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Protein
Submitted name:

Probable short-chain dehydrogenase/reductase

Gene

Rv3174

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Probable short-chain dehydrogenase/reductaseImported
Submitted name:
Short-chain dehydrogenaseImported
Gene namesi
Ordered Locus Names:Rv3174Imported
ORF Names:LH57_17320Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv3174.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv3174.

Structurei

3D structure databases

SMRiO53324. Positions 3-205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZVM. Bacteria.
ENOG4111JN1. LUCA.
OMAiWVNGGEL.
OrthoDBiEOG6N3CR8.
PhylomeDBiO53324.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 1 hit.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

O53324-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSLAERTVL VTGANRGMGR EYVAQLLGRK VAKVYAATRN PLAIDVSDPR
60 70 80 90 100
VIPLQLDVTD AVSVAEAADL ATDVGILINN AGISRASSVL DKDTSALRGE
110 120 130 140 150
LETNLFGPLA LASAFADRIA ERSGAIVNVS SVLAWLPLGM SYGVSKAAMW
160 170 180 190 200
SATESMRIEL APRGVQVVGV YVGLVDTDMG RFADAPKSDP ADVVRQVLDG
210 220 230
IEAGKEDVLA DEMSRQVRAS LNVPARERIA RLMGN
Length:235
Mass (Da):24,849
Last modified:June 1, 1998 - v1
Checksum:i905543D65C52CB74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15958.1.
AL123456 Genomic DNA. Translation: CCP45985.1.
RefSeqiNP_217690.1. NC_000962.3.
WP_003900652.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR15958; AIR15958; LH57_17320.
CCP45985; CCP45985; Rv3174.
GeneIDi887989.
KEGGimtu:Rv3174.
mtv:RVBD_3174.
PATRICi18128934. VBIMycTub22151_3564.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15958.1.
AL123456 Genomic DNA. Translation: CCP45985.1.
RefSeqiNP_217690.1. NC_000962.3.
WP_003900652.1. NZ_KK339370.1.

3D structure databases

SMRiO53324. Positions 3-205.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv3174.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR15958; AIR15958; LH57_17320.
CCP45985; CCP45985; Rv3174.
GeneIDi887989.
KEGGimtu:Rv3174.
mtv:RVBD_3174.
PATRICi18128934. VBIMycTub22151_3564.

Organism-specific databases

TubercuListiRv3174.

Phylogenomic databases

eggNOGiENOG4108ZVM. Bacteria.
ENOG4111JN1. LUCA.
OMAiWVNGGEL.
OrthoDBiEOG6N3CR8.
PhylomeDBiO53324.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 1 hit.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiO53324_MYCTU
AccessioniPrimary (citable) accession number: O53324
Secondary accession number(s): I6X6K7, Q7D601
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: April 13, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.