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O53516 (O53516_MYCTU) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Ordered Locus Names:Rv2182c EMBL CCP44959.1
ORF Names:P425_02259 EMBL KBJ32512.1, RVBD_2182c EMBL AFN50130.1
OrganismMycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [Reference proteome] [HAMAP] EMBL AFN50130.1
Taxonomic identifier83332 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length247 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Molecular functionAcyltransferase EMBL AFN50130.1
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgrowth

Inferred from mutant phenotype PubMed 12657046. Source: MTBBASE

   Cellular_componentplasma membrane

Inferred from direct assay PubMed 14532352. Source: MTBBASE

   Molecular_functiontransferase activity, transferring acyl groups

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
O53516 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: FB1094228A340BDB

FASTA24726,955
        10         20         30         40         50         60 
MWYYLFKYIF MGPLFTLLGR PKVEGLEYIP SSGPAILASN HLAVADSFYL PLVVRRRIWF 

        70         80         90        100        110        120 
LAKSEYFTGT GLKGWINRWF YSVSGQVPID RTNADSAQGA LQTAVVLLGQ GKLLGMYPEG 

       130        140        150        160        170        180 
TRSPDGRLYK GKTGLARLAL HTGVPVIPVA MIGTNVVNPP GRKMLRFGRV TVRFGKPMDF 

       190        200        210        220        230        240 
SRFEGLAGNH FIERAVTDEV IYELMGLSGQ EYVDIYAASV KDGRNAGGAG ANPNSTDAAR 


IPETAAG 

« Hide

References

« Hide 'large scale' references
[1]"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence."
Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. expand/collapse author list , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G.
Nature 393:537-544(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25618 / H37Rv and H37Rv EMBL CCP44959.1.
[2]"Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv."
Camus J.C., Pryor M.J., Medigue C., Cole S.T.
Microbiology 148:2967-2973(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: H37Rv EMBL CCP44959.1.
[3]"Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry."
Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K., Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R., Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M., Kumar P. expand/collapse author list , Chaerkady R., Ramachandran S., Dash D., Pandey A.
Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[4]"TubercuList--10 years after."
Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
Tuberculosis 91:1-7(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: H37Rv EMBL CCP44959.1.
[5]Lew J.M.
Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: H37Rv EMBL CCP44959.1.
[6]"The Genome Sequence of Mycobacterium tuberculosis H37Rv."
The Broad Institute Genome Sequencing Platform, The Broad Institute Genome Sequencing Center for Infectious Disease
Galagan J., Kreiswirth B., Dobos K., Fortune S., Fitzgerald M., Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M. expand/collapse author list , Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.
Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: H37Rv EMBL AFN50130.1.
[7]"The genome sequence of Mycobacterium tuberculosis H37Rv."
The Broad Institute Genome Sequencing Platform
Galagan J., Kreiswirth B., Dobos K., Fortune S., Fitzgerald M., Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M. expand/collapse author list , Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.
Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25618 / H37Rv.
[8]"The Genome Sequence of Mycobacterium tuberculosis H37Rv."
The Broad Institute Genomics Platform, The Broad Institute Genome Sequencing Center for Infectious Disease
Earl A.M., Kreiswirth B., Gomez J., Victor T., Desjardins C., Abeel T., Young S., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C. expand/collapse author list , Imamovic A., Larimer J., Murphy C., Naylor J., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.
Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: H37Rv EMBL KBJ32512.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003248 Genomic DNA. Translation: AFN50130.1.
AL123456 Genomic DNA. Translation: CCP44959.1.
JLDD01000028 Genomic DNA. Translation: KBJ32512.1.
RefSeqNP_216698.1. NC_000962.3.
YP_006515601.1. NC_018143.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING83332.Rv2182c.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFN50130; AFN50130; RVBD_2182c.
GeneID888625.
KEGGmtu:Rv2182c.
mtv:RVBD_2182c.
PATRIC18126676. VBIMycTub22151_2450.

Phylogenomic databases

KOK00655.
OMAEIMYELM.
OrthoDBEOG6QG8JH.

Family and domain databases

InterProIPR002123. Plipid/glycerol_acylTrfase.
[Graphical view]
PfamPF01553. Acyltransferase. 1 hit.
[Graphical view]
SMARTSM00563. PlsC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameO53516_MYCTU
AccessionPrimary (citable) accession number: O53516
Secondary accession number(s): F2GJY9, I6YCR4, Q7D7E3
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: July 9, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)