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Protein
Submitted name:

Probable dehydrogenase/reductase

Gene

Rv0439c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-4564-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Probable dehydrogenase/reductaseImported
Submitted name:
Short-chain dehydrogenaseImported
Gene namesi
Ordered Locus Names:Rv0439cImported
ORF Names:LH57_02345Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: MTBBASE
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiO53726.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0439c.

Structurei

3D structure databases

ProteinModelPortaliO53726.
SMRiO53726.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4106YMM. Bacteria.
COG1028. LUCA.
OMAiAHIVGKM.
PhylomeDBiO53726.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

O53726-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTANDNKTRK WSAADVPDQS GRVVVVTGAN TGIGYHTAAV FADRGAHVVL
60 70 80 90 100
AVRNLEKGNA ARARIMAARP GAHVTLQQLD LCSLDSVRAA ADALRTAYPR
110 120 130 140 150
IDVLINNAGV MWTPKQVTKD GFELQFGTNH LGHFALTGLV LDHMLPVPGS
160 170 180 190 200
RVVTVSSQGH RIHAAIHFDD LQWERRYNRV AAYGQAKLAN LLFTYELQRR
210 220 230 240 250
LGEAGKSTIA VAAHPGGSNT ELTRNLPRLI RPVATVLGPL LFQSPEMGAL
260 270 280 290 300
PTLRAATDPT TQGGQYYGPD GFGEQRGHPK VVQSSAQSHD KDLQRRLWTV
310
SEELTGVSFG V
Length:311
Mass (Da):33,650
Last modified:July 5, 2004 - v3
Checksum:i39D021BF6C9E8924
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13160.1.
AL123456 Genomic DNA. Translation: CCP43170.1.
RefSeqiNP_214953.1. NC_000962.3.
WP_003402219.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR13160; AIR13160; LH57_02345.
CCP43170; CCP43170; Rv0439c.
GeneIDi886342.
KEGGimtu:Rv0439c.
mtv:RVBD_0439c.
PATRICi18149462. VBIMycTub87468_0483.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13160.1.
AL123456 Genomic DNA. Translation: CCP43170.1.
RefSeqiNP_214953.1. NC_000962.3.
WP_003402219.1. NZ_KK339370.1.

3D structure databases

ProteinModelPortaliO53726.
SMRiO53726.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0439c.

Proteomic databases

PRIDEiO53726.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR13160; AIR13160; LH57_02345.
CCP43170; CCP43170; Rv0439c.
GeneIDi886342.
KEGGimtu:Rv0439c.
mtv:RVBD_0439c.
PATRICi18149462. VBIMycTub87468_0483.

Phylogenomic databases

eggNOGiENOG4106YMM. Bacteria.
COG1028. LUCA.
OMAiAHIVGKM.
PhylomeDBiO53726.

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-4564-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO53726_MYCTU
AccessioniPrimary (citable) accession number: O53726
Secondary accession number(s): F2GMF6, I6X948, L0T3K3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.