDBiO53873.

Enzyme and pathway databases

BioCyciMTBRV:RV0861C-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR032438. ERCC3_RAD25_C.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR032830. XPB/Ssl2_N.
[Graphical view]
PfamiPF16203. ERCC3_RAD25_C. 1 hit.
PF13625. Helicase_C_3. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO53873_MYCTU
AccessioniPrimary (citable) accession number: O53873
Secondary accession number(s): F2GIZ2, I6WZM2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: September 7, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.