O53815 (O53815_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acyl-CoA dehydrogenase EMBL AAK45017.1

Submitted name:
PROBABLE ACYL-CoA DEHYDROGENASE FADE9 EMBL CAA17519.1
EC=1.3.99.- EMBL CAA17519.1

Gene names

Name:	fadE9 EMBL CAA17519.1
Ordered Locus Names:	MT0776, Rv0752c

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the acyl-CoA dehydrogenase family. RuleBase RU004309

Ontologies

Keywords
Ligand	FAD RuleBase RU003714 Flavoprotein RuleBase RU003714
Molecular function	Oxidoreductase RuleBase RU003714 EMBL CAA17519.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	acyl-CoA dehydrogenase activity Inferred from electronic annotation. Source: InterPro flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O53815 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 575EC02696ADED2F	FASTA	390	41,451
	10 20 30 40 50 60 MFVLNDDERV IVETAAAFAG KRLAPHALEW DAAKHFPVDV LREAAELGMA AIYCRDDVGG 70 80 90 100 110 120 SGLRRLDGVR IFEQLAIADP VTAAFLSIHN MCAWMIDSFG TDEQRKDWIP RLATMGVIAS 130 140 150 160 170 180 YCLTEPGAGS DAGALSTRAV RHGSGKGGDY VLDGVKQFIS GAAASDVYVV MARTGAEGPR 190 200 210 220 230 240 GVSAFIVEKG TPGLSFGAPE AKMGWHAQPT AQVVLDGVRV PAEAMLGGAD GEGAGFGIAM 250 260 270 280 290 300 SGLNGGRLNI AACSLGGAQA AFDKAGAYVR DRQAFGGSLL DEPTVRFTLA DMATGLQTSR 310 320 330 340 350 360 MLLWRAASAL DDDDADKVEL CAMAKRYVTD TCFEVADQAL QLHGGYGYLR EYGLEKIVRD 370 380 390 LRVHRILEGT NEIMRLVIGR AEAARFRATV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R. Jr, Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
[3]	"Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv." Camus J.-C., Pryor M.J., Medigue C., Cole S.T. Microbiology 148:2967-2973(2002) [PubMed: 12368430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: H37Rv.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000516 Genomic DNA. Translation: AAK45017.1. BX842574 Genomic DNA. Translation: CAA17519.1.
PIR	C70825.
RefSeq	NP_215266.1. NC_000962.2. NP_335203.1. NC_002755.2.
3D structure databases
HSSP	HSSP built from PDB template 1BUC based on UniProtKB Q06319.
ProteinModelPortal	O53815.
SMR	O53815. Positions 2-382.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000000408; EBMYCP00000000408; EBMYCG00000000408. EBMYCT00000071753; EBMYCP00000069812; EBMYCG00000071748.
GeneID	888684. 926077.
GenomeReviews	Gene locus MT0776 in contig AE000516_GR. Gene locus Rv0752c in contig AL123456_GR.
KEGG	mtc:MT0776. mtu:Rv0752c.
PATRIC	18123448. VBIMycTub22151_0853.
TIGR	MT0776.
Organism-specific databases
TubercuList	Rv0752c.
Phylogenomic databases
GeneTree	EBGT00050000015288.
HOGENOM	HBG699365.
OMA	PLANTQY.
PhylomeDB	O53815.
ProtClustDB	CLSK790713.
Family and domain databases
InterPro	IPR006089. Acyl-CoA_DH_CS. IPR006092. Acyl-CoA_DH_N. IPR006090. Acyl-CoA_Oxase/DH_1. IPR006091. Acyl-CoA_Oxase/DH_cen-dom. IPR009075. AcylCo_DH/oxidase_C. IPR013786. AcylCoA_DH/ox_N. IPR009100. AcylCoA_DH/oxidase. [Graphical view]
Gene3D	G3DSA:2.40.110.10. Acyl_CoA_DH/ox_M. 1 hit. G3DSA:1.10.540.10. AcylCoA_DH/ox_N. 1 hit. G3DSA:1.20.140.10. AcylCoA_DH_1/2_C. 1 hit.
KO	K00257.
Pfam	PF00441. Acyl-CoA_dh_1. 1 hit. PF02770. Acyl-CoA_dh_M. 1 hit. PF02771. Acyl-CoA_dh_N. 1 hit. [Graphical view]
SUPFAM	SSF56645. AcylCoA_dehyd_NM. 1 hit. SSF47203. AcylCoADH_C_like. 1 hit.
PROSITE	PS00072. ACYL_COA_DH_1. 1 hit. PS00073. ACYL_COA_DH_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O53815_MYCTU

Accession

Primary (citable) accession number: O53815
Secondary accession number(s): Q7D9C2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	December 14, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)