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Protein
Submitted name:

Peptidase

Gene

mycP3

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • growth Source: MTBBASE
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseImported

Enzyme and pathway databases

BioCyciMTBRV:RV0291-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PeptidaseImported
Submitted name:
Probable membrane-anchored mycosin MycP3 (Serine protease) (Subtilisin-like protease) (Subtilase-like) (Mycosin-3)Imported
Gene namesi
Name:mycP3Imported
Ordered Locus Names:Rv0291Imported
ORF Names:LH57_01590Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei431 – 45323HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cell wall Source: MTBBASE
  • extracellular region Source: MTBBASE
  • integral component of plasma membrane Source: MTBBASE
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 461436Sequence analysisPRO_5007921818Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0291.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini86 – 389304Peptidase S8InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG41090GG. Bacteria.
COG1404. LUCA.
HOGENOMiHOG000043842.
KOiK14743.
OMAiITATAHN.

Family and domain databases

Gene3Di3.40.50.200. 1 hit.
InterProiIPR000209. Peptidase_S8/S53_dom.
IPR022398. Peptidase_S8_His-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR023834. T7SS_pept_S8A_mycosin-1.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 2 hits.
PfamiPF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 2 hits.
TIGRFAMsiTIGR03921. T7SS_mycosin. 1 hit.
PROSITEiPS00137. SUBTILASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O53695-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRAAFACLA ATVVVAGWWT PPAWAIGPPV VDAAAQPPSG DPGPVAPMEQ
60 70 80 90 100
RGACSVSGVI PGTDPGVPTP SQTMLNLPAA WQFSRGEGQL VAIIDTGVQP
110 120 130 140 150
GPRLPNVDAG GDFVESTDGL TDCDGHGTLV AGIVAGQPGN DGFSGVAPAA
160 170 180 190 200
RLLSIRAMST KFSPRTSGGD PQLAQATLDV AVLAGAIVHA ADLGAKVINV
210 220 230 240 250
STITCLPADR MVDQAALGAA IRYAAVDKDA VIVAAAGNTG ASGSVSASCD
260 270 280 290 300
SNPLTDLSRP DDPRNWAGVT SVSIPSWWQP YVLSVASLTS AGQPSKFSMP
310 320 330 340 350
GPWVGIAAPG ENIASVSNSG DGALANGLPD AHQKLVALSG TSYAAGYVSG
360 370 380 390 400
VAALVRSRYP GLNATEVVRR LTATAHRGAR ESSNIVGAGN LDAVAALTWQ
410 420 430 440 450
LPAEPGGGAA PAKPVADPPV PAPKDTTPRN VAFAGAAALS VLVGLTAATV
460
AIARRRREPT E
Length:461
Mass (Da):46,127
Last modified:June 1, 1998 - v1
Checksum:i7380B819B9356C2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13014.1.
AL123456 Genomic DNA. Translation: CCP43021.1.
RefSeqiNP_214805.1. NC_000962.3.
WP_003401528.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR13014; AIR13014; LH57_01590.
CCP43021; CCP43021; Rv0291.
GeneIDi886615.
KEGGimtu:Rv0291.
mtv:RVBD_0291.
PATRICi18149140. VBIMycTub87468_0323.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13014.1.
AL123456 Genomic DNA. Translation: CCP43021.1.
RefSeqiNP_214805.1. NC_000962.3.
WP_003401528.1. NZ_KK339370.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0291.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR13014; AIR13014; LH57_01590.
CCP43021; CCP43021; Rv0291.
GeneIDi886615.
KEGGimtu:Rv0291.
mtv:RVBD_0291.
PATRICi18149140. VBIMycTub87468_0323.

Phylogenomic databases

eggNOGiENOG41090GG. Bacteria.
COG1404. LUCA.
HOGENOMiHOG000043842.
KOiK14743.
OMAiITATAHN.

Enzyme and pathway databases

BioCyciMTBRV:RV0291-MONOMER.

Family and domain databases

Gene3Di3.40.50.200. 1 hit.
InterProiIPR000209. Peptidase_S8/S53_dom.
IPR022398. Peptidase_S8_His-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR023834. T7SS_pept_S8A_mycosin-1.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 2 hits.
PfamiPF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 2 hits.
TIGRFAMsiTIGR03921. T7SS_mycosin. 1 hit.
PROSITEiPS00137. SUBTILASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO53695_MYCTU
AccessioniPrimary (citable) accession number: O53695
Secondary accession number(s): F2GM95, I6WY21, L0T376
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.