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Protein

Ribosome-binding ATPase YchF

Gene

ychF

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 176ATPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome-binding ATPase YchFUniRule annotation
Gene namesi
Name:ychFUniRule annotation
Ordered Locus Names:Rv1112Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1112.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: MTBBASE
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO53459.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1112.

Structurei

3D structure databases

ProteinModelPortaliO53459.
SMRiO53459. Positions 2-355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 250248OBG-type G (guanine nucleotide-binding)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3G. Bacteria.
COG0012. LUCA.
HOGENOMiHOG000087629.
KOiK06942.
OMAiCTIEPNI.
OrthoDBiEOG6NSGJC.
PhylomeDBiO53459.

Family and domain databases

Gene3Di1.10.150.300. 1 hit.
3.10.20.30. 1 hit.
3.40.50.300. 2 hits.
HAMAPiMF_00944. YchF_OLA1_ATPase.
InterProiIPR004396. ATPase_YchF/OLA1.
IPR012675. Beta-grasp_dom.
IPR013029. DUF933.
IPR031167. G_OBG.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR012676. TGS-like.
IPR023192. TGS-like_dom.
[Graphical view]
PfamiPF01926. MMR_HSR1. 1 hit.
PF06071. YchF-GTPase_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006641. CHP00092. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00092. TIGR00092. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O53459-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSLGIVGL PNVGKSTLFN ALTRNNVVAA NYPFATIEPN EGVVSLPDPR
60 70 80 90 100
LDKLAELFGS QRVVPAPVTF VDIAGLVKGA SEGAGLGNKF LAHIRECDAI
110 120 130 140 150
CQVVRVFVDD DVTHVTGRVD PQSDIEVVET ELILADLQTL ERATGRLEKE
160 170 180 190 200
ARTNKARKPV YDAALRAQQV LDAGKTLFAA GVDAAALREL NLLTTKPFLY
210 220 230 240 250
VFNADEAVLT DPARVGELRA LVAPADAVFL DAAIESELTE LDDESAAELL
260 270 280 290 300
ESIGQSERGL DALARAGFHT LKLQTFLTAG PKEARAWTIH QGDTAPKAAG
310 320 330 340 350
VIHSDFEKGF IKAEIVSYDD LVAAGSMAAA KAAGKVRIEG KDYVMADGDV

VEFRFNV
Length:357
Mass (Da):38,097
Last modified:August 1, 1998 - v2
Checksum:iC70A5951D18114D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43865.1.
RefSeqiNP_215628.1. NC_000962.3.
WP_003898732.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiCCP43865; CCP43865; Rv1112.
GeneIDi887151.
KEGGimtu:Rv1112.
mtv:RVBD_1112.
PATRICi18124276. VBIMycTub22151_1258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43865.1.
RefSeqiNP_215628.1. NC_000962.3.
WP_003898732.1. NZ_KK339370.1.

3D structure databases

ProteinModelPortaliO53459.
SMRiO53459. Positions 2-355.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1112.

Proteomic databases

PaxDbiO53459.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCP43865; CCP43865; Rv1112.
GeneIDi887151.
KEGGimtu:Rv1112.
mtv:RVBD_1112.
PATRICi18124276. VBIMycTub22151_1258.

Organism-specific databases

TubercuListiRv1112.

Phylogenomic databases

eggNOGiENOG4105C3G. Bacteria.
COG0012. LUCA.
HOGENOMiHOG000087629.
KOiK06942.
OMAiCTIEPNI.
OrthoDBiEOG6NSGJC.
PhylomeDBiO53459.

Family and domain databases

Gene3Di1.10.150.300. 1 hit.
3.10.20.30. 1 hit.
3.40.50.300. 2 hits.
HAMAPiMF_00944. YchF_OLA1_ATPase.
InterProiIPR004396. ATPase_YchF/OLA1.
IPR012675. Beta-grasp_dom.
IPR013029. DUF933.
IPR031167. G_OBG.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
IPR012676. TGS-like.
IPR023192. TGS-like_dom.
[Graphical view]
PfamiPF01926. MMR_HSR1. 1 hit.
PF06071. YchF-GTPase_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006641. CHP00092. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF81271. SSF81271. 1 hit.
TIGRFAMsiTIGR00092. TIGR00092. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiO53459_MYCTU
AccessioniPrimary (citable) accession number: O53459
Secondary accession number(s): F2GGG1, I6Y9N5, Q7D8U4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.