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Protein

Ribosome-binding ATPase YchF

Gene

ychF

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 17ATPUniRule annotation6

GO - Molecular functioni

Keywordsi

LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome-binding ATPase YchFUniRule annotation
Gene namesi
Name:ychFUniRule annotation
Ordered Locus Names:Rv1112Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1112.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • plasma membrane Source: MTBBASE

PTM / Processingi

Proteomic databases

PaxDbiO53459.
PRIDEiO53459.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1112.

Structurei

3D structure databases

ProteinModelPortaliO53459.
SMRiO53459.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 250OBG-type GInterPro annotationAdd BLAST248

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3G. Bacteria.
COG0012. LUCA.
HOGENOMiHOG000087629.
KOiK06942.
OMAiHKDFEKG.
PhylomeDBiO53459.

Family and domain databases

Gene3Di1.10.150.300. 1 hit.
3.10.20.30. 1 hit.
HAMAPiMF_00944. YchF_OLA1_ATPase. 1 hit.
InterProiView protein in InterPro
IPR004396. ATPase_YchF/OLA1.
IPR012675. Beta-grasp_dom.
IPR013029. DUF933.
IPR031167. G_OBG.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR012676. TGS-like.
IPR023192. TGS-like_dom.
PfamiView protein in Pfam
PF01926. MMR_HSR1. 1 hit.
PF06071. YchF-GTPase_C. 1 hit.
PIRSFiPIRSF006641. CHP00092. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00092. TIGR00092. 1 hit.
PROSITEiView protein in PROSITE
PS51710. G_OBG. 1 hit.

Sequencei

Sequence statusi: Complete.

O53459-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSLGIVGL PNVGKSTLFN ALTRNNVVAA NYPFATIEPN EGVVSLPDPR
60 70 80 90 100
LDKLAELFGS QRVVPAPVTF VDIAGLVKGA SEGAGLGNKF LAHIRECDAI
110 120 130 140 150
CQVVRVFVDD DVTHVTGRVD PQSDIEVVET ELILADLQTL ERATGRLEKE
160 170 180 190 200
ARTNKARKPV YDAALRAQQV LDAGKTLFAA GVDAAALREL NLLTTKPFLY
210 220 230 240 250
VFNADEAVLT DPARVGELRA LVAPADAVFL DAAIESELTE LDDESAAELL
260 270 280 290 300
ESIGQSERGL DALARAGFHT LKLQTFLTAG PKEARAWTIH QGDTAPKAAG
310 320 330 340 350
VIHSDFEKGF IKAEIVSYDD LVAAGSMAAA KAAGKVRIEG KDYVMADGDV

VEFRFNV
Length:357
Mass (Da):38,097
Last modified:August 1, 1998 - v2
Checksum:iC70A5951D18114D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43865.1.
RefSeqiNP_215628.1. NC_000962.3.
WP_003898732.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiCCP43865; CCP43865; Rv1112.
GeneIDi887151.
KEGGimtu:Rv1112.
mtv:RVBD_1112.
PATRICifig|83332.111.peg.1240.

Similar proteinsi

Entry informationi

Entry nameiO53459_MYCTU
AccessioniPrimary (citable) accession number: O53459
Secondary accession number(s): F2GGG1, I6Y9N5, Q7D8U4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: August 1, 1998
Last modified: September 27, 2017
This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported