Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

3-ketoacyl-ACP reductase

Gene

fabG

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16920.
MTBRV:RV3502C-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
3-ketoacyl-ACP reductaseImported (EC:1.1.1.100Imported)
Submitted name:
Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenaseImported
Gene namesi
Name:fabGImported
Ordered Locus Names:Rv3502cImported
ORF Names:LH57_19095Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv3502c.

Structurei

3D structure databases

SMRiO53547. Positions 17-315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107D2P. Bacteria.
ENOG410XQXR. LUCA.
KOiK00059.
OMAiVFVVYGP.
OrthoDBiEOG6N3CR8.
PhylomeDBiO53547.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O53547-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLTESNRSP RTTNTTDLSG KVAVVTGAAA GLGRAEALGL ARLGATVVVN
60 70 80 90 100
DVASALDASD VVDEIGAAAA DAGAKAVAVA GDISQRATAD ELLASAVGLG
110 120 130 140 150
GLDIVVNNAG ITRDRMLFNM SDEEWDAVIA VHLRGHFLLT RNAAAYWRDK
160 170 180 190 200
AKDAEGGSVF GRLVNTSSEA GLVGPVGQAN YAAAKAGITA LTLSAARALG
210 220 230 240 250
RYGVCANVIC PRARTAMTAD VFGAAPDVEA GQIDPLSPQH VVSLVQFLAS
260 270 280 290 300
PAAAEVNGQV FIVYGPQVTL VSPPHMERRF SADGTSWDPT ELTATLRDYF
310
AGRDPEQSFS ATDLMRQ
Length:317
Mass (Da):32,753
Last modified:June 1, 1998 - v1
Checksum:iE215957102FAE9FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR16296.1.
AL123456 Genomic DNA. Translation: CCP46324.1.
RefSeqiNP_218019.1. NC_000962.3.
WP_003418990.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR16296; AIR16296; LH57_19095.
CCP46324; CCP46324; Rv3502c.
GeneIDi887697.
KEGGimtu:Rv3502c.
mtv:RVBD_3502c.
PATRICi18156398. VBIMycTub87468_3909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR16296.1.
AL123456 Genomic DNA. Translation: CCP46324.1.
RefSeqiNP_218019.1. NC_000962.3.
WP_003418990.1. NZ_KK339370.1.

3D structure databases

SMRiO53547. Positions 17-315.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv3502c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR16296; AIR16296; LH57_19095.
CCP46324; CCP46324; Rv3502c.
GeneIDi887697.
KEGGimtu:Rv3502c.
mtv:RVBD_3502c.
PATRICi18156398. VBIMycTub87468_3909.

Phylogenomic databases

eggNOGiENOG4107D2P. Bacteria.
ENOG410XQXR. LUCA.
KOiK00059.
OMAiVFVVYGP.
OrthoDBiEOG6N3CR8.
PhylomeDBiO53547.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16920.
MTBRV:RV3502C-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiO53547_MYCTU
AccessioniPrimary (citable) accession number: O53547
Secondary accession number(s): F2GJ65, I6YGB8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: May 11, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.