O53232 (O53232_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Enoyl-CoA hydratase/isomerase family protein EMBL AAK47068.1

Submitted name:
Probable enoyl-CoA hydratase EchA15 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase) EMBL CCP45477.1

Gene names

Name:	echA15 EMBL CCP45477.1
Ordered Locus Names:	MT2753, Rv2679 EMBL CCP45477.1

Organism

Mycobacterium tuberculosis [Reference proteome] [HAMAP]

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the enoyl-CoA hydratase/isomerase family. RuleBase RU003707

Ontologies

Keywords
Molecular function	Isomerase EMBL AAK47068.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O53232 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 0E6C04B1DFC4A34C	FASTA	276	29,635
	10 20 30 40 50 60 MPVTYDDFPS LRCEIHDQPG HEGVLELVLD SPGLNSVGPH MHRDLADIWP VIDRDPAVRV 70 80 90 100 110 120 VLVRGEGKAF SSGGSFDLIA ETIGDYQGRL RIMREARDLV LNLVNFDKPV VSAIRGPAVG 130 140 150 160 170 180 AGLVVALLAD ISVAGRAAKI IDGHTKLGVA AGDHAAICWP LLVGMAKAKY YLLTCEPLSG 190 200 210 220 230 240 EEAERIGLVS ICVDDDDVLP TATRLAERLA AGAQNAIRWT KRSLNHWYRM FGPAFETSLG 250 260 270 LEFIGFGGPD VREGLAAHRE KRPARFGADP DPGAGS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv and H37Rv EMBL CCP45477.1.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
[3]	"Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv." Camus J.C., Pryor M.J., Medigue C., Cole S.T. Microbiology 148:2967-2973(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: H37Rv EMBL CCP45477.1.
[4]	"TubercuList--10 years after." Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. Tuberculosis 91:1-7(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: H37Rv EMBL CCP45477.1.
[5]	Lew J.M. Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: H37Rv EMBL CCP45477.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000516 Genomic DNA. Translation: AAK47068.1. AL123456 Genomic DNA. Translation: CCP45477.1.
PIR	H70869.
RefSeq	NP_217195.1. NC_000962.3. NP_337254.1. NC_002755.2. YP_006516123.1. NC_018143.1.
3D structure databases
SMR	O53232. Positions 4-266.
ModBase	Search...
Protein-protein interaction databases
STRING	83332.Rv2679.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK47068; AAK47068; MT2753.
GeneID	13319406. 887693. 925542.
KEGG	mtc:MT2753. mtu:Rv2679. mtv:RVBD_2679.
PATRIC	18127792. VBIMycTub22151_2995.
Organism-specific databases
TubercuList	Rv2679.
Phylogenomic databases
HOGENOM	HOG000027949.
KO	K01692.
OMA	TRVWHEA.
ProtClustDB	PRK07327.
Family and domain databases
InterPro	IPR001753. Crotonase_core_superfam. IPR018376. Enoyl-CoA_hyd/isom_CS. [Graphical view]
Pfam	PF00378. ECH. 1 hit. [Graphical view]
PROSITE	PS00166. ENOYL_COA_HYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O53232_MYCTU

Accession

Primary (citable) accession number: O53232
Secondary accession number(s): F2GLH7, Q7D6S5

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 1998
Last sequence update:	June 1, 1998
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)