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Protein
Submitted name:

Diguanylate cyclase

Gene

Rv3161c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • aromatic compound catabolic process Source: InterPro
  • response to organic substance Source: MTBBASE
Complete GO annotation...

Keywords - Molecular functioni

DioxygenaseImported, Oxidoreductase

Keywords - Ligandi

2Fe-2SUniRule annotation, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-7426-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Diguanylate cyclaseImported
Submitted name:
Possible dioxygenaseImported
Gene namesi
Ordered Locus Names:Rv3161cImported
ORF Names:LH57_17255Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv3161c.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: MTBBASE
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiO53311.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv3161c.

Structurei

3D structure databases

ProteinModelPortaliO53311.
SMRiO53311.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 161RieskeInterPro annotationAdd BLAST109

Sequence similaritiesi

Contains 1 Rieske domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108KK7. Bacteria.
COG4638. LUCA.
HOGENOMiHOG000220611.
OMAiVINGEDQ.
PhylomeDBiO53311.

Family and domain databases

Gene3Di2.102.10.10. 1 hit.
3.90.380.10. 1 hit.
InterProiIPR017941. Rieske_2Fe-2S.
IPR015879. Ring_hydroxy_dOase_asu_C_dom.
IPR001663. Rng_hydr_dOase-A.
[Graphical view]
PfamiPF00355. Rieske. 1 hit.
PF00848. Ring_hydroxyl_A. 1 hit.
[Graphical view]
PRINTSiPR00090. RNGDIOXGNASE.
SUPFAMiSSF50022. SSF50022. 1 hit.
PROSITEiPS51296. RIESKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O53311-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSTDNRAEL GDILTDIGDY LDDNPPALSL PPAAYTSSEL WQLERERIFN
60 70 80 90 100
RSWMLVAHVD QVAKTGDYVT VSVAGEPVMV VRDVDGQLHA LSPICRHRLM
110 120 130 140 150
LMVEPGAGRI DTLTCQYHLW RYGLDGRLRG APHMAANLDF NRRECRLPQF
160 170 180 190 200
AVATWNGLVW INLDADAEPI AAHLDLTDDE FAGYRLGEMV QVESWSHEWR
210 220 230 240 250
ANWKVAAENG HENYHVLGLH RQTLEPFVPG GGDLDVRQYS RWALRLRVPF
260 270 280 290 300
TVPVEAKSLQ LNEVQKSNLV VLWTFPNSAL AIAGERVVWF GFIPQSIDRV
310 320 330 340 350
QVLGGVLTTP ELAADAAATA QTSQFVMAMI NDEDRLGLEA VQVGAGSRFA
360 370 380
ERGHLSSKEW PGMLAFYRNL AMALVGDHPG AS
Length:382
Mass (Da):42,504
Last modified:June 1, 1998 - v1
Checksum:i56A1052E02E7BB81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15945.1.
AL123456 Genomic DNA. Translation: CCP45972.1.
RefSeqiNP_217677.1. NC_000962.3.
WP_003900647.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR15945; AIR15945; LH57_17255.
CCP45972; CCP45972; Rv3161c.
GeneIDi888800.
KEGGimtu:Rv3161c.
mtv:RVBD_3161c.
PATRICi18128908. VBIMycTub22151_3551.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15945.1.
AL123456 Genomic DNA. Translation: CCP45972.1.
RefSeqiNP_217677.1. NC_000962.3.
WP_003900647.1. NZ_KK339370.1.

3D structure databases

ProteinModelPortaliO53311.
SMRiO53311.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv3161c.

Proteomic databases

PRIDEiO53311.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR15945; AIR15945; LH57_17255.
CCP45972; CCP45972; Rv3161c.
GeneIDi888800.
KEGGimtu:Rv3161c.
mtv:RVBD_3161c.
PATRICi18128908. VBIMycTub22151_3551.

Organism-specific databases

TubercuListiRv3161c.

Phylogenomic databases

eggNOGiENOG4108KK7. Bacteria.
COG4638. LUCA.
HOGENOMiHOG000220611.
OMAiVINGEDQ.
PhylomeDBiO53311.

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-7426-MONOMER.

Family and domain databases

Gene3Di2.102.10.10. 1 hit.
3.90.380.10. 1 hit.
InterProiIPR017941. Rieske_2Fe-2S.
IPR015879. Ring_hydroxy_dOase_asu_C_dom.
IPR001663. Rng_hydr_dOase-A.
[Graphical view]
PfamiPF00355. Rieske. 1 hit.
PF00848. Ring_hydroxyl_A. 1 hit.
[Graphical view]
PRINTSiPR00090. RNGDIOXGNASE.
SUPFAMiSSF50022. SSF50022. 1 hit.
PROSITEiPS51296. RIESKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO53311_MYCTU
AccessioniPrimary (citable) accession number: O53311
Secondary accession number(s): F2GJL9, I6Y2T3, Q7D613
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: November 2, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.